- Clostridium difficile and Clostridium perfringens research
- Microscopic Colitis
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Infection Control in Healthcare
- Viral gastroenteritis research and epidemiology
- Helicobacter pylori-related gastroenterology studies
- Infection Control and Ventilation
- Pneumocystis jirovecii pneumonia detection and treatment
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Gene Regulatory Network Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Bacterial Identification and Susceptibility Testing
- Medical Device Sterilization and Disinfection
- Cerebrospinal fluid and hydrocephalus
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Respiratory viral infections research
- Antibiotic Resistance in Bacteria
- Cardiac, Anesthesia and Surgical Outcomes
- Influenza Virus Research Studies
- Gastroesophageal reflux and treatments
- Cardiac Arrest and Resuscitation
Cleveland Clinic
2016-2025
University of Illinois Chicago
2025
International Institute of Information Technology
2025
International Institute of Information Technology, Hyderabad
2023-2024
Cleveland Clinic Lerner College of Medicine
2011-2024
Case Western Reserve University
2013-2024
New York Proton Center
2015-2024
Communities In Schools of Orange County
2022-2024
University of Pittsburgh
2024
Lindsay Unified School District
2022-2024
Importance Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common cause of chronic and projected to become leading indication for transplant (LT) in US. Understanding its clinical burden can help identify opportunities prevention treatment. Objective To project MASLD US adults from 2020 2050. Design, Setting, Participants This decision analytical modeling study used an agent-based state transition model that simulates natural history progression among 18 years...
Objective. Effective disinfection of hospital rooms after discharge patients with Clostridium difficile infection (CDI) is necessary to prevent transmission. We evaluated the impact sequential cleaning and interventions by culturing high-touch surfaces in CDI cleaning. Design. Prospective intervention. Setting. A Veterans Affairs hospital. Interventions. During a 21-month period, 3 tiered were implemented: (1) fluorescent markers provide monitoring feedback on thoroughness facility-wide, (2)...
Single-center studies suggest an increasing incidence of acute pancreatitis (AP) in children. Our specific aims were to (i) estimate the recent secular trends, (ii) assess disease burden, and (iii) define demographics comorbid conditions AP hospitalized children within United States.We used Healthcare Cost Utilization Project Kids' Inpatient Database, Agency for Research Quality years 2000 2009. Extracted data weighted generate national-level estimates. We Cochrane-Armitage test analyze...
Importance Recurrent Clostridioides difficile infection (CDI) is a debilitating disease leading to poor health-related quality of life (HRQOL), loss productivity, anxiety, and depression. The potential association treatment with HRQOL has not been well evaluated. Objectives To explore the SER-109 compared placebo on in patients recurrent CDI up week 8. Design, Setting, Participants This study was secondary analysis randomized, double-blind, placebo-controlled trial that took place at 56...
Diarrhea is a frequent and potentially severe complication in solid organ transplant (SOT) recipients. One of the most common infectious etiologies diarrhea these patients Clostridium difficile. Our objective was to investigate association C. difficile infection (CDI) with outcomes hospitalized SOT patients.We extracted all adult cases discharge diagnoses or CDI from United States Nationwide Inpatient Sample, Healthcare Cost Utilization Project, Agency for Research Quality 2009 database. We...
Background The intestinal microbiota protect the host against enteric pathogens through a defense mechanism termed colonization resistance. Antibiotics excreted into tract may disrupt resistance and alter normal metabolic functions of microbiota. We used mouse model to test hypothesis that alterations in levels bacterial metabolites fecal specimens could provide useful biomarkers indicating disrupted or intact after antibiotic treatment. Methods To assess vivo resistance, mice were...