A5043441484- Minimally Invasive Surgical Techniques
- Lipoproteins and Cardiovascular Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Renal cell carcinoma treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bladder and Urothelial Cancer Treatments
- Cardiac Imaging and Diagnostics
- Diabetes Management and Research
- Diabetes Treatment and Management
- Pediatric Urology and Nephrology Studies
- Venous Thromboembolism Diagnosis and Management
- Urinary and Genital Oncology Studies
- COVID-19 Clinical Research Studies
- Renal and Vascular Pathologies
- Anesthesia and Pain Management
- Atherosclerosis and Cardiovascular Diseases
- Distributed and Parallel Computing Systems
- Cancer, Lipids, and Metabolism
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Health and Disease Prevention
- Hernia repair and management
- Blood Pressure and Hypertension Studies
- Hormonal Regulation and Hypertension
West China Hospital of Sichuan University
2016-2025
Sichuan University
2016-2025
Tibet University
2025
Tianjin University
2025
Southern University of Science and Technology
2024
University of Birmingham
2024
Tianjin Medical University General Hospital
2019-2024
Chevron Phillips Chemical (United States)
2022-2024
Chengdu University of Traditional Chinese Medicine
2024
Tengzhou Central People's Hospital
2014-2024
Processed herbs have been widely used in eastern and western medicine; however, the mechanism of their medicinal effects has not yet revealed. It is commonly believed that a central role played by chemically active molecules produced herbs' metabolism. In this work, processed rhizoma polygonati (RP) other herbal foods are shown to exhibit intrinsic phosphatase-like (PL) activity bounded with formation nano-size flower-shaped assembly. Via quantum mechanical calculations, an enzymatic...
Purpose To evaluate the all-cause mortality rate and renal outcomes in patients with diabetes chronic kidney disease (CKD) following hospital discharge for COVID-19. Methods This single-center prospective observational study included 187 discharged COVID-19 CKD, admitted between December 2022 January 2023 at West China Hospital, Sichuan University. Cox regression analysis was used to assess risk, logistic applied identify risk factors rapid CKD progression after discharge. Results During...
Many factors could potentially affect the process of arsenic-induced liver fibrosis. The present study was undertaken to examine effect high fat diet on fibrosis and preneoplastic changes. Mice were given sodium arsenite (As3+, 200 ppm) or arsenate (As5+, in drinking water for 10 months, provided a normal containing 20% added fat. Serum aspartate aminotransferase (AST), indicative injury, elevated both groups, further increased these levels. Histopathology (H&E Masson stain) showed that...
Abstract Magnetic resonance imaging (MRI) is becoming the preferred neuroimaging modality for diagnosis of human amyotrophic lateral sclerosis (ALS). A useful animal model ALS superoxide dismutase 1 G93A G1H transgenic mouse, which shows many clinico‐pathological features condition. We have employed a 4.7‐Tesla MRI instrument to determine whether noninvasive approach can reveal pathological changes in nervous system this model. Our T 2 ‐weighted revealed consistent brain and brainstem these...
Glycemic variability (GV) still remains unclear whether acute glycemic excursion has the important prognostic significance in ST-segment elevation myocardial infarction (STEMI) patients undergoing p-PCI. So our aim is to assess value of GV STEMI We studied 237 p-PCI, whose clinical and laboratory data were collected. used a continuous glucose monitoring system (CGMS) measure fluctuations blood glucose. Participants grouped into diabetes group non-diabetes group, tertiles mean amplitude...
Water-soluble fluorescent carbon dots (C-dots) were synthesized through hydrothermal process using date pits pre-treated with phosphoric acid as a source. Transmission electron microscopy showed that the C-dots have an average particle size of 1.1 ± 0.3 nm very narrow distribution. The aqueous solution or phosphate buffer (PBS) prepared exhibits strong fluorescence when excited at 338 nm. PBS can inhibit growth by much 61% well migration human lung cancer (A549), breast (MCF-7) and prostate...
Both hyperuricemia and hypertension have important clinical implications, but their relationship in terms of gender age is still a matter debate. In this study, we aimed to explore gender- age-specific differences association between Chinese population. A total 78596 ostensibly healthy subjects (47781 men 30815 women) were recruited. The was analyzed by multivariate logistic regression, the analyses stratified age. Overall prevalence significantly higher males than females. Increasing trends...
Emerging evidence has linked cholesterol metabolism with platelet responsiveness. We sought to examine the dose-response relationship between low-density lipoprotein (LDL-C) and major in-hospital bleeds in acute coronary syndrome (ACS) patients.Among 42 378 ACS patients treated percutaneous intervention (PCI) enrolled 240 hospitals Improving Care for Cardiovascular Disease China-ACS project from 2014 2019, a total of 615 bleeds, 218 ischaemic events, 337 deaths were recorded. After...
The association between prolactin and mortality has been less studied, findings were inconsistent among different populations. We aimed to investigate the serum (PRL) patients with type 2 diabetes.We performed a retrospective cohort study of 10 907 at least measurements within years since their first inpatient diagnosis diabetes. Baseline mean values PRL used as exposures. A multivariable-adjusted Cox proportional hazards model was estimate mortality. During follow-up 5.34 years, 863 died,...
Previous studies suggest that the complexity of glucose time series may serve as a novel marker homeostasis.We aimed to investigate relationship between and all-cause mortality in patients with type 2 diabetes.Prospective data 6000 adult inpatients diabetes from single center were analyzed. The index (CGI) based on continuous monitoring (CGM) was measured at baseline refined composite multiscale entropy. Participants stratified by CGI tertiles of: < 2.15, 2.15 2.99, ≥ 3.00. Cox proportional...
Background— Early invasive strategies and antithrombotic treatments are key of non–ST-segment–elevation acute coronary syndrome (NSTE-ACS). Few studies have examined the use these in patients with NSTE-ACS China. This study aimed to assess applications compare their outcomes. Methods Results— A nationwide registry study, Improving CCC (Care for Cardiovascular Disease China) ACS project, was launched 2014 as a collaborative American Heart Association Chinese Society Cardiology (CSC), 142...
Zr metallocenes have significant potential to be highly tunable polyethylene catalysts through modification of the aromatic ligand framework. Here we report development multiple machine learning models using a large library (>700 systems) DFT-calculated zirconocene properties and barriers for ethylene polymerization. We show that very accurate are possible HOMO–LUMO gaps precatalysts but performance significantly depends on algorithm type featurization, such as fingerprints, Coulomb...