A5023892667- Exercise and Physiological Responses
- Sports Performance and Training
- Cardiovascular and exercise physiology
- Muscle metabolism and nutrition
- Muscle activation and electromyography studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Thermoregulation and physiological responses
- Chemotherapy-induced cardiotoxicity and mitigation
- Heart Rate Variability and Autonomic Control
- Immune Cell Function and Interaction
- Cerebral Palsy and Movement Disorders
- Sports injuries and prevention
- Cardiovascular Effects of Exercise
- Balance, Gait, and Falls Prevention
- COVID-19 Clinical Research Studies
- School Health and Nursing Education
- Healthcare cost, quality, practices
- Mindfulness and Compassion Interventions
- Genetics and Physical Performance
- Bone Tumor Diagnosis and Treatments
- Neonatal and fetal brain pathology
- Dermatological and Skeletal Disorders
- HIV-related health complications and treatments
- Stress Responses and Cortisol
- Doping in Sports
Florida Institute for Human and Machine Cognition
2024-2025
University of West Florida
2024-2025
Creighton University
2016-2024
American College of Surgeons
2015-2018
University of Kansas
2014-2016
University of Wisconsin–Madison
2016
ABSTRACT Assessment of heart rate variability (HRV) is a common approach to examine cardiac autonomic nervous system modulation that has been employed in variety settings. Frequently, both the root mean square successive differences (RMSSD) and SD1, which Poincaré plot component, have used quantify short‐term variability. It not typically appreciated, however, RMSSD SD1 are identical metrics HRV. As reminder clinicians researchers who use study HRV, we show empirically mathematically...
Background Neutralizing-antibody (nAb) is the major focus of most ongoing COVID-19 vaccine trials. However, nAb response against SARS-CoV-2, when present, decays rapidly. Given myriad roles antibodies in immune responses, it possible that could also mediate protection SARS-CoV-2 via effector mechanisms such as antibody-dependent cellular cytotoxicity (ADCC), which we sought to explore here. Methods Plasma 3 uninfected controls and 20 subjects exposed to, or recovering from, infection were...
Conventional belief is that high-intensity (HI) exercise inhibits immune function; however, recent work challenges this position. The purpose of was to quantify changes in T cell proliferative capacity following either a HI or moderate-intensity (MI) exercise. Sixteen males were randomly selected MI group. Blood obtained baseline and immediately, 1-, 4-, 6-hours post-exercise for analyses CD3+ proliferation (co-stimulation via PHA CD3+CD28). response increased cells the group remained...
The effect of instrument-assisted soft tissue mobilization (ISTM) on passive properties and inflammation in human skeletal muscle has not been evaluated. Passive muscle, inflammatory myokines subjective reporting functional ability were used to identify the effects ISTM plantar flexors. 11 healthy men measured for musculotendinous stiffness (MTS), range motion (PROM), resistive torque (PASTQ) maximum voluntary contraction peak (MVCPT) flexor muscles lower leg. Interleukin-6 (IL-6) tumor...
We examined motor unit (MU) control properties of resistance-trained (RT) and endurance-trained (ET) individuals.Five RT (age 25 ± 4 years) 5 ET 19 1 subjects participated. Surface electromyography (EMG) data were recorded from the vastus lateralis during isometric trapezoid muscle actions at 40% 70% maximal voluntary contraction. Decomposition wavelet transform techniques applied to EMG signals extract firing events single MUs intensity across frequency spectrum.There significant...
Asthma is a common chronic childhood disease worldwide. Socioeconomic status, genetic predisposition and environmental factors contribute to its incidence severity. A disproportionate number of children with asthma are economically disadvantaged live in substandard housing potential indoor exposures such as cockroaches, dust mites, rodents molds. These may manifest through epigenetic mechanisms that can lead changes relevant gene expression. We examined the association global DNA methylation...
Context Various modalities have been used to pretreat skeletal muscle attenuate inflammation. Objective To determine the effects of short-wave diathermy (SWD) preheating treatment on inflammation and stress markers after eccentric exercise. Design Controlled laboratory study. Setting University setting. Patients or Other Participants Fifteen male (age = 22 ± 4.9 years, height 179.75 9.56 cm, mass 82.22 12.67 kg) college-aged students. Intervention(s) Seven participants were selected randomly...
Spinal cord injury (SCI) results in rapid muscle atrophy and an oxidative-to-glycolytic fiber-type shift. Those with chronic SCI are more at risk for developing insulin resistance reductions glucose clearance than able-bodied individuals, but how metabolism is affected after not well known. An untargeted metabolomics approach was utilized to investigate changes whole-muscle metabolites acute (7-day) subacute (28-day) time frame a complete T9 spinal transection 20-week-old female C57BL/6...
A momentous amount of health data has been and is being collected. Across all levels care, are driving decision-making impacting patient care. new field knowledge role for those in care emerging-the need a data-informed workforce. In this viewpoint, we describe the approaches needed to build workforce, critical skill ecosystem.
