The promotion of osteoblast attachment and differentiation has been evaluated on various implant surfaces. However, the effects different surface properties gene expression key osteogenic factors are not fully understood.The objectives this study were to evaluate how topographical titanium alter bone-related genes transcription factors.Osteoblasts cultured disks prepared with a dioxide grit blasting (TiOBlast) or blasted etched hydrofluoric acid (Osseospeed), (SLA-1), blasted, rinsed N2...

Poly(methyl methacrylate) (PMMA) is widely used in dental applications. However, PMMA specialized for stereolithography (SLA) additive manufacturing (3D-printing) has not been developed yet. This study aims to develop a novel PMMA-based resin SLA 3D-printing by mixing methyl methacrylate (MMA), ethylene glycol dimethacrylate (EGDMA), and powder various ratios. The printability the viscosity of resins were examined determine their suitability 3D-printing. mechanical properties (flexural...

ABSTRACT Objectives The necessity of a second molar region implant for Kennedy Class II classification unilateral partially edentulous arches remains controversial. This study aims to compare the effects treatment in first and regions, providing basis planning treatments dentition. Methods prospective cohort included 16 patients with therapy up treated molar. Bite force, masticatory function, oral health‐related quality life (OHRQoL), food nutrient intakes were evaluated as outcomes. Results...

The relationship between sarcopenic obesity and masticatory function is poorly understood. This study aims to explore this association in community-dwelling individuals aged 75 years or older. analyzed data from 236 adults Masticatory was assessed using spectrophotometric measurement of gum color differences before after chewing color-changeable (ΔE*ab). Participants were categorized into tertiles based on their ΔE*ab values. defined as low, intermediate, high. Sarcopenic the Consensus...

Low-intensity pulsed ultrasound (LIPUS) has been used in fracture treatment to shorten the time needed for biologic wound healing. Clinical trials applying LIPUS implant dentistry have reported accelerated soft-tissue healing and osseointegration. However, details of clinical effects not well characterized. Connective tissue growth factor (CCN2/CTGF) plays an important role angiogenesis periodontal tissue. In this study, we focus on effect gingival epithelial cells CCN2/CTGF therein.Gingival...

Poly(methyl methacrylate) (PMMA)-based resins have been conventionally used in dental prostheses owing to their good biocompatibility. However, PMMA-based relatively poor mechanical properties. In the present study, a novel nanoporous silica filler was developed and introduced into improve The prepared by sintering green body composed of an organic binder, followed grinding fine powder subsequent silanization. added photocurable resin, which from MMA, PMMA, ethylene glycol dimethacrylate,...

Summary To treat sleep bruxism ( SB ), symptomatic therapy using stabilisation splints SS ) is frequently used. However, their effects on psychological stress and quality have not yet been examined fully. The objective of this study was to clarify the use quality. subjects (11 men, 12 women) were healthy volunteers. A crossover design Sleep measurements performed for three consecutive days or longer without (baseline) with an palatal splint PS data final day evaluated. We measured masseter...

Polymer infiltrated ceramic network (PICN) composites are an increasingly popular dental restorative material that offer mechanical biocompatibility with human enamel. This study aimed to develop a novel PICN composite as computer-aided design and manufacturing (CAD/CAM) block for applications. Several were prepared under varying conditions via the sintering of green body from silica-containing precursor solution, followed by resin infiltration. The flexural strength (107.8–153.7 MPa) was...

Poly-ether-ether-ketone (PEEK) is commonly employed in dental prostheses owing to its excellent mechanical properties; however, it limited by low bond strength with resin cement. This study aimed clarify the type of cement most suitable for bonding PEEK: methyl methacrylate (MMA)-based or composite-based For this purpose, two MMA-based cements (Super-Bond EX and MULTIBOND II) five (Block HC Cem, RelyX Universal Resin Cement, G-CEM LinkForce, Panavia V5, Multilink Automix) were used...

Zirconia is often used for implant abutments esthetics. The aim of this clinical study was to compare the effects zirconia and metal on periimplant soft tissue.Ten maxillary anterior patients, 5 with abutments, were enrolled in trial. tissue around evaluated by 2-dimensional laser speckle imaging thermography. blood flow natural teeth also measured correct differences among subjects.Significantly greater detected abutment group (95.64 ± 5.17%) relative (82.25 8.92%) free gingiva (P =...

Oral ulcer is the most common oral disease and leads to pain during meals speaking, reducing quality of life patients. Recent evidence using animal models suggests that ulcers induce cyclooxygenase-dependent spontaneous cyclooxygenase-independent mechanical allodynia. Endothelin-1 upregulated in mucosal inflammation, although it has not been shown ulcers. In present study, we investigated involvement endothelin-1 signaling with ulcer–induced our proprietary assay system conscious rats. was...

Corticosteroids are used in the treatment of many diseases; however, they also induce various side effects. Dexamethasone is one most potent corticosteroids, and it has been reported to effect impaired salivary gland function. This study aimed evaluate effects dexamethasone on mouse submandibular function gain insight into mechanism dexamethasone-induced hypofunction. The muscarinic agonist carbachol (CCh) induced secretion was not affected by short-term but decreased following long-term...

Abstract Objective The aims of this clinical study were to determine differences in plaque accumulation and compare the effects reinforced composite resin titanium on peri‐implant soft‐tissue residual‐ridge inflammation. Material methods A total 19 subjects enrolled trial; 10 jaws had implant‐supported fixed prostheses with mucosal surfaces, 11 fabricated by computer‐aided design/computer‐aided manufacture ( CAD / CAM ), 6 acrylic prostheses. Plaque area indexes PAIs ) calculated surfaces...

The objective of this study is to evaluate the impact thickness and translucency various computer-aided design/computer-aided manufacturing (CAD/CAM) materials on polymerization dual-cure resin cement in endocrown restorations. Three commercially available CAD/CAM materials—lithium disilicate glass (e.max CAD), composite (CERASMART), a polymer-infiltrated ceramic network (ENAMIC)—were cut into plates with five different thicknesses (1.5, 3.5, 5.5, 7.5, 9.5 mm) both high-translucency (HT)...

Glucagon-like peptide 1 (GLP-1) is secreted from the small intestine to blood in response glucose intake during a meal; however, it not known whether mastication affects GLP-1 secretion. Here, we examined relationship between and secretion, along with postprandial insulin concentrations. We compared levels of glucose, serum insulin, plasma active concentrations after young healthy volunteers ate test meal either by usual eating (control) or one three specified ways: 1. unilateral chewing, 2....

The quality and quantity of mandibular bone are essential prerequisites for osseointegrated implants. Only the Hounsfield unit on preoperative computed tomography is currently used as a clinical index. Nevertheless, considerable mismatch occurs between unit. Loss toughness during aging has been accepted based empirical evidence, but this concept unlikely evidence at level mechanical properties. Nonenzymatic matrix cross-links associated with advanced glycation end products predominate...

The solute carrier family 26 (SLC26) gene encodes at least 10 different anion exchangers. SLC26 member 6 (SLC26A6 or CFEX/PAT-1) and the cystic fibrosis transmembrane conductance regulator (CFTR) co-localize to apical membrane of pancreatic duct cells, where they act in concert drive HCO3- fluid secretion. In contrast, small intestine, SLC26A6 serves as major pathway for oxalate However, little is known about function Slc26a6 murine salivary glands. Here, RNA sequencing-based transcriptional...