A5024097225- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial biofilms and quorum sensing
- Advanced Drug Delivery Systems
- Bone Tissue Engineering Materials
- Bacteriophages and microbial interactions
- Salmonella and Campylobacter epidemiology
- Vibrio bacteria research studies
- Nanoparticle-Based Drug Delivery
- Radioactive element chemistry and processing
- Crystal Structures and Properties
- Bacterial Genetics and Biotechnology
- Luminescence Properties of Advanced Materials
- Medicinal Plants and Neuroprotection
- Infections and bacterial resistance
- Nanoparticles: synthesis and applications
- Polymer Surface Interaction Studies
- Drug Solubulity and Delivery Systems
- GABA and Rice Research
- Viral gastroenteritis research and epidemiology
- Neutropenia and Cancer Infections
- Monoclonal and Polyclonal Antibodies Research
- Seed and Plant Biochemistry
- Enzyme function and inhibition
- Antimicrobial agents and applications
University of Wrocław
2011-2023
Bacteriophage KP34 is a novel virus belonging to the subfamily Autographivirinae lytic for extended-spectrum β-lactamase-producing Klebsiella pneumoniae strains. Its biological features, morphology, susceptibility chemical and physical agents, burst size, host specificity activity spectrum were determined. As potential antibacterial agent used in therapy, molecular features including genome sequence protein composition examined. Phylogenetic analyses clustering of phage sequences revealed...
The Eu3+ and Sr2+ ions co-doped hydroxyapatite nanopowders (Ca10(PO4)6(OH)2) were synthesized via a precipitation method post heat-treated at 500 °C. concentration of was established in the range 0.5–5 mol% to investigate site occupancy preference. set 5 mol%. structural morphological properties obtained materials studied by an X-ray powder diffraction, transmission electron microscopy techniques infrared spectroscopy. As nanoparticles 11–17 nm annealed particles 20–26 nm. luminescence...
Different metals, such as silver (Ag), copper (Cu), and zinc (Zn), have been broadly investigated metals cations used both in medicine everyday life due to their broad spectrum of antibacterial activity. Although the action those ions is well known studied, main problem remains standardization experimental procedures determine antimicrobial activity bacteriological media composition might significantly influence outcome. The presented study aimed evaluate appropriability different culture...
The implementation of non-traditional antibacterials is currently one the most intensively explored areas modern medical and biological sciences. One promising alternative strategies to combat bacterial infections application lytic phages combined with established new antibacterials. presented study investigates potential agarose-based biocomposites containing Pseudomonas (KT28, KTN4, LUZ19), cupric ions (Cu2+), strawberry furanone (HDMF), gentamicin (GE) as anti-virulent compounds for novel...
The antimicrobial activity of eight cationic, two neutral and three anionic liposome compositions containing meropenem gentamicin was tested in vitro broth serum medium. cationic formulations showed better antibacterial efficacy against both Gram-positive Gram-negative bacteria than the ones, regardless encapsulated drug. most effective were PC/DOPE/DOTAP 3:4:3 PC/Chol/DOTAP 3:4:3, as MICs with 2 to 4 times lower those free
The antimicrobial activity of two cationic liposomes containing three antibiotics were tested in vitro. Ciprofloxacin loaded exhibited a 2-4 times higher compared with the free drug. bacterial sensitivity to liposomal meropenem similar as antibiotic. least effective gentamicin.
The antibiotic resistance of pathogenic microorganisms is a worldwide problem. Each year several million people across the world acquire infections with bacteria that are antibiotic-resistant, which costly in terms human health. New antibiotics extremely needed to overcome current Transgenic flax plants overproducing compounds from phenylpropanoid pathway accumulate phenolic derivatives potential antioxidative, and thus, antimicrobial activity. Alkali hydrolyzed seedcake extract containing...
Li+/Eu3+ dual-doped calcium apatite analogues were fabricated using a microwave stimulated hydrothermal technique. XRPD, FT-IR, micro-Raman spectroscopy, TEM and SAED measurements indicated that obtained apatites are single-phased, crystallize with hexagonal structure, have similar morphology nanometric size as well show red luminescence. Lithium effectively modifies the local symmetry of optical active sites and, thus, affects emission efficiency. Moreover, hydrodynamic surface charge...
Multifunctional nanocrystalline chlorapatites doped with lanthanide ions (Eu<sup>3+</sup>, Er<sup>3+</sup>and Yb<sup>3+</sup>) and co-doped silver were synthesized by a hydrothermal synthesis route studied.
Abstract The proposed research outlines a serious common concern of Salmonella resistance to antimicrobials following prolonged exposure the disinfectants (biocides). These phenotypes bacteria could potentially result in hard treat infections. Typical for avian sources, biocide sensitive S. enterica subsp. serovars: Typhimurium, Enteritidis, Virchow and Zanzibar their isogenic biocide-tolerant variants were studied order investigate bacteriostatic effect two commercially available...
The O48 group comprises Salmonella bacteria containing sialic acid in the lipopolysaccharide (LPS). Bacteria with sialylated surface structures are described as pathogens that avoid immunological response of host by making similar their antigens to host's tissues (molecular mimicry). It is known smooth-type LPS enterica and outer membrane proteins (OMP) PgtE, PagC Rck mediate serum resistant phenotype affecting complement system (C). aim this study was investigate C3 component activation...
In this study, we investigated the anti-pseudomonal activity of cupric ions (Cu2+), strawberry furanone (HDMF), gentamicin (GE), and three lytic Pseudomonas aeruginosa bacteriophages (KT28, KTN4, LUZ19), separately in combination. HDMF showed an anti-virulent effect but only when applied with Cu2+ or GE. GE, at a sub-minimal inhibitory concentration, slowed down phage progeny production due to protein synthesis inhibition. significantly reduced both bacterial cell count number infective...