A5037896492- Cardiovascular Function and Risk Factors
- Diabetes Treatment and Management
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Hormonal Regulation and Hypertension
- Blood Pressure and Hypertension Studies
- Poisoning and overdose treatments
- Diet and metabolism studies
- Heart Failure Treatment and Management
- Parathyroid Disorders and Treatments
- Neurological and metabolic disorders
- Kidney Stones and Urolithiasis Treatments
- Forensic Toxicology and Drug Analysis
- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Magnesium in Health and Disease
- Hepatitis C virus research
- Potassium and Related Disorders
- Heavy Metal Exposure and Toxicity
- Immunodeficiency and Autoimmune Disorders
- Porphyrin Metabolism and Disorders
- Cytomegalovirus and herpesvirus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Healthcare Policy and Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
Kidney Associates
2021-2023
Autonomous University of Tlaxcala
2020
Texas Tech University
2006-2017
Texas Tech University Health Sciences Center
2006-2017
San Francisco General Hospital
2006
University of California, San Francisco
2006
Hospital Universitario Reina Sofía
2006
Stanford University
1995
Female, 66 FINAL DIAGNOSIS: Chorea • hyperglycemia Basal Ganglia Syndrome (C-H-BG) Symptoms: Hemibalism hemichorea- Clinical Procedure: - Specialty: Endocrinology and Metabolic.Challenging differential diagnosis.Hemichorea-hemiballism (HCHB) is a spectrum of involuntary, continuous non-patterned movement involving 1 side the body. Possible causes HCHB include hemorrhagic or ischemic stroke, neoplasm, systemic lupus erythematosus, HHNK, Wilson's disease, thyrotoxicosis. This case illustrates...
Implication for health policy/practice/research/medical education:The ability to identify diabetic patients at high risk progressive renal decline should be one of the priorities nephrology community.Early identification may lead improved clinical management, quality life, and a decrease in already burden morbidity.An ideal biomarker relatively inexpensive readily measured either serum or urine.
Finerenone, a selective nonsteroidal MRA, and SGLT2is both reduce CKD progression improve kidney/CV outcomes. The CONFIDENCE study (NCT05254002; EudraCT 2021-003037-11) hypothesis is that early combination of finerenone empagliflozin, SGLT2i, superior to either drug alone in reducing UACR over 6 months. an ongoing, fully enrolled, randomized, controlled, double-blind, multicentre phase 2 clinical trial adults (≥18 years age) with T2D, eGFR 30 90 ml/min/1.73 m2, ≥100 <5000 mg/g. Participants...
Herlitz junctional epidermolysis bullosa is an autosomal recessive disorder characterized by generalized blistering at the lamina lucida of cutaneous basement membrane. The monoclonal antibody GB3 has been used as a diagnostic probe because its lack reactivity in patient skin. antigen recognized identified laminin-5, glycoprotein consisting three subunits (alpha 3, beta 3 and gamma 2). To identify laminin-5 protein chain that contains epitope to determine if assembly required for...
Healthy People 2020 aim to reduce fatal atherosclerotic cardiovascular disease (ASCVD) by 20%, which translates into 310 000 fewer events annually assuming proportional reduction in and nonfatal ASCVD. We estimated preventable ASCVD implementing the American College of Cardiology/American Heart Association (ACC/AHA) 2013 Cholesterol Guideline all statin-eligible adults. Absolute risk (ARR) number needed-to-treat (NNT) were calculated.National Health Nutrition Examination Survey data for...
Implication for health policy/practice/research/medical educationIn 2014 World Kidney Day (WKD) will focus on chronic kidney disease and aging. The mission of WKD is to raise awareness so that everyone cares their kidneys and, if appropriate, check assess they are at risk disease. Prevention disease, early detection, subsequent protection critical aims WKD.
Hemodialysis patients are at increased risk of hepatitis B virus (HBV) infection and poorly responsive to HBV vaccines. Current vaccine recommendations for hemodialysis utilize more than twice the amount surface antigen (HBsAg) used healthy adults achieve lower immune responses.An open-label, single-arm, multicenter trial was conducted among 18 years age older who were initiating or undergoing had not previously received vaccine. Participants four doses HepB-CpG (HEPLISAV-B®) (20 mcg rHBsAg...
Background: Porphyria cutanea tarda (PCT) is the most common type of porphyria. It occurs due to deficiency enzyme uroporphyrinogen decarboxylase (UROD), which fifth in biosynthesis heme and catalyzes conversion coproporphyrinogen. The risk factors for PCT include hereditary hemochromatosis, hepatitis C infection, ethanol abuse, estrogen use, HIV, smoking, chlorinated polycyclic aromatic hydrocarbons, hemodialysis. Case Report: A 47-year-old Hispanic man presented with right thumb swelling,...
