A5053204813- EEG and Brain-Computer Interfaces
- Sleep and related disorders
- Sleep and Wakefulness Research
- Down syndrome and intellectual disability research
- Obstructive Sleep Apnea Research
- Blind Source Separation Techniques
- Neural dynamics and brain function
- Health and Lifestyle Studies
- Transcranial Magnetic Stimulation Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Sleep and Work-Related Fatigue
- ECG Monitoring and Analysis
- Ethics and bioethics in healthcare
- Neuroscience of respiration and sleep
- Aging, Health, and Disability
- Cardiovascular Syncope and Autonomic Disorders
- Neurotransmitter Receptor Influence on Behavior
- Heart Rate Variability and Autonomic Control
- Psychedelics and Drug Studies
- Hallucinations in medical conditions
- Analog and Mixed-Signal Circuit Design
- Developmental and Educational Neuropsychology
- Vestibular and auditory disorders
- Cerebral Venous Sinus Thrombosis
- Medical Malpractice and Liability Issues
Hospital de Sant Pau
2002-2023
Universitat Autònoma de Barcelona
2004-2022
Centro de Investigación Biomédica en Red de Salud Mental
2011-2018
Centro de Investigación Biomédica en Red
2018
Centre d’Investigació i Desenvolupament
2011
Vall d'Hebron Institut de Recerca
2005
Sleep problems are often undetected in adults with Down syndrome (DS). Our objective was to determine the prevalence of sleep disorders DS through self-reported and measures.We performed a community-based cross-sectional study 54 not referred for disorders. Two polysomnography (PSG) studies were performed. quality evaluated using Pittsburgh Quality Index (PSQI); daytime sleepiness Epworth Sleepiness Scale (ESS) risk apnea (OSA) identified Berlin Questionnaire (BQ). Participants' sleep/wake...
Contamination of sleep EEG signals by the eye, muscle and heart activity is a problem for interpretation analysis disorders influence drugs. The aim this paper to evaluate method artifact reduction applied in different stages: awakeness, stage 2, delta REM sleep. Artifacts, particularly certain types, may be more likely found particular settings stages To overcome limitation regression methods bidirectional contamination, based on Independent Component Analysis (ICA) using time structure...
<i>Aims:</i> To evaluate the potential interaction of 20 mg paroxetine and 1 alprazolam (early morning once-daily administration) on polysomnographic (PSG) sleep subjective awakening quality, both after a single intake reaching steady-state concentration. <i>Methods:</i> Twenty-two (11 for PSG) healthy young volunteers sexes with no history disturbances (Pittsburgh Sleep Quality Index <5) participated in double-blind, double-dummy, placebo-controlled,...
Objective Polysomnography abnormalities are frequent in schizophrenia and have been correlated with clinical variables. Because women present a general better outcome than men, we aimed to determine whether sex differences antipsychotic‐induced effects on sleep could contribute this difference. Methods Single oral morning doses of olanzapine (5 mg) were administered 10 men women. Sleep variables evaluated using traditional polysomnography Rechstschaffen Kales criteria all‐night...
Electroencephalographic artifacts associated with eye movements are a potential source of error in the EEG analysis when its interpretation is performed for evaluating influence drugs and diagnosis neurological disorders. In this study, new automatic method artifact filtering based on independent component (ICA) proposed. Automatic identification frequency domain scalp topography aspects components. A comparative study between ICA 'gold standard' linear regression performed. The latter does...
Down syndrome (DS) is a genetic form of Alzheimer's disease (AD) with high prevalence obstructive sleep apnea (OSA). These characteristics place the DS population as an optimal model to study relationship between and AD design clinical trials preventive therapies for AD. Regrettably, OSA treatment continuous positive airway pressure (CPAP) often neglected in adults DS. In both practice research trials, it usually presumed that these patients will not adapt or tolerate therapy.We aimed...
The time course of the pupillary light reflex (PLR) is determined by successive activation parasympathetic and sympathetic innervations iris, latency amplitude reflecting activity recovery showing mainly activity.To determine effects tobacco cigarette smoking on PLR in smokers after an abstinence period at least 12 h.Ten (mean 15.7 cigarettes/day) 10 non-smokers participated a randomised, non-intervention controlled, cross-over study that included parallel control group. Smokers underwent...
Abstract Background Down syndrome (DS) is a genetic form of Alzheimer’s disease (AD) with preclinical AD biomarker changes similar to euploid forms AD. In sporadic AD, sleep electroencephalogram (EEG) have been related cognitive decline and progression. However, whether DS follows pattern EEG has not investigated. Here, we aimed quantify in adults using spectral analysis entropy changes. Method Cross‐sectional study, 67 (41.1±11.4 yo) without signs decline, 24 (58.3±12.4 performed...
Abstract Background Sex differences in biological factors, such as sleep, might contribute to sex dementia risk. Down’s syndrome (DS) is a genetically determined form of Alzheimer’s disease (AD), with disrupted sleep and high prevalence obstructive apnea (OSA). However, nocturnal adults DS have not been yet investigated. Thus, we aimed evaluate the effect on polysomnographic measures DS. Method Cross‐sectional study 187 from Down‐Alzheimer Barcelona Neuroimaging Initiative (DABNI) that...