A5028364292- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Photoacoustic and Ultrasonic Imaging
- Nanoparticle-Based Drug Delivery
- Extracellular vesicles in disease
- Luminescence Properties of Advanced Materials
- Luminescence and Fluorescent Materials
- MXene and MAX Phase Materials
- Graphene and Nanomaterials Applications
- Advanced biosensing and bioanalysis techniques
- Advanced Photocatalysis Techniques
- Photodynamic Therapy Research Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Quantum Dots Synthesis And Properties
- Hydrogen's biological and therapeutic effects
- 2D Materials and Applications
- Nanocluster Synthesis and Applications
- Carbon and Quantum Dots Applications
- 3D Printing in Biomedical Research
- Immune cells in cancer
- RNA Interference and Gene Delivery
- Electrocatalysts for Energy Conversion
- Dendrimers and Hyperbranched Polymers
Soochow University
2016-2025
Macau University of Science and Technology
2023-2025
Jilin University
2022-2025
Guangdong University of Petrochemical Technology
2025
State Key Laboratory on Integrated Optoelectronics
2025
Macao Polytechnic University
2024-2025
Institute of Molecular Functional Materials
2016-2025
East China University of Science and Technology
2024
Dana-Farber Cancer Institute
2024
Sun Yat-sen Memorial Hospital
2022-2024
MoS2 nanosheets functionalized with polyethylene glycol are for the first time used as a multifunctional drug delivery system high loading capacities. Using doxorubicin model and taking advantages of strong near-infrared absorbance MoS2, combined photothermal chemotherapy cancer is realized in animal experiments, achieving excellent synergistic anti-tumor effect upon systemic administration. As service to our authors readers, this journal provides supporting information supplied by authors....
A new generation of photothermal theranostic agents is developed based on PEGylated WS2 nanosheets. Bimodal in vivo CT/photoacoustic imaging reveals strong tumor contrast after either intratumoral or intravenous injection WS2-PEG. In treatment then conducted a mouse model, achieving excellent therapeutic efficacy with complete ablation tumors. This work promises further exploration transition-metal dichalcogenides for biomedical applications, such as cancer and therapy. As service to our...
In this work, a nanoscale reduced graphene oxide–iron oxide nanoparticle (RGO–IONP) complex is noncovalently functionalized with polyethylene glycol (PEG), obtaining RGO–IONP–PEG nanocomposite excellent physiological stability, strong NIR optical absorbance, and superparamagnetic properties. Using theranostic nanoprobe, in-vivo triple modal fluorescence, photoacoustic, magnetic resonance imaging are carried out, uncovering high passive tumor targeting, which further used for effective...
Poly(vinyl alcohol)-coated polypyrole, a conductive polymer that forms nanoparticles in the aqueous phase, is used as near-infrared light-absorbing agent for photothermal therapy of cancer, obtaining excellent cancer ablation therapeutic effects both cellular and animal experiments. Detailed facts importance to specialist readers are published "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by authors. Please note: The...
Much has been done to search for highly efficient and inexpensive electrocatalysts the hydrogen evolution reaction (HER), which is critical a range of electrochemical photoelectrochemical processes. A new, high-temperature solution-phase method synthesis ultrathin WS2 nanoflakes now reported. The resulting product possesses monolayer thickness with dimensions in nanometer abundant edges. These favorable structural features render active durable catalysts HER acids. catalyst exhibits small...
Jack of all trades: A multifunctional nanoparticle (MFNP) integrates an upconversion (see picture, green), a layer iron oxide nanoparticles (black), and gold shell (red). The system can be used for in vitro targeted luminescence, magnetic resonance, light scattering multimodal imaging cells. near-infrared optical absorption MFNPs also enables photothermal destruction cancer
Hollow Bi2 Se3 nanoparticles prepared by a cation exchange method are loaded with perfluorocarbon as an oxygen carrier. With these nanoparticles, promising concept is demonstrated to enhance radiotherapy not only using their X-ray-absorbing ability locally concentrate radiation energy in the tumor, but also employing near-infrared light trigger burst release of from overcome hypoxia-associated radio-resistance.
