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A5067649459
Research Areas
- Kruppel-like factors research
- Hippo pathway signaling and YAP/TAZ
Background: The transcription factor BACH1 (BTB and CNC homology 1) suppressed endothelial cells (ECs) proliferation migration impaired angiogenesis in the ischemic hindlimbs of adult mice. However, role underlying mechanisms atherosclerosis remain unclear. Methods: Mouse models cell (EC)-specific-Bach1 knockout mice were used to study regulation atherogenesis mechanisms. Results: Genetic analyses revealed that coronary artery disease-associated risk variant rs2832227 was associated with...
10.1161/circresaha.121.319540
article
EN
Circulation Research
2022-02-24
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