Ethylene glycol ingestion can lead to acute kidney injury from tubular deposition of oxalate crystals. The diagnosis ethylene intoxication is based on a history ingestion, clinical examination, high anion gap metabolic acidosis, osmolal gap, and measured serum level glycol. However, depending the delay in time arrival hospital, may become normal, thereby creating confusing clinic picture for treating clinician.A 71 year-old man with alcohol abuse had been unconscious an unknown period time....
A 2014 hypertension guideline raised goal systolic blood pressure (SBP) from <140 mm Hg to <150 for adults 60 years and older without diabetes mellitus (DM) or chronic kidney disease (CKD). The authors aimed define the status of in black 79 National Health Nutrition Examination Survey 2005–2012 provide practical guidance. Black patients were more often aware treated ( P ≤.005) than whites had higher rates DM/CKD <.001), similar control <140/<90 with =.59), lower...
Monoclonal immunoglobulin deposition disease (MIDD) is a rare disease, usually manifesting between the 5(th) and 6(th) decades of life but can also occur earlier. Characteristic feature MIDD non-fibrillar, Congo red negative monoclonal immunoglobulins in various organs, including kidneys. Depending on composition deposits, classified into 3 types; light chain (LCDD), which most common form, heavy (HCDD) (LHCDD). Kidney involvement MIDD. Renal biopsy reveals nodular sclerosing glomerulopathy...
Patient Male, 32 FINAL DIAGNOSIS: Dural arterio-venous fistula Symptoms: Eye redness • post-trauma headache tinnitus- Clinical Procedure: Fistula embolization Specialty: Neurology.Mistake in diagnosis.A dural arteriovenous (DAVF), is an abnormal direct connection (fistula) between a meningeal artery and vein or venous sinus. The pathogenesis of DAVF still remains unclear. Sinus thrombosis, head trauma, chronic central nervous system, hypercoagulable state, surgery, hormonal influence are the...
Background: Ethylene glycol ingestion can lead to acute kidney injury from tubular deposition of oxalate crystals. The diagnosis ethylene intoxication is based on a history ingestion, clinical examination, high anion gap metabolic acidosis, osmolal gap, and measured serum level glycol. However, depending the delay in time arrival hospital, may become normal, thereby creating confusing clinic picture for treating clinician. Case: A 71 year-old man with alcohol abuse had been unconscious an...
Key Points Tenapanor is a first-in-class, minimally systemic sodium–hydrogen exchanger 3 inhibitor with mechanism of action distinct from phosphate binders. alone or binders led to 35%–49% patients achieving serum ≤4.5 mg/dl over an 18-month period versus 22% at baseline. may help adults CKD on maintenance dialysis achieve normal concentrations. Background Most ESKD and hyperphosphatemia have difficulty controlling (sP) concentrations despite dialysis, dietary restriction, binder treatment....
Key Points In this phase 3b, noninferiority trial, vadadustat once daily was noninferior to darbepoetin alfa (DA) in the correction and maintenance of hemoglobin dialysis-dependent CKD. Vadadustat three times weekly treatment resulted similar changes mean levels compared with daily, but not DA. The safety profiles were comparable that Background is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor for treating anemia This study investigated efficacy once-daily three-times-weekly...
Acute tubular necrosis and pigment induced kidney injury are well described consequences of cocaine abuse. However, acute interstitial nephritis associated with use has been previously reported in only three patients.We present the case a 49-year-old man who developed from biopsy-proven after nasal insufflation cocaine. Unlike prior reports, our patient remained non-oliguric did not require renal replacement therapy.Interstitial should be considered as potential cause use. The approach to...
Cocaine is a potent sympathomimetic agent associated with the development of possible fatal cardiovascular complications. Dysrhythmias, acute myocardial infarction, hypertension and dilated cardiomyopathy are just some many effects related to abuse cocaine. A 38-year-old Hispanic male past medical history presented chief complaint progressive shortness breath. The patient confessed use cocaine for almost 18 years once per week. On examination he was hypertensive tachycardic systolic murmur...
Female, 50 FINAL DIAGNOSIS: Double superior vena cava Symptoms: -- Clinical Procedure: - Specialty: Nephrology.Anatomical anomaly/variation.Superior anomalies are caused by variations in the development of embryonic thoracic venous system. Duplication is a rare anomaly with an incidence general population 0.3%. The majority cases asymptomatic and diagnosed incidentally imaging done for another reason.A fifty year old female patient presented to our care history end stage renal disease that...
Male, 22 FINAL DIAGNOSIS: Cardiomyopathy Symptoms: Shortness of breath • dispnoea chest discomfort- Clinical Procedure: Echocardiogram cardiac MRI Specialty: Cardiology.Challenging differential diagnosis.Non-compaction cardiomyopathy (NCM) is a rare congenital characterized by increased trabeculation in one or more segments the ventricle. The left ventricle most commonly affected. However, biventricular involvement right predominance has also been described. features NCM are non-specific and...