A5101565271- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Parkinson's Disease Mechanisms and Treatments
- Nerve injury and regeneration
- Memory and Neural Mechanisms
- Pain Mechanisms and Treatments
- Photoreceptor and optogenetics research
- Neurogenesis and neuroplasticity mechanisms
- Neuropeptides and Animal Physiology
- Cardiovascular and Diving-Related Complications
- Anesthesia and Neurotoxicity Research
- Neuroendocrine regulation and behavior
- Advanced Neuroimaging Techniques and Applications
- Estrogen and related hormone effects
- Chemical Synthesis and Analysis
- Mitochondrial Function and Pathology
- Birth, Development, and Health
- Gout, Hyperuricemia, Uric Acid
- High Altitude and Hypoxia
- Pharmacological Effects of Natural Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Restraint-Related Deaths
- Neuroscience and Neural Engineering
- Prenatal Substance Exposure Effects
- Epilepsy research and treatment
Chengdu University of Traditional Chinese Medicine
2006-2025
Sichuan University
2024
Xi'an Jiaotong University
2004-2021
Ministry of Education of the People's Republic of China
2021
Baylor College of Medicine
1995
Coronary air embolism is a rare but severe complication of coronary interventions.
Abstract Monoamine oxidase B (MAO B) inhibitors, which inhibit dopamine decomposition by antagonizing MAO activity, are approved and widely used for clinical treatment of Parkinson's disease (PD). Nonetheless, the mechanism abnormally increased activity in PD is still unclear. Previous research showed transcription factor specificity protein 1 (SP1) directly regulates binding SP1 sequence promoter. In our study, we first observed that level promoter were 1‐methyl‐4‐phenylpyridinium (MPP + )...
<b><i>Background:</i></b> Depression is one of the most common neuropsychiatric disturbances in Parkinson’s disease (PD), but its pathophysiology not definite. Lines evidence have indicated that hippocampus and serotonin 1A (5-HT<sub>1A</sub>) receptors are related to regulation depression. <b><i>Objective:</i></b><i></i>The purpose present study was observe effect 5-HT<sub>1A</sub> dorsal (dHIP) on...
The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while mechanisms remain to be clarified.The effects possible mecha-nism underlying activation or blockade 5-HT4 receptors (5-HT4Rs) LHb depression were investigated by behavioral neurochemical methods based on a Parkinson's disease (PD) rat model.6-Hydroxydopamine (6-OHDA) was injected unilaterally into substantia nigra pars compacta establish PD model....
Objectives: This study aimed to investigate the effect of serotonin6 (5-HT6) receptors in dorsal hippocampus (dHip) on regulation Parkinson's disease (PD)-associated anxiety. Methods: We examined whether intra-dHip injection both 5-HT6 receptor agonist and antagonist was involved anxiety-like behaviors sham-operated rats with unilateral 6-hydroxydopamine (6-OHDA) lesions medial forebrain bundle by open-field elevated plus maze (EPM) tests. Four weeks after 6-OHDA, concentrations dopamine...
Objective: The aim of the present study was to investigate effects and mechanism 6-hydroxydopamine (6-OHDA) lesions serotonin 4 (5-HT4) receptors in lateral habenula (LHb) on Parkinson's disease (PD) related working memory. Methods: memory measured by T-maze rewarded alternation test sham rats with unilateral 6-OHDA substantia nigra pars compacta (SNc). concentrations dopamine (DA), noradrenaline (NA) 5-HT brain regions were neurochemistry.Results: results showed that SNc induced impairment....
To study the roles of protein synthesis inhibitors in long-term potentiation(LTP) and depotentiation(DP) hippocampal CA1 region adult rats.Standard extracellular recording technique was used to record field EPSP(fEPSP) evoked by Schaffer collateral stimulation from subfield rat slices. Paired-pulse low-frequency stimulation(PP-LFS) or high-intensity paired-pulse stimulation(HI-PP-LFS) delivered induce depotentiation 2 h after LTP induction induced six theta-burst stimulations. Protein were...