A5021713053- Gut microbiota and health
- Veterinary Medicine and Surgery
- Veterinary Oncology Research
- Human-Animal Interaction Studies
- Diet and metabolism studies
- Clostridium difficile and Clostridium perfringens research
- Vitamin D Research Studies
- Gastrointestinal motility and disorders
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Probiotics and Fermented Foods
- Parathyroid Disorders and Treatments
- Infant Nutrition and Health
- Intestinal and Peritoneal Adhesions
- Abdominal Trauma and Injuries
- Regulation of Appetite and Obesity
- Veterinary Equine Medical Research
- Urinary Tract Infections Management
- Gallbladder and Bile Duct Disorders
- Helminth infection and control
- Genetic Syndromes and Imprinting
- Pancreatitis Pathology and Treatment
- Urinary Bladder and Prostate Research
- Cardiovascular Conditions and Treatments
- Escherichia coli research studies
The Ohio State University
2016-2025
Dean College
2024
Nationwide Children's Hospital
2022-2023
North Carolina State University
2023
Texas A&M University
2023
Florida College
2023
University of Florida
2023
Ohio University
2018
Background: Chronic kidney disease (CKD) is associated with morbidity and mortality in dogs. Plasma fibroblast growth factor‐23 (FGF‐23) concentration an independent predictor of CKD progression survival cats people CKD. Objectives: To investigate the relationship among FGF‐23, parathyroid hormone (PTH), vitamin D metabolites, other clinical variables time dogs Animals: Twenty‐seven azotemic Methods: Dogs were recruited prospectively into study followed until death or conclusion....
ABSTRACT Background Insulin‐treated diabetic cats frequently achieve transient remission. The glucagon‐like peptide‐1 receptor agonist, exenatide extended‐release (exenatide‐ER), preserves β cell function in people with type 2 diabetes mellitus (DM). Objectives Investigate the effect of exenatide‐ER on duration remission cats. Animals Twenty‐two client‐owned recent remissions. Methods Placebo‐controlled, single‐blinded study. Cats were assigned randomly to receive (0.13 mg/kg) or saline...
To describe the clinical outcome of dietary management Yorkshire terriers with protein-losing enteropathy without immunosuppressive/anti-inflammatory medications.Records were searched for hypoalbuminaemia and a diagnosis that managed diet medications. Serum albumin changes compared using one-way repeated measures ANOVA. Canine chronic activity index scores Wilcoxon signed-rank test.Eleven cases identified. Clinical signs variable including: diarrhoea, respiratory signs, vomiting, lethargy...
Case series summary Cats with ionized hypercalcemia that were fed diets either more than 200 mg calcium per 100 kilocalories (kcal), a calcium:phosphorus (Ca:P) ratio greater 1.4:1 or both, based on diet history, included in this case series. Ionized was documented at least twice all cats before enrollment. referred for evaluation of (n = 5) incidentally found to have 5). After medical workups, diagnosed idiopathic (IHC; n 7) chronic kidney disease 3). receiving medications treat IHC (eg,...
Abstract Rodent models and human clinical studies have shown gut microbiota-derived short-chain fatty acids (SCFAs) play roles in obesity insulin resistance. These been minimally explored cats, where the USA an estimated 60% of cats are overweight or obese. Overweight/obese research (n = 7) were transitioned from a maintenance diet to reduced calorie fed ad libitum for 7 days, then calories restricted achieve 1–2% weight loss per week additional 77 days. Cats received their original again 14...
Objective To determine the agreement of canine faecal scoring between individuals with different levels experience using two available systems. Materials and Methods Naturally‐voided, undisturbed bowel movements from 126 dogs were evaluated by veterinarians (n = 3) members lay public 126) within 15 minutes defecation. Each participant was provided a copy Purina Waltham charts in order to characterise faeces. Agreement people assessed kappa statistics, Bland‐Altman analysis visualised plots....
To describe the outcome of dietary management canine noninfectious acute colitis with or without concurrent oral administration metronidazole using a randomized controlled clinical trial.59 client-owned dogs colitis.Dogs were enrolled in 30-day diet trial after exclusion parasitic infectious etiologies (fecal centrifugation floatation, Giardia/Cryptosporidium antigen testing) and systemic disease (CBC, biochemistry, urinalysis). Dogs into 3 placebo-controlled groups: group 1, easily...