Abstract The delamination of titanium carbide sheets, an intriguing class two‐dimensional materials, has been critically dependent on the extraction interlayer Al in acidic media, such as concentrated hydrofluoric acid (HF) or a mixture hydrochloric (HCl) and fluoride salt. Herein, we report organic‐base‐driven intercalation that takes advantage amphoteric nature Al. resulting aluminum‐oxoanion‐functionalized sheets manifested unusually strong optical absorption near‐infrared (NIR) region...
The development of non precious metal based electrocatalysts for the hydrogen evolution reaction (HER) holds a decisive key to spectrum energy conversion technologies. Previous studies have established layered molybdenum chalcogenides as promising candidates. In this work, we prepared ultrathin MoS2(1–x)Se2x alloy nanoflakes with monolayer or few-layer thickness and fully tunable chemical composition maximum HER activity. Spectroscopic characterizations corroborate progressive their...
Theranostics for in vivo cancer diagnosis and treatment generally requires well-designed nanoscale platforms with multiple integrated functionalities. In this study, we uncover that functionalized iron oxide nanoparticles (IONPs) could be self-assembled on the surface of two-dimensional MoS2 nanosheets via sulfur chemistry, forming MoS2-IO nanocomposites, which are then modified two types polyethylene glycol (PEG) to acquire enhanced stability physiological environments. Interestingly, 64Cu,...
Multifunctional nanoplatforms that are safe and have multiple therapeutic functions together with imaging capabilities highly demanded in the development of new cancer theranostic approaches. A number near-infrared (NIR)-absorbing inorganic nanomaterials, although having shown great promise not only to photothermally ablate tumors but also enhance efficacy other types therapies, biodegradable would be retained body for a long time. Herein, we develop multifunctional nanocomposite by coating...
Recently, graphene oxide (GO) based nanocomposites have raised significant interests in many different areas, one of which being antibacterial agents where sliver nanoparticle (AgNPs) anchored GO (GO-Ag) has shown promising potential. However, to our best knowledge, factors affecting its activity as well the underlying mechanism remain unclear. In this study, we fabricate GO-Ag with AgNPs ratios and carefully investigate their activities against both Gram-negative (G-) bacteria Escherichia...
Abstract Sonodynamic therapy (SDT) triggered by ultrasound (US) has attracted increasing attention owing to its abilities overcome critical limitations including low tissue‐penetration depth and phototoxicity in photodynamic therapy. Herein, the design of a new type sonosensitizer is revealed, namely, ultrasmall oxygen‐deficient bimetallic oxide MnWO X nanoparticles, for multimodal imaging‐guided enhanced SDT against cancer. As‐made nanoparticles with poly(ethylene glycol) (PEG) modification...
Single-walled carbon nanotubes (SWNTs) with various unique optical properties are interesting nanoprobes widely explored in biomedical imaging and phototherapies. Herein, DNA-functionalized SWNTs modified noble metal (Ag or Au) nanoparticles via an situ solution phase synthesis method comprised of seed attachment, seeded growth, surface modification polyethylene glycol (PEG), yielding SWNT-Ag-PEG SWNT-Au-PEG nanocomposites stable physiological environments. With gold silver decorated on the...
Abstract The ultrahigh concentration of glutathione (GSH) inside tumors destroys reactive oxygen species (ROS)‐based therapy, improving the outcome chemodynamic therapy (CDT)‐enhanced sonodynamic (SDT) by depleting GSH is full great challenge. Herein, PtCu 3 nanocages are first reported as acting a sonosensitizer with highly efficient ROS generation under ultrasound irradiation. In addition, can act horseradish peroxidase‐like nanozymes, catalyzing decomposition H 2 O into • OH acidic...
Ultrasound (US)-triggered sonodynamic therapy (SDT) that enables noninvasive treatment of large internal tumors has attracted widespread interest. For improvement in the therapeutic responses to SDT, more effective and stable sonosensitizers are still required. Herein, ultrafine titanium monoxide nanorods (TiO1+x NRs) with greatly improved sono-sensitization Fenton-like catalytic activity were fabricated used for enhanced SDT. TiO1+x NRs an rodlike structure successfully prepared then...
In recent years, a wide range of near-infrared (NIR) light absorbing nanomaterials, mostly inorganic ones, have been developed for photothermal therapy (PTT) cancer. this work, we develop novel organic PTT agent based on poly-(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS), conductive polymer mixture with strong NIR absorbance, in vivo treatment After being layer-by-layer coated charged polymers and then conjugated branched polyethylene glycol (PEG), the obtained...