A5033139894- Cytomegalovirus and herpesvirus research
- Genomics, phytochemicals, and oxidative stress
- Herpesvirus Infections and Treatments
- Milk Quality and Mastitis in Dairy Cows
- Reproductive Physiology in Livestock
- Animal Disease Management and Epidemiology
- Genetic and phenotypic traits in livestock
- Immune Response and Inflammation
- NF-κB Signaling Pathways
- Viral Infections and Vectors
- Toxoplasma gondii Research Studies
- Microbial infections and disease research
- Animal health and immunology
- Endoplasmic Reticulum Stress and Disease
- Immune Cell Function and Interaction
- Animal Virus Infections Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Vector-Borne Animal Diseases
- Viral-associated cancers and disorders
- Medicinal Plant Pharmacodynamics Research
- Veterinary Equine Medical Research
- Plant Virus Research Studies
- IL-33, ST2, and ILC Pathways
- Autophagy in Disease and Therapy
- Neonatal Health and Biochemistry
Liaocheng University
2022-2025
Equine herpesvirus type 8 (EHV-8) causes abortion and respiratory disease in horses donkeys, leading to serious economic losses the global equine industry. Currently, there is no effective vaccine or drug against EHV-8 infection, underscoring need for a novel antiviral prevent EHV-8-induced latent infection decrease pathogenicity of this virus. The present study demonstrated that hyperoside can exert effects RK-13 (rabbit kidney cells), MDBK (Madin-Darby bovine kidney), NBL-6 cells (E. Derm...
Equine herpesvirus-1 (EHV-1) is a significant pathogen that causes substantial economic losses in the equine industry worldwide, which leads to severe respiratory diseases and abortions horses. However, reports of EHV-1 infection donkeys are limited, particularly China. This case study reported an EHV-1-induced disease Dezhou donkey foals Shandong Province, China, July 2024. Three one-month-old exhibited high fever, nasal discharge, distress, with 100% mortality rate. The causative agent,...
Present study was designed to investigate the potential role of inhibin immunization on plasma hormone concentration and testicular histoarchitecture Dezhou donkeys in non breeding season (November-February). For this purpose, adult (n=30), were equally divided into groups A, B, C. Group A actively immunized with 3 mg inhibin, group B (1.5 mg), C Bovine serum albumin (BSA) served as a control. All animals given primary dose (INH) antigen i.e. 1.5 day 1 followed by booster 23rd experiment....
The present study was designed to investigate the potential role of inhibin immunization on plasma hormone concentration and testicular histoarchitecture Dezhou donkeys in nonbreeding season (November–February). For this purpose, adult (n = 30) were equally divided into groups A, B, C. Group A actively immunized with 3 mg inhibin, group B (1.5 mg), C Bovine serum albumin (BSA) served as a control. All animals given primary dose (INH) antigen, i.e., 1.5 day 1, followed by booster 23rd...
Abstract Background Equine herpesvirus-8 (EHV-8) is one of the most economically significant viruses that infect mammals genus Equus worldwide, which cause severe respiratory diseases and abortion in horses. However, there no report caused by EHV-8 donkeys. Case presentation The present case about a 4-year-old donkey having an showing serious issue on 296th day pregnancy. Bacteriological molecular tests were used to screen possible bacterial/viral pathogens detect etiological agent....
ABSTRACT Equid alphaherpesvirus 8 (EqHV-8) is one of the most economically important viruses that known to cause severe respiratory disease, abortion, and neurological syndromes in equines. However, no effective vaccines or therapeutic agents are available control EqHV-8 infection. Heme oxygenase-1 (HO-1) an antioxidant defense enzyme displays significant cytoprotective effects against different viral infections. literature on function HO-1 during infection little. We explored revealed its...
Equid herpesvirus type 8 (EqHV-8) is known to cause respiratory disease and miscarriage in horses donkeys, which a major problem for the equine farming industry. However, there are currently limited vaccines or drugs available effectively treat EqHV-8 infection. Therefore, it crucial develop new antiviral approaches prevent potential pandemics caused by EqHV-8. This study evaluates antioxidant effects of cepharanthine against employing both vitro assays vivo mouse models assess its...
Equid herpesvirus type 8 (EqHV-8) poses a significant threat to equine health, leading miscarriages and respiratory diseases in horses donkeys, results substantial economic losses the donkey industry. Currently, there are no effective drugs or vaccines available for EqHV-8 infection control.
Viral infection causes endoplasmic reticulum stress and protein metabolism disorder, influencing aggregates formation or degradation that originate from misfolded proteins. The mechanism by which host proteins are involved in the above process remains largely unknown. present study found porcine reproductive respiratory syndrome virus (PRRSV) promoted of intracellular ubiquitinated via activating autophagy. cell E3 ligase tripartite motif-containing (TRIM)25 recruitment aggregation...