Steven Kapeles

ORCID: 0000-0001-5470-671X
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About
Contact & Profiles
Research Areas
  • Pregnancy and Medication Impact
  • Ubiquitin and proteasome pathways
  • Cardiac, Anesthesia and Surgical Outcomes
  • Organ Donation and Transplantation
  • Renal and Vascular Pathologies
  • Renal Transplantation Outcomes and Treatments
  • Anesthesia and Sedative Agents
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Infective Endocarditis Diagnosis and Management
  • Protein Degradation and Inhibitors
  • Thyroid and Parathyroid Surgery
  • Cardiac Structural Anomalies and Repair
  • Parathyroid Disorders and Treatments
  • Reproductive System and Pregnancy
  • Cardiac Valve Diseases and Treatments
  • Prenatal Screening and Diagnostics
  • Surgical Simulation and Training
  • CAR-T cell therapy research
  • Maternal and fetal healthcare
  • Risk and Safety Analysis
  • Assisted Reproductive Technology and Twin Pregnancy
  • Anesthesia and Neurotoxicity Research
  • Electronic Health Records Systems

Medical College of Wisconsin
2020-2022

University of Michigan–Ann Arbor
2013-2017

Ann Arbor Center for Independent Living
2014

Pregnancy after solid organ transplant is a significant priority for recipients but how patients report being counseled unknown.We performed single-center retrospective cohort study and telephone survey of female ages 18-49 at the time kidney, pancreas, or liver from 2000 to 2012 (n = 532). Data on pregnancy counseling, fertility, maternal, fetal- transplant-specific outcomes were collected. Multivariate Cox models assessed impact graft-specific outcomes.The response rate was 29% 152)....

10.1111/ctr.12393 article EN Clinical Transplantation 2014-06-17

BACKGROUND: Following the introduction of sugammadex to US clinical practice, scarce data are available understand its utilization patterns. This study aimed characterize patient, procedure, and provider factors associated with administration in patients. METHODS: retrospective observational was conducted across 24 Multicenter Perioperative Outcomes Group institutions United States on formulary at time study. All American Society Anesthesiologists (ASA) physical status I–IV adults undergoing...

10.1213/ane.0000000000005080 article EN Anesthesia & Analgesia 2020-07-21

BACKGROUND:Long-term outcomes of kidney transplantation recipients with bladder dysfunction or prior surgery are not well characterized. MATERIAL AND METHODS:Electronic records 1753 kidney-alone transplant between January 2000 and December 2008 were reviewed. We found that 1652 had normal function, 80 dysfunction, 21 substitute urinary diversion. Kaplan-Meier survival curves multivariable regression modeling performed to determine outcomes. RESULTS:Kaplan-Meier graft (p=.11) patient (p=.18)...

10.12659/aot.895975 article EN Annals of Transplantation 2016-04-19

You have accessJournal of UrologyTransplantation & Vascular Surgery II1 Apr 2014MP72-12 OUTCOMES OF KIDNEY TRANSPLANT RECIPIENTS WITH BLADDER DYSFUNCTION AND SUBSTITUTION Dushyanth Srinivasan, John Stoffel, Steven Kapeles, Kori Bradley, and Randell Sung SrinivasanDushyanth Srinivasan More articles by this author , StoffelJohn Stoffel KapelesSteven Kapeles BradleyKori Bradley SungRandell View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.2251AboutPDF ToolsAdd to...

10.1016/j.juro.2014.02.2251 article EN The Journal of Urology 2014-03-28

Abstract Post-translational modifications (PTMs) of proteins modulate cellular processes. However, the role, specifically that neddylation (a type PTM), in regulating immune cells is not known. Neddylation Cullin-RING ligase (CRL) protein modulates process ubiquitination. Thus, CRL activity critical for quotidian functions cells. We explored role dendritic (DCs) utilizing small molecule inhibitor (MLN4924) and knockdown SAG, a adapter element CRL. Inhibition DC significantly reduced...

10.4049/jimmunol.190.supp.63.39 article EN The Journal of Immunology 2013-05-01
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