Ancylostoma caninum is a nematode of the canine gastrointestinal tract commonly referred to as hookworm. This study involved eight privately owned adult greyhounds presenting with persistent A. ova shedding despite previous deworming treatments. The dogs received combination treatment protocol comprising topical moxidectin, followed by pyrantel/febantel/praziquantel within 24 hr. At 7-10 days posttreatment, fecal examination monitored for parasite ova. Dogs remained on monthly until they...
Dietary fiber describes a diverse assortment of nondigestible carbohydrates that play vital role in the health animals and maintenance gastrointestinal tract homeostasis. The main roles dietary include physically altering digesta, modulating appetite satiety, regulating digestion, acting as microbial energy source through fermentation. These functions can have widespread systemic effects. Fiber is component nearly all commercial canine feline diets. Key features types, such fermentability,...
Chronic inflammatory enteropathy (CE) is a common cause of persistent gastrointestinal signs and intestinal inflammation in dogs. Since evidence links dysbiosis to mucosal inflammation, probiotics, prebiotics, or their combination (synbiotics) may reduce ameliorate affected This study's aim was investigate the effects synbiotic-IgY supplement on clinical signs, indices, microbiota dogs with CE. Dogs CE were enrolled randomized prospective trial. Twenty-four client-owned fed hydrolyzed diet...
A 13-year-old male castrated Domestic Shorthair cat was presented for investigation of lethargy, vomiting, polydipsia and polyuria. Glucocorticoid-deficient hypoadrenocorticism suspected based on hypocholesterolaemia, hypoglycaemia lack a stress leucogram, confirmed with an ACTH stimulation test. Pituitary disease the clinical signs combination hyposthenuria hypernatraemia. Necropsy revealed bilaterally symmetric adrenocortical atrophy changes in pituitary gland were suggestive T-cell-rich...
Fecal diagnostics are a mainstay of feline medicine, and fecal identification markers help to distinguish individuals in multi-cat environment. However, the impact on microbiota unknown. Given increased interest using endpoints inform diagnosis treatment, objective this study was examine effects orally supplemented glitter crayon shavings (amplicon sequencing 16S rRNA gene V4 region). samples were collected daily from six adult cats that randomized receive oral supplementation with either or...
Urine specific gravity (USG) is an integral part of the urinalysis and a key component many clinical decisions, fluctuations in USG have potential to impact case management.To determine intraindividual variability first morning results healthy dogs.One hundred three client-owned dogs.Dogs were deemed based on history physical examination findings. Repeated measurements performed over course 2 weeks. Three urine samples collected each week for total 6 per dog. Sample collection was...
Abstract Background Chronic kidney disease‐mineral and bone disorder (CKD‐MBD) in dogs is associated with hypovitaminosis D, increased parathyroid hormone (PTH), fibroblast growth factor‐23 (FGF‐23) concentrations. Best practice for vitamin D metabolite supplementation CKD‐MBD remains unknown. Objective To provide an extended‐release calcifediol supplement to CKD measure its effects on variables indicative of CKD‐MBD. Animals Ten International Renal Interest Society stages 2 3 CKD. Methods...
Objectives Changes in bowel movements (BMs) are an important clinical sign many diseases, including chronic kidney disease (CKD), and the purpose of this study was to collect information on BMs fecal scores both apparently healthy CKD cats. A secondary aim assess owner awareness BM frequency. Methods Owners were asked complete initial online questionnaire about their cat’s health litter box habits (including predicted frequency scores) then clean daily for 7 days report results (observed...
Abstract Objective To characterize clinician preferences and justification for preferred methods managing canine idiopathic acute diarrhea (IAD) compare results to evidence-based literature. sample 284 surveys from veterinarians in small animal first-opinion practice. Methods Veterinarians were asked complete a survey (61 questions) including background demographic information, practice type location, duration practice, management questions IAD pertaining nutritional, probiotic,...