- Heart Failure Treatment and Management
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Palliative Care and End-of-Life Issues
- Transplantation: Methods and Outcomes
- Childhood Cancer Survivors' Quality of Life
- Treatment of Major Depression
- Family and Patient Care in Intensive Care Units
- Geriatric Care and Nursing Homes
- Eosinophilic Disorders and Syndromes
- Cardiovascular Function and Risk Factors
- Mental Health Research Topics
- Healthcare Policy and Management
- Liver Disease Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cardiac Arrest and Resuscitation
- Lipoproteins and Cardiovascular Health
- Chronic Myeloid Leukemia Treatments
- Quality and Safety in Healthcare
- Cardiovascular Issues in Pregnancy
- Cardiac pacing and defibrillation studies
- Healthcare Technology and Patient Monitoring
- Liver Disease and Transplantation
- Cardiovascular Health and Risk Factors
Northwestern University
2017-2024
Northwestern Memorial Hospital
2024
The University of Texas Southwestern Medical Center
2024
Northwestern Medicine
2024
University of Pennsylvania
2024
Midwestern University
2023
Hospital of the University of Pennsylvania
2018
Massachusetts General Hospital
2009-2010
Harvard University Press
2010
Harvard University
2009-2010
The objective of this study was to assess the relationship between early changes in anxiety/somatization symptoms and treatment outcome among major depressive disorder patients during a 12-week trial fluoxetine. We also examined anxious depression response. Five hundred ten received 12 weeks fluoxetine with flexible dosing [target dosages: 10 mg/day (week 1), 20 (weeks 2-4), 40 4-8), 60 5-12)]. assessed 17-item Hamilton Rating Scale for Depression (HAMD-17)-anxiety/somatization factor items...
Background: The location of death is an important component end-of-life care. However, contemporary trends in the for cardiovascular deaths related to heart failure (CV-HF) and comparison cancer have not been fully examined. Methods: We analyzed data from Centers Disease Control Prevention’s Wide-Ranging Online Data Epidemiologic Research database between 2003 2017 identify CV-HF deaths. proportions that occurred a hospice facility, home, medical facility were tested using linear regression....
Elderly subjects have reduced mitochondrial function. However, it remains unclear whether the decline in function begins earlier life span.The objective of study was to determine skeletal muscle oxidative phosphorylation by (31)phosphorous-magnetic resonance spectroscopy (MRS) across a variety age groups.This cross-sectional 121 healthy normal-weight and overweight individuals from 8 55 yr.The conducted at single university medical center Boston, MA.Participants included 68 children 53...
Purpose of review Heart failure (HF) is characterized by significant symptoms, compromised quality life, frequent hospital admissions, and high mortality, therefore well suited to palliative care (PC) intervention. This elaborates the current PC needs patients with HF across spectrum disease, including who undergo advanced surgical therapies, reviews data future directions for integration in care. Recent findings Patients chronic HF, as those are being evaluated or have undergone therapies...
BACKGROUND: In October 2018, the US heart transplant (HT) allocation system was revised giving patients with left ventricular assist device (LVAD) intermediate priority status. Few studies have examined impact of this policy change on outcomes among LVAD. We sought to determine how impacted waitlist and posttransplant mortality in METHODS: retrospectively assessed United Network for Organ Sharing registry LVAD who were listed or underwent HT between 2016 2021. evaluated using competing risks...
Relapse of major depressive disorder (MDD) is a common clinical problem. This study was designed to determine whether residual sleep disturbance (insomnia and hypersomnia) predict risk relapse during the continuation maintenance treatment MDD.A total 570 patients with MDD were treated open-label, flexible dose fluoxetine (range 20 60 mg; mean = 45.8 mg/day; SD 15.1) for 12 weeks. Under double blind conditions, 262 who achieved response randomly assigned continue or switch placebo 52 weeks...
Background Patients with left ventricular assist devices (LVADs) implanted as destination therapy may receive suboptimal preparation for and care at the end of life, but there is limited understanding reasons these shortcomings. Exploring perceptions individuals (caregivers clinicians) who are closely involved in end-of-life experience patients LVADs can help identify key opportunities improving care. Methods Results We conducted semistructured qualitative interviews 7 bereaved caregivers 10...