A5065634851- Nanoparticle-Based Drug Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Electrochemical sensors and biosensors
- Advanced Drug Delivery Systems
- Advanced Chemical Sensor Technologies
- Nanocluster Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Drug Solubulity and Delivery Systems
- Neuropeptides and Animal Physiology
- Anesthesia and Neurotoxicity Research
- Dye analysis and toxicity
- Protein Interaction Studies and Fluorescence Analysis
- Analytical Chemistry and Chromatography
- Social Media in Health Education
- Electrochemical Analysis and Applications
- Analytical Chemistry and Sensors
- Helicobacter pylori-related gastroenterology studies
- Identification and Quantification in Food
- Digital Marketing and Social Media
- Electrospun Nanofibers in Biomedical Applications
- Ultrasound and Hyperthermia Applications
- Phytochemicals and Antioxidant Activities
- Diverse Scientific Research in Ukraine
- Phytochemicals and Medicinal Plants
- Dyeing and Modifying Textile Fibers
University of Chile
2019-2024
Advanced Center for Chronic Diseases
2018-2023
Centro de Estudios Científicos
2021
Pontificia Universidad Católica de Chile
2021
Universidad Andrés Bello
2018-2020
University of the Amazon
2014-2015
Niclosamide (NICLO) is a recognized antiparasitic drug being repositioned for Helicobacter pylori. The present work aimed to formulate NICLO nanocrystals (NICLO-NCRs) produce higher dissolution rate of the active ingredient and incorporate these nanosystems into floating solid dosage form release them stomach slowly. For this purpose, NICLO-NCRs were produced by wet-milling included in Gelucire l3D printed tablet semi-solid extrusion, applying Melting solidification printing process...
The photothermal conversion efficiency of AuNPr–PEG after albumin corona formation and the effect irradiation on protein structure were evaluated.
Here we report the incorporation of gold nanostructures (nanospheres or nanorods, functionalized with carboxylate-end PEG) and curcumin oil-in-water (O/W) nanoemulsions (CurNem) into alginate microgels using dripping technique. While are promising nanomaterials for photothermal therapy applications, CurNem possess important pharmacological activities as reported here. In this sense, evaluated effect on cell viability both cancerous non-cancerous lines (AGS HEK293T, respectively),...
Gold nanoparticles (AuNPs) have been shown to be outstanding tools for drug delivery and biomedical applications, mainly owing their colloidal stability, surface chemistry, photothermal properties. The biocompatibility stability of can improved by capping the with endogenous proteins, such as albumin. Notably, protein coating interfere decrease cell penetration. Therefore, in present study, we functionalized albumin r8 peptide (All-D, octaarginine) used it NIR-plasmonic anisotropic gold...
This work aimed to synthesize and characterize a nanocarrier that consisted of ternary system, namely β-cyclodextrin-based nanosponge (NS) inclusion compounds (ICs) associated with silver nanoparticles (AgNPs) increase the antimicrobial activity quercetin (QRC). The nanosystem was developed overcome therapeutical limitations QRC. host-guest interaction between NSs QRC confirmed by field emission scanning electron microscopy (FE-SEM), X-ray powder diffraction (XRPD), thermogravimetric...
Gold nanostars (AuNSs) have achieved special relevance for potential biomedical applications, e.g., in theranostics. In relation to this, some authors explored controlling the conditions that trigger structural and morphological changes these structures. this work, we studied can of AuNSs or maintain their stability, such as ligand exchange nonthiolated thiolated species. First, synthesis stabilizing AuNS, 4-(2-hydroxyethyl)-1-piperazinapropanesulfonic acid (EPPS), was exchanged species...
<title>Abstract</title> Background Cutaneous melanoma is an aggressive type of cancer characterized by rapid progression, resistance to chemotherapy, and metastasis the lung. Conventional chemotherapy andradiotherapy are principal approaches for treating metastasizing tumors, but lack targeting results in severe side effects low treatment efficacy. Nanoparticles reportedly increase selectivity, given that they can accumulate at specific locations owing enhanced permeation retention (EPR)...
Introduction: The development of new materials and tools for radiology is key to the implementation this diagnostic technique in clinics. In work, we evaluated differential accumulation peptide-functionalized GNRs a transgenic animal model (APPswe/PSENd1E9) Alzheimer’s disease (AD) by computed tomography (CT) measured pharmacokinetic parameters bioaccumulation nanosystem. Methods: were functionalized with two peptides, Ang2 D1, which conferred on them properties crossing blood-brain barrier...
Gold nanospheres (GNS) and cyclodextrins (CD) have been extensively researched for their promising roles in drug delivery. GNS can be effectively functionalized with a range of molecules, serving as versatile carriers biomedical applications. Meanwhile, CD may form inclusion complexes diverse drugs, increasing permeability through cellular membranes. On the other hand, intranasal administration is non-invasive route delivery that has shown potential targeting central nervous system (CNS),...
<p>La propiedad electroactiva de hidroquinona (HQ) se estudió sobre un electrodo carbono vítreo modificado con quitosano, nanotubos pared múltiple<br />(Ch-MWCNT-GCE). La HQ depositó a potencial controlado la superficie del y oxidación midió por voltametría onda cuadrada (SWV, sus siglas en inglés). Se observó una corriente a<br />0,39 V reducción 0,21 ΔV 0,18 V; ello indicó proceso reversible. Un aumento las corrientes casi 50% cuando el Ch-MWCNT-GCE recubrió líquido...
@LatinXChem is a virtual forum through which the community of Latin American chemists, located anywhere in world, can share and discuss their research results advances. More than 1200 posters from 43 countries were received its first version, with 20 million impacts on Twitter. The second event organized by will be #LXChem2021 Conference (September 20, 2021), where divided into eleven categories discussed via
Un sensible y simple método electroanalítico es optimizado para la determinación de amaranth por AdSV sobre un electrodo serigrafiado carbono (Dropsens DRP-154). El (E123) depositado adsorción superficie del el pico corriente medido onda cuadrada (SWV). se caracterizó voltamperometría cíclica (CV) en presencia surfactante catiónico bromuro cetilpiridina (CPB) donde E123 oxidado a 0,62 V proceso controlado difusión, aumentando 100% CPB. Las variables experimentales como pH, concentración (C...
Se estudió la interacción del Rojo de Pirogalol (RP) sobre superficie un electrodo decarbono vítreo modificado con película oro (AuF) y cisteamina (cis). Teniendo presente elorden modificación, se encontró que respuesta oxidación RP presentó mayorcorriente el electro-depositadasobre carbono (GC/AuF/Cis/E), cual permite a potencialde 0,48 V pH 3,25. Con método univariable buscó parámetros óptimos, tales comopH, velocidad barrido (Ʋ), potencial adsorción (Eads) tiempo (tads),obteniéndose...