A5029718977- Health Policy Implementation Science
- Medication Adherence and Compliance
- Health Systems, Economic Evaluations, Quality of Life
- Community Health and Development
- Renal Transplantation Outcomes and Treatments
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Neutropenia and Cancer Infections
- COVID-19 and healthcare impacts
- Delphi Technique in Research
- Cerebral Venous Sinus Thrombosis
- Heart Failure Treatment and Management
- Health Sciences Research and Education
- Evaluation and Performance Assessment
- HIV/AIDS Research and Interventions
- Geriatric Care and Nursing Homes
- Patient-Provider Communication in Healthcare
- Health and Medical Studies
- Economic and Financial Impacts of Cancer
- Adolescent and Pediatric Healthcare
- Patient Satisfaction in Healthcare
- Hematopoietic Stem Cell Transplantation
- Environmental and Social Impact Assessments
- Cardiac, Anesthesia and Surgical Outcomes
- Interprofessional Education and Collaboration
Leipzig University
2025
University of Basel
2019-2024
Swiss School of Public Health
2024
Abstract Background Designing intervention and implementation strategies with careful consideration of context is essential for successful science projects. Although the importance has been emphasized methodology its analysis emerging, researchers have little guidance on how to plan, perform, report contextual analysis. Therefore, our aim was describe Basel Approach coNtextual ANAlysis (BANANA) demonstrate application an ongoing multi-site, multiphase project develop/adapt, implement,...
Context in implementation science includes not only characteristics of a setting which an intervention will be delivered, but also social systems (e.g., interrelationships). is dynamic and interacts with both, the its implementation. Therefore, contextual analysis recognized as indispensable part methodology: it provides foundation for successful sustainable projects. Yet, driven by prevailing post-positivist understanding context, typically focuses on individual context i.e., dynamics...
Introduction Venous thromboembolic events (VTEs) like deep vein thrombosis or pulmonary embolism are frequent complications in (neuro) critical ill patients. Anticoagulation for VTE after space-occupying brain infarction is a therapeutic dilemma. The aim of this retrospective study was to investigate the frequency clinically apparent patients with acute ischaemic stroke (AIS) due large vessel occlusion (LVO), its treatment, and rate complications. Methods Patients first AIS LVO were assigned...
Abstract Background Medication adherence to immunosuppressants in allogeneic stem cell transplantation (alloSCT) is essential achieve favorable clinical outcomes (e.g. control of Graft-versus-Host Disease). Over 600 apps supporting medication exist, yet they lack successful implementation and sustainable use likely because end-user involvement theoretical underpinnings their development insufficient attention methods support real-life settings. has three phases: initiation , persistence . We...
Allogeneic stem cell transplantation would benefit from re-engineering care towards an integrated eHealth-facilitated model. With this paper we aim to: (1) describe the development of model (ICM) in allogeneic SteM-cell-transplantatIon faciLitated by eHealth (SMILe) combining implementation, behavioral, and computer science methods (e.g., contextual analysis, Behavior Change Wheel, user-centered design combined with agile software development); (2) that model's characteristics its...
Within implementation science studies, contextual analysis is increasingly recognized as foundational to interventions' successful and sustainable implementation. However, inconsistencies between methodological approaches currently limit progress in studying context guidance standardize the use of those scant. Therefore, this study's objective was systematically review map current intervention studies. The results would help us both systematize process identify gaps evidence.We conducted an...
Abstract Background While effectiveness outcomes of eHealth-facilitated integrated care models (eICMs) in transplant and oncological populations are promising, implementing sustaining them real-world settings remain challenging. Allogeneic stem cell (alloSCT) patients could benefit from an eICM to enhance health outcomes. To combat deterioration, integrating chronic illness management, including continuous symptom behaviour monitoring, can shorten reaction times. We will test the 1st-year...
Contextually adapting complex interventions and tailoring their implementation strategies is key to a successful sustainable implementation. While reporting guidelines for adaptations exist, less known about how conduct context-specific of health care interventions.To describe in methodological terms the merging contextual analysis results (step 1) with stakeholder involvement, considering overarching regulations 2) informed our adaptation an Integrated Care Model (ICM) SteM cell...
eHealth-facilitated integrated care models (eICMs) have proved effective in improving outcomes for chronically ill patients. However, evidence on cost-effectiveness of eICMs is scarce so far. Allogeneic stem cell transplantation (alloSCT) recipients' post-discharge treatment costs and mortality are greatly influenced by complications. Within the international, multicentric SMILe implementation science project, model (SMILe-ICM) was developed to support patients minimize complications'...
High performance work systems (HPWSs) are successful in the context of safety climate and patient safety. The 10-item HPWS questionnaire is a validated instrument developed to assess existing structures hospitals. objectives this cross-sectional study were translate English into German (HPWS-G), rate its content validity, examine psychometric properties. Content validity was examined by panel 12 physicians nurses, I-CVI S-CVI calculated. For internal consistency, Cronbach's α item-scale...
In implementation science (IS), conducting well-targeted and reproducible literature searches is challenging due to non-specific varying terminology that fragmented over multiple disciplines. A list of journals publish IS-relevant content for use in search strings can support this process. We conducted a cross-sectional online survey 56 Australian, European, North American IS experts identify prioritize relevant articles. Journals' relevance was assessed by providing each with 12 journals,...
Social support is critical in follow-up of patients after heart transplant (HTx) and positively influences well-being clinical outcomes such as medication adherence. The purpose this study was to (i) explore received social variation (emotional practical) HTx recipients at country centre level (ii) assess multi-level correlates.Secondary data analysis the cross-sectional BRIGHT conducted 36 centres 11 countries. Received related adherence measured with emotional practical sub-scales....
A trustful relationship between transplant patients and their team (interpersonal trust) is essential in order to achieve positive health outcomes behaviors. We aimed 1) explore variability of trust teams; 2) the association level chronic illness management trust; 3) investigate on behavioral outcomes. secondary data analysis BRIGHT study (ID: NCT01608477; https://clinicaltrials.gov/ct2/show/NCT01608477?id=NCT01608477&rank=1 ) was conducted, including multicenter from 36 heart...
Trust is associated with better patient outcomes, such as medication adherence and improved satisfaction. However, the association between trust level of chronic illness management (CIM) has not yet been addressed. We assessed hypothesis that CIM will be in HTx team. Additionally, we explored potential meso-level moderators this relationship (time spent on visits, number multidisciplinarity, competencies, preparedness healthcare team). A secondary analysis was conducted using international...
Introduction: Social support is critical in follow-up of patients after heart transplant (HTx) and positively influences well-being clinical outcomes. Hypothesis: The purpose this secondary analysis was to 1) explore received social variation HTx-recipients at country center level (emotional practical) 2) assess patient-, micro-, meso- macro-level correlates. Methods: We examined data from the multi-level cross-sectional BRIGHT study, conducted 36 HTx-centers 11 countries. used an 11-item...