Traumatic spinal cord injury (SCI) results in wide-ranging cellular and systemic dysfunction the acute chronic time frames after injury. Chronic SCI has well-described secondary medical consequences while unique metabolic challenges as a result of physical trauma, in-patient recovery other post-operative outcomes. Here, we used high resolution mass spectrometry approaches to describe circulating lipidomic metabolomic signatures using blood serum from mice 7 d complete SCI. Additionally,...
Previous research has shown that resistance training (RT) before doxorubicin (DOX) treatment attenuates the decline in muscle dysfunction; however, effect of RT during DOX is less known.Investigate effects and a 4-wk course incremental on skeletal function.Male, Sprague-Dawley rats (N = 36) were randomly assigned to following groups: sedentary+saline (SED + SAL), sedentary+DOX DOX), SAL, or DOX. The protocol utilized raised cage model, which provided progressive hindlimb loading throughout...
Gastrointestinal (GI) disturbances are a prevalent cause of marathon related complaints, and in extreme cases can promote life-threatening conditions such as exertional heat stroke. Our aim was to study intestinal cell injury [via fatty acid binding protein (I-FABP)] perceived GI distress symptoms among runners. We also examined potential risk factors (e.g., inadequate sleep) that could exacerbate healthy, trained endurance This parallel mixed-methods design. 2019 Boston Marathon...
Early studies in exercise immunology suggested acute bouts of had an immunosuppressive effect human subjects. However, recent data, show combined aerobic and resistance training increase both lymphocyte activation proliferation. We quantified exercise-induced changes the state CD4+ T lymphocytes via surface protein expression using a medically relevant model infection (HIV-1). Using randomized cross-over design, 10 untrained subjects completed control session. The session consisted 30-min...
This investigation aimed to determine the effect of a multi-ingredient pre-workout supplement (MIPS) on heart rate (HR), perceived exertion (RPE), lactate concentration, and time fatigue (TTF) during running task volitional exhaustion. Eleven NCAA Division I cross-country runners (20 ± 2 year; height: 171 14 cm; weight: 63.5 9.1 kg) participated in this randomized, double-blind, placebo-controlled cross-over study. Bayesian statistical methods were utilized, parameter estimates interpreted...
Doxorubicin (DOX), a potent chemotherapy agent, useful in the treatment of solid tumors, lymphomas, and leukemias, is limited by its potentially lethal cardiotoxicity. However, exercise has been consistently shown to mitigate side effects DOX, including To date, most studies examining relationship between DOX-induced cardiotoxicity have focused on aerobic exercise, with very few role anerobic activity. Therefore, this investigation explored potential creatine (CR) resistance training (RT)...
The current study examined differences in heart rate variability (HRV) across student-athletes of different eligibility classifications and analyzed HRV when competing at home or away. Fourteen female collegiate volleyball players volunteered for the study. Data collection encompassed an entire season, with comparisons made between away games, as well pre-gameday, gameday, post-gameday recordings whole squad. Comparisons were also student-athlete classification, self-reported measures sleep...
This study investigated the effect of a commercially available ketone supplement on heart rate (HR), perceived exertion (RPE), blood lactate, glucose, and concentrations, along with time to fatigue (TTF) during running task voluntary fatigue. Twelve NCAA Division I cross-country athletes took part in this randomized, double-blind, placebo-controlled cross-over study. Bayesian methodologies were employed for all statistical analyses, point estimates determined be statistically significant if...
Resistance training at fast velocities is suggested to be more effective for improving muscular strength and movement speed compared slow, heavy training. This study aimed examine the effects of a fast-velocity (FVRT) slow-velocity (SVRT) resistance program on maximal strength, speed, load-velocity characteristics in older adults. Nineteen community-dwelling adults were randomly assigned either FVRT or SVRT group completed twice weekly, progressive protocol 8-weeks. Both groups instructed...
Abstract Traumatic spinal cord injury (SCI) results in wide-ranging cellular and systemic dysfunction the acute chronic time frames after injury. Chronic SCI has well-described secondary medical consequences while unique metabolic challenges as a result of physical trauma, in-patient recovery other post-operative outcomes. Here, we used high resolution mass spectrometry approaches to describe circulating lipidomic metabolomic signatures using blood serum from mice 7 d complete SCI....
The Marine Corps Martial Arts Program (MCMAP) was developed to prepare Marines for complex battlefield situations that include hand-to-hand combat and ethical decision making. objective of this study quantify changes in decision-making following MCMAP training. Fifty-five, active duty, newly enlisted U.S. (Males: n = 37; age 19 ± 1 years; height 176 7 cm; mass 74 kg; Females: 18; 20 2 164 6 61 kg) volunteered investigation were assessed three times over weeks, with 3 weeks between each...