A5001182395- Environmental Toxicology and Ecotoxicology
- Trace Elements in Health
- Heavy metals in environment
- Heavy Metal Exposure and Toxicity
- Bacteriophages and microbial interactions
- CAR-T cell therapy research
- Mercury impact and mitigation studies
- Monoclonal and Polyclonal Antibodies Research
- Mollusks and Parasites Studies
- Environmental DNA in Biodiversity Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Heavy Metals in Plants
- Fish Ecology and Management Studies
- Coccidia and coccidiosis research
- Respiratory viral infections research
- Carcinogens and Genotoxicity Assessment
- Nanoparticles: synthesis and applications
- Microplastics and Plastic Pollution
- Viral Infections and Vectors
- Plant Genetic and Mutation Studies
- Aquatic Invertebrate Ecology and Behavior
- Virus-based gene therapy research
- Bird parasitology and diseases
- Aquaculture Nutrition and Growth
- Bat Biology and Ecology Studies
Université de franche-comté
2012-2017
Laboratoire Chrono-Environnement
2014-2016
Centre National de la Recherche Scientifique
2012-2016
Université Bourgogne Franche-Comté
2016
The aim of this study was to analyze the expression three metallothionein (MT) isoform genes (CdMT, CuMT and Cd/CuMT), already known from adults, in Early Life Stage (ELS) Cantareus aspersus. This accomplished by detection MT isoform-specific transcription adopting Polymerase Chain Reaction (PCR) amplification quantitative Real Time (qRT)-PCR genes. Freshly laid eggs were kept for 24 hours under control conditions or exposed cadmium (Cd) solutions increasing concentration (5, 10, 15 mg...
While the lesser horseshoe bat (Rhinolophus hipposideros) was common in most western and Central Europe, this species endured a dramatic decline 1950s–1970s. The causes are thought to comprise extensive spread of chemical pollutants affecting both prey populations, changes landscape composition structure leading population fragmentation or roost deterioration, infectious diseases. populations recently increased after nearly thirty years Franche-Comté region (eastern France), it is unclear...
Cadmium (Cd) can be toxic to terrestrial snails, but few data are available about its genotoxic effects on early life stages (ELS). The aim of this study was investigate the potential Cd in embryos Helix aspersa using a new approach that couples Random Amplified Polymorphic DNA (RAPD) and high-resolution capillary electrophoresis system (HRS). Clutches H. were exposed solutions (2, 4, 6 mg/L) from beginning their embryonic development. In addition dose-dependent effect hatching rate,...
Metal regulation is essential for terrestrial gastropods to survive. In helicid snails, two metal-selective metallothionein (MT) isoforms with different functions are expressed. A cadmium-selective isoform (CdMT) plays a major role in Cd2 + detoxification and stress response, whereas copper-selective MT (CuMT) involved Cu homeostasis hemocyanin synthesis. third, non-metal-selective isoform, called Cd/CuMT, was first characterized Cantareus aspersus. The aim of this study quantify the...
Human respiratory syncytial virus (hRSV) is one of the major contagious viruses and causes complicated issues, especially in young children. The sensitive fast detection hRSV critical for taking most effective actions. In present study, rabbit antibodies against nucleoprotein (NP) were developed using phage display technology. A female was immunized with an strain A2 recombinant NP. Fab library built sorted during two successive panning rounds B NP (recombinant preparations), respectively....
The human leucine-rich repeat-containing protein 15 (LRRC15) is a membrane identified as marker of CAF (cancer-associated fibroblast) cells whose overexpression positively correlated with cancer grade and outcome. Nuclear molecular imaging (i.e., SPECT PET) to track LRRC15 expression could be very useful in guiding further therapeutic strategies. In this study, we developed an ScFv mouse phage-display library obtain small fragment antibodies against for purposes. Mice were immunized...