Purnika Damindi Ranasinghe

ORCID: 0000-0001-5413-2197
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About
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Research Areas
  • Microbial Community Ecology and Physiology
  • Wastewater Treatment and Nitrogen Removal
  • Gut microbiota and health
  • Infant Nutrition and Health
  • Tuberculosis Research and Epidemiology
  • Gastrointestinal motility and disorders
  • Mycobacterium research and diagnosis
  • Oral microbiology and periodontitis research
  • Diet and metabolism studies
  • Insect Utilization and Effects
  • Eosinophilic Esophagitis
  • Magnetic and Electromagnetic Effects
  • Insect symbiosis and bacterial influences
  • Infant Health and Development
  • Spaceflight effects on biology
  • Genomics and Phylogenetic Studies
  • Geomagnetism and Paleomagnetism Studies
  • Infectious Diseases and Tuberculosis
  • Microbial Fuel Cells and Bioremediation
  • Water Treatment and Disinfection
  • Asthma and respiratory diseases
  • Microbial infections and disease research

Agri Food and Biosciences Institute
2024-2025

Queen's University Belfast
2021

Linköping University
2018-2021

Environmental Earth Sciences
2016

Queensland University of Technology
2016

The University of Tokyo
2012

Abstract In utero and upon delivery, neonates are exposed to a wide array of microorganisms from various sources, including maternal bacteria. Prior studies have proposed that the mode feeding shapes gut microbiota and, subsequently child’s health. However, effect its influence on development neonatal oral in early infancy has not yet been reported. The aim this study was compare healthy infants were exclusively breast-fed or formula-fed using 16S-rRNA gene sequencing. We demonstrated...

10.1038/srep38309 article EN cc-by Scientific Reports 2016-12-06

Extremely low birth weight (ELBW) infants often develop an altered gut microbiota composition, which is related to clinical complications, such as necrotizing enterocolitis and sepsis. Probiotic supplementation may reduce these modulation of the microbiome a potential mechanism underlying probiotic effectiveness. In randomized, double-blind, placebo-controlled trial, we assessed effect Lactobacillus reuteri supplementation, from post-menstrual week (PMW)36, on infant microbiota. We performed...

10.1016/j.xcrm.2021.100206 article EN cc-by Cell Reports Medicine 2021-02-23

The microbial population in a laboratory activated sludge reactor was monitored for 245 d at 75 time points by pyrosequencing of 16S rRNA. Synthetic wastewater used as the influent, and operated under same conditions throughout experiment. behaviors different bacterial operational taxonomic units (OTUs) were observed. Multiple OTUs showed periodic propagation recession. One sharp recession, which suggests that cells OTU selectively killed. phylogenetic lineages Candidatus 'Accumulibacter...

10.1264/jsme2.me12115 article EN Microbes and Environments 2012-10-25

Mycobacterium bovis the main agent of bovine tuberculosis (bTB), presents as a series spatially-localised micro-epidemics across landscapes. Classical molecular typing methods applied to these micro-epidemics, based on genotyping few variable loci, have significantly improved our understanding potential epidemiological links between outbreaks. However, they limited utility owing low resolution. Conversely, whole-genome sequencing (WGS) provides highest resolution data available for...

10.1099/mgen.0.001185 article EN cc-by Microbial Genomics 2024-02-14

Abstract Eosinophils have been linked to functional dyspepsia; however, less is known about their role in irritable bowel syndrome (IBS). This study tested the hypothesis of alterations levels fecal eosinophil-derived neurotoxin (F-EDN) and eosinophil density degranulation within colonic mucosa IBS patients compared with healthy controls (HC). Colonic biopsies were collected from 37 20 HC analyzed for numbers local cationic protein (ECP) by histologic procedures. Fecal samples F-EDN...

10.1002/jlb.4a0521-228r article EN cc-by Journal of Leukocyte Biology 2021-06-21

The diversity of bacterial groups in activated sludge from large- and small-scale wastewater treatment plants was explored by barcoded pyrosequencing 16S rRNA gene. Activated samples (three small 17 large scale) were collected 12 to clarify precise taxonomy relative abundances. DNA extracted, amplified 4 base 27f/519r primer set. 454 Titanium (Roche) pyrosequences obtained analyses performed Quantitative Insight Into Microbial Ecology (QIIME) with around 100,000 reads. Sequence statistics...

10.2166/wst.2012.428 article EN Water Science & Technology 2012-09-05
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