A5100708389- RNA modifications and cancer
- Molecular Sensors and Ion Detection
- Cancer-related molecular mechanisms research
- Electrocatalysts for Energy Conversion
- Fuel Cells and Related Materials
- Nanoplatforms for cancer theranostics
- Lung Cancer Diagnosis and Treatment
- Epigenetics and DNA Methylation
- RNA Research and Splicing
- Analytical Chemistry and Sensors
- Machine Learning in Materials Science
- Porphyrin and Phthalocyanine Chemistry
- Covalent Organic Framework Applications
- Autophagy in Disease and Therapy
- Sulfur Compounds in Biology
- Luminescence and Fluorescent Materials
- Lymphatic System and Diseases
- Cancer, Hypoxia, and Metabolism
- Circadian rhythm and melatonin
- Retinoids in leukemia and cellular processes
- Catalytic Processes in Materials Science
- Lung Cancer Treatments and Mutations
- Nitric Oxide and Endothelin Effects
- Cancer Genomics and Diagnostics
- Ferroptosis and cancer prognosis
Chizhou University
2016-2025
Advanced Energy Materials (United States)
2025
Peking Union Medical College Hospital
2016-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2024
An excellent electrocatalyst for producing H<sub>2</sub>O<sub>2</sub>was prepared from pristine CMK3 by microwave and subsequent liquid nitrogen treatments in 1 minute.
This study examined the effects of RNAi-mediated TUSC3 silencing on radiation-induced autophagy and radiation sensitivity human lung adenocarcinoma cell line A549 under hypoxic condition. Different CoCl2 concentrations were used to treat cells establish a CoCl2-induced model cells. MTT clone formation assays determine different growth proliferation treated by doses X-ray irradiation. The siRNA-expressing vector was transfected liposomes for TUSC3. Flow cytometry measure cycle changes...
Abstract Objectives Non–small‐cell lung cancer ( NSCLC ) is one of the leading causes deaths worldwide. Increasing levels visfatin are correlated with worse clinical prognosis . However, effects on drug resistant still not well illustrated. Materials and methods Effects cells were checked by CCK ‐8 kit. Gene protein variations measured real‐time PCR western blot analysis, respectively. Results Our present data confirmed that expression was significantly increased in tissues. In addition,...
Tumor-associated macrophages (TAMs), present within the tumor microenvironment (TME), strictly modulate angiogenesis and lymphangiogenesis. Nevertheless, associated signaling networks candidate drug targets for these events remains to be elucidated. Given its antioxidative activities, we speculated that melatonin may reduce pyroptosis, thereby both We revealed a co-culture of A549 cells THP-1 strongly enhanced expressions NLRP3 inflammasome axis members, augmented Next, overexpressed in...
The incidence of multiple primary lung cancer (MPLC) is increasing, with some our surgical patients exhibiting numerous lesions. We defined five or more lesions as super MPLCs. Elucidating the genomic characteristics this special MPLC subtype can help reduce disease burden and understand tumor evolution. In cohort synchronous early-stage MPLCs (PUMCH-ssesMPLC), whole-exome sequencing on 130 resected malignant specimens from 18 provided comprehensive super-MPLC landscapes. Mutations are...
Microbes play a significant role in human tumor development and profoundly impact treatment efficacy, particularly immunotherapy. The respiratory tract extensively interacts with the external environment possesses mucosal immune system. This prompts consideration of relationship between microbiota lung cancer. Advancements culture-independent techniques have revealed unique communities within lower tract. Here, we provide an overview composition, dysbiosis characteristics cancer patients,...
Abstract Introduction: Lung cancer found at an early stage carries much-improved prognosis. Unfortunately, there has been little success in developing blood-based diagnostic method. Profiling somatic mutations from ctDNA shown great promise for diagnosis, prognosis, and surveillance. Despite the substantial advances made detection techniques, rate remains low disease. The role of aberrant DNA methylation process tumorigenesis both individual genes a genome-wide scale well elucidated. It...
Abstract Although mortality rate has been greatly reduced by low-dose computed tomography (LDCT) screening of high-risk patients, the benefit is compromised high false-positive rate, thus necessitating development biomarkers differentiating benign and malignant nodules. The role aberrant DNA methylation in process tumorigenesis both at individual genes a genome-wide scale well elucidated. It occurs very early cancer development, capable serving as diagnostic biomarker. In this prospective...
Abstract Background: Lung adenocarcinoma (LUAD) is the most heterogeneous and aggressive among all NSCLC subtypes. This work aimed to determine predictive ability of DYNLL1 RAN in LUAD, as well explore role possible Ran molecular mechanisms on LUAD malignant behavior. Methods: Using data from Cancer Genome Atlas Genotype-Tissue Expression, we compared expression its related gene normal lung tissues. We also studied prognostic value terms overall survival (OS) liver cancer renal patients....