A5082146406- Gut microbiota and health
- Diet and metabolism studies
- Tryptophan and brain disorders
- Tea Polyphenols and Effects
- Dietary Effects on Health
Guangxi Medical University
2024
Sun Yat-sen Memorial Hospital
2023
Sun Yat-sen University
2023
BGI Group (China)
2020
Objective Intermittent energy restriction (IER) is an effective weight loss strategy. However, little known about the dynamic effects of IER on brain-gut-microbiome axis. Methods In this study, a total 25 obese individuals successfully lost after 2-month intervention. FMRI was used to determine activity brain regions. Metagenomic sequencing performed identify differentially abundant gut microbes and pathways in from fecal samples. Results Our results showed that longitudinally reduced...
Abstract Calorie restriction (CR) has been widely recognized for its effect in reducing body weight and alleviating diabetes humans, as well prolonging life span animal studies. Gut microbiome shifts contribute to part of the effects CR, but little is known regarding their influences except on metabolism immunity. Here we monitored gut using metagenomics metatranscriptomics obese individuals undergoing revealed microbial determinants that could successful loss. Microbiome changes are linked...