Martin A. Nowak

ORCID: 0000-0001-5489-0908
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About
Contact & Profiles
Research Areas
  • Evolutionary Game Theory and Cooperation
  • Evolution and Genetic Dynamics
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Experimental Behavioral Economics Studies
  • HIV Research and Treatment
  • Cancer Genomics and Diagnostics
  • Game Theory and Applications
  • Plant and animal studies
  • Immune Cell Function and Interaction
  • Evolutionary Psychology and Human Behavior
  • HIV/AIDS Research and Interventions
  • Mathematical Biology Tumor Growth
  • Microtubule and mitosis dynamics
  • Language and cultural evolution
  • T-cell and B-cell Immunology
  • COVID-19 epidemiological studies
  • Opinion Dynamics and Social Influence
  • Evolutionary Algorithms and Applications
  • Origins and Evolution of Life
  • CRISPR and Genetic Engineering
  • HIV/AIDS drug development and treatment
  • Pancreatic and Hepatic Oncology Research
  • RNA and protein synthesis mechanisms
  • Genetic factors in colorectal cancer
  • Complex Network Analysis Techniques

Harvard University Press
2014-2025

Harvard University
2015-2024

Manhattan College
2018-2022

Evolutionary Genomics (United States)
2011-2020

Passport Systems (United States)
2020

The University of Texas System
2017

National Institute of Public Health
2015

University of Bremen
2014

Johannes Gutenberg University Mainz
2008-2014

University of Göttingen
2013

Although highly active antiretroviral therapy (HAART) in the form of triple combinations drugs including protease inhibitors can reduce plasma viral load some HIV-1-infected individuals to undetectable levels, it is unclear what effects these regimens are on latently infected CD4+ T cells and role play persistence HIV-1 infection receiving such treatment. The present study demonstrates that purified from 13 patients HAART with an average treatment time 10 months (<500 copies HIV RNA/ml)...

10.1073/pnas.94.24.13193 article EN Proceedings of the National Academy of Sciences 1997-11-25

Preface 1. Introduction 2. What Evolution Is 3. Fitness Landscapes and Sequence Spaces 4. Evolutionary Games 5. Prisoners of the Dilemma 6. Finite Populations 7. in 8. Graph Theory 9. Spatial 10. HIV Infection 11. The Virulence 12. Dynamics Cancer 13. Language 14. Conclusion Further Reading References Index

10.5860/choice.44-4439 article EN Choice Reviews Online 2007-04-01

Although cytotoxic T lymphocytes (CTLs) are thought to be involved in the control of human immunodeficiency virus–type 1 (HIV-1) infection, it has not been possible demonstrate a direct relation between CTL activity and plasma RNA viral load. Human leukocyte antigen–peptide tetrameric complexes offer specific means directly quantitate circulating CTLs ex vivo. With use complexes, significant inverse correlation was observed HIV-specific frequency In contrast, no association detected...

10.1126/science.279.5359.2103 article EN Science 1998-03-27

Mathematical models, which are based on a firm understanding of biological interactions, can provide nonintuitive insights into the dynamics host responses to infectious agents and suggest new avenues for experimentation. Here, simple mathematical approach is developed explore relation between antiviral immune responses, virus load, diversity. The model results compared data cytotoxic T cell viral diversity in infections with human leukemia (HTLV-1) immunodeficiency (HIV-1).

10.1126/science.272.5258.74 article EN Science 1996-04-05
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