A5048704699- Thyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Geriatric Care and Nursing Homes
- Vitamin D Research Studies
- Education, Psychology, and Social Research
- Bone health and osteoporosis research
- Hypothalamic control of reproductive hormones
- Growth Hormone and Insulin-like Growth Factors
- Nursing education and management
- Pregnancy and preeclampsia studies
- Global Health Care Issues
- Frailty in Older Adults
- Crop Yield and Soil Fertility
- Medication Adherence and Compliance
- Nursing Diagnosis and Documentation
- Healthcare Systems and Reforms
- Inflammatory Bowel Disease
- Cell Adhesion Molecules Research
- Neuroendocrine Tumor Research Advances
- Entomological Studies and Ecology
- Head and Neck Anomalies
- Biomarkers in Disease Mechanisms
- Cancer Risks and Factors
- Diagnosis and Treatment of Venous Diseases
University of Basel
2021-2024
Charles University
1979-2021
Apigenex (Czechia)
2018-2019
General University Hospital in Prague
2016-2018
The guidelines of American Thyroid Association from 2011 include age over 30 as one the risk factors for hypothyroidism in pregnancy.Our objective was to verify whether increases autoimmune thyroid disease pregnancy.We performed a cross-sectional study 2006-2008 with laboratory assessment single center using primary care gynecological ambulances cooperation referral center.The included 5223 consecutive pregnant women gestational wk 9-12.We assessed occurrence pathological serum...
Unplanned nursing home (NH) transfers are burdensome for residents and costly health systems. Innovative nurse-led models of care focusing on improving in-house geriatric expertise needed to decrease unplanned transfers. The aim was test the clinical effectiveness a comprehensive, contextually adapted model (INTERCARE) in reducing from NHs hospitals.A multicenter nonrandomized stepped-wedge design within hybrid type-2 effectiveness-implementation study implemented 11 German-speaking...
Abstract Background While effectiveness outcomes of eHealth-facilitated integrated care models (eICMs) in transplant and oncological populations are promising, implementing sustaining them real-world settings remain challenging. Allogeneic stem cell (alloSCT) patients could benefit from an eICM to enhance health outcomes. To combat deterioration, integrating chronic illness management, including continuous symptom behaviour monitoring, can shorten reaction times. We will test the 1st-year...
The relationship between Hashimoto’s thyroiditis (HT) and thyroid cancer (TC) is a controversial topic; it remains unclear if HT acts as risk factor of TC. aim our study was to compare the presence function in patients with TC benign nodules. We analyzed 2571 after fine needle aspiration biopsy nodule. Totally, 91 primary 182 sex- age-matched controls were included. Positive antithyroid peroxidase (anti-TPO) antithyroglobulin (anti-Tg) antibodies associated (anti-TPO 44% vs. 27% controls,...
Summary Objective Iodine deficiency is associated with thyroid dysfunction and adverse pregnancy outcomes. The aim of our study was to investigate the status iodine saturation in women after spontaneous abortion ( S p A ) residing an iodine‐sufficient area evaluate their subsequent reproductive health. Design Nonrandomized prospective follow‐up study. Patients methods We compared urinary concentration UIC 171 2–8 weeks (median 4) early age‐matched controls. Women known diseases were...
Hypothyroidism and/or autoimmune thyroid disorders (AITD) may contribute to spontaneous abortions (SpA). Cost-effectiveness analyses of screening in women after SpA are lacking. Our aim was evaluate the cost-effectiveness for AITD hypothyroidism and their treatment with regard reproductive health. We performed a cross-sectional non-randomized study follow-up 2008–2011 settings Departments Endocrinology Obstetrics/Gynecology university hospital. enrolled 258 before 12th gestational week...
Abstract It is controversial whether screening program for thyroid disorders in pregnancy should be universal or targeted case-finding. To evaluate the relationship between history, laboratory parameters and ultrasound (TUS) pregnant women positive screening. The included investigation of serum TSH (thyroid stimulating hormone) TPOAb (antithyroperoxidase antibodies) 5 520 unselected 9–11th gestational week. In 822 was positive: abnormal (> 3.67 < 0.06 mIU/l) and/or 143 kIU/l). 200...
Abstract Background Health economic evaluations of the implementation evidence-based interventions (EBIs) into practice provide vital information but are rarely conducted. We evaluated health impact associated with and intervention INTERCARE model—an EBI to reduce hospitalisations nursing home (NH) residents—compared usual NH care. Methods The model was conducted in 11 NHs Switzerland. It implemented as a hybrid type 2 effectiveness-implementation study multi-centre non-randomised...
The diagnostic and prognostic role of thyroid ultrasound (TUS) in pregnant women positive for antibodies to thyroperoxidase (TPOAb) is unclear. aim our study was compare the relation texture laboratory tests controls. Using a semi-quantitative assessment we compared TUS two groups with TPOAb and/or dysfunction (TSH out 0.06-3.67 mIU/L): 186 1st trimester pregnancy recruited from universal screening 67 asymptomatic age-comparable non-pregnant non-postpartum general population (controls)....
Functional deficiency of mannan-binding lectin (MBL) has been associated with adverse pregnancy outcome. Adverse events during have also described in women autoimmune thyroid diseases (AITD), and hormones shown to influence serum levels MBL. Therefore, the aim this study was analyse impact MBL-deficiency on outcome relation presence AITD. Almost one year after delivery, we assessed MBL MBL2-genotypes 212 positively screened for AITD pregnancy. In 103 these women, could measure frozen samples...
Summary Anti-C1q antibodies (anti-C1q) have been implicated in the pathogenesis of autoimmune diseases, including thyroid disorders (AITD). The aim this study was to evaluate association between anti-C1q and function pregnancy-associated AITD. In 96 pregnant women screened positive for AITD (thyroid dysfunction and/or against thyroperoxidase – TPOAb), were measured during 9-11th gestational week after delivery (median 16 months delivery), compared corresponding serum levels hormones. As...
Measurement of thyroid nodule stiffness by strain elastography already showed promising results. The aim our study was to evaluate the diagnostic performance in predicting cancer determination ratio comparing with tissue and surrounding neck tissues as well (carotid artery, muscles). Totally, 310 nodules 275 patients were examined conventional ultrasound prior aspiration biopsy. 22(7.1%) carcinomas histologically confirmed included study. 39 benign (27 histology 12 cytology at least 2 years...
<sec> <title>BACKGROUND</title> Nursing-sensitive events (NSEs) are common, accounting for up to 77% of adverse in hospitalized patients (eg, fall-related harm, pressure ulcers, and health care–associated infections). NSEs lead patient outcomes impose an economic burden on hospitals due increased medical costs through a prolonged hospital stay additional procedures. To reduce ensure high-quality nursing care, appropriate nurse staffing levels needed. Although the link between has been...
Nursing-sensitive events (NSEs) are common, accounting for up to 77% of adverse in hospitalized patients (eg, fall-related harm, pressure ulcers, and health care-associated infections). NSEs lead patient outcomes impose an economic burden on hospitals due increased medical costs through a prolonged hospital stay additional procedures. To reduce ensure high-quality nursing care, appropriate nurse staffing levels needed. Although the link between has been described many studies, lacking....
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)