A5026288878- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Nutritional Studies and Diet
- Health disparities and outcomes
- Smoking Behavior and Cessation
- Colorectal Cancer Screening and Detection
- Breast Cancer Treatment Studies
- Air Quality and Health Impacts
- Vitamin D Research Studies
- Estrogen and related hormone effects
- Phytoestrogen effects and research
- Physical Activity and Health
- Cardiovascular Health and Risk Factors
- Carcinogens and Genotoxicity Assessment
- Nutrition, Genetics, and Disease
- Glutathione Transferases and Polymorphisms
- Effects and risks of endocrine disrupting chemicals
- BRCA gene mutations in cancer
- Radiation Effects and Dosimetry
- Global Public Health Policies and Epidemiology
- Skin Protection and Aging
- Health, Environment, Cognitive Aging
- Cancer Genomics and Diagnostics
- Phytase and its Applications
- Cancer survivorship and care
Stanford University
2010-2024
Cancer Prevention Institute of California
2010-2020
Stanford Cancer Institute
2020
University of California, Berkeley
2014
University of Southern California
2012-2014
University of California, Los Angeles
2014
University of California, San Francisco
2014
Berkeley Public Health Division
2014
Fred Hutch Cancer Center
2011
Northern California Research
1999-2010
Abstract Substantial experimental evidence indicates that the hormonal form of vitamin D promotes differentiation and inhibits proliferation, invasiveness, metastasis human prostatic cancer cells. Results from epidemiologic studies status and/or receptor (VDR) polymorphisms prostate risk have been mixed. We conducted a population-based, case-control study advanced among men ages 40 to 79 years San Francisco Bay area. Interview data on lifetime sun exposure other factors were collected for...
Abstract Background: Migrant studies have shown that breast cancer risk increases in women who move from countries with low incidence rates to high rates. We examined the influence of migration history and acculturation on Hispanic ages 35 79 years. Methods: In a population-based case-control study conducted San Francisco Bay Area, information history, language usage, other factors for was collected through an in-person interview 991 cases 1,285 controls. Results: Breast 50% lower...
Research is limited on the independent and joint effects of individual- neighborhood-level socioeconomic status (SES) breast cancer survival across different racial/ethnic groups.
Considerable evidence indicates that vitamin D may reduce the risk of several cancers, including breast cancer. This study examined associations cancer with sun exposure, principal source D, and receptor gene (VDR) polymorphisms (FokI, TaqI, BglI) in a population-based case-control Hispanic, African-American, non-Hispanic White women aged 35–79 years from San Francisco Bay Area California (1995–2003). In-person interviews were obtained for 1,788 newly diagnosed cases 2,129 controls. Skin...
Mounting experimental and epidemiologic evidence supports the hypothesis that vitamin D reduces risk of prostate cancer. Some suggests cancer may be influenced by sun exposure early in life. We analyzed data from National Health Nutrition Examination Survey I Epidemiologic Follow-up Study to examine associations with early-life adult residential exposures were assessed through self-report, physician report, dermatologic examination. used solar radiation state birth as a measure 1971 1975...
Consumption of red meat, particularly well-done has been associated with increased prostate cancer risk. High-temperature cooking methods such as grilling and barbecuing may produce heterocyclic amines (HCAs) polycyclic aromatic hydrocarbons (PAHs), which are known carcinogens. We assessed the association meat consumption estimated HCA PAH exposure in a population-based case-control study cancer. Newly diagnosed cases aged 40–79 years (531 advanced cases, 195 localized cases) 527 controls...
Few risk factors have been identified for triple negative breast cancer (TNBC) which lacks expression of estrogen receptor (ER), progesterone (PR) and human epidermal growth factor 2 (HER2). This more aggressive subtype disproportionately affects some racial/ethnic minorities is associated with lower survival. We pooled data from three population-based studies (558 TNBC 5,111 controls) examined associations reproductive history breast-feeding. estimated odds ratios (ORs) 95% confidence...
Red meat, processed and unprocessed, has been considered a potential prostate cancer (PCA) risk factor; epidemiological evidence, however, is inconclusive. An association between meat intake PCA may be due to potent chemical carcinogens that are generated when meats cooked at high temperatures. We investigated the red poultry localized advanced taking into account cooking practices polymorphisms in enzymes metabolize accumulate meats. analyzed data for 1096 controls, 717 1140 cases from...
Abstract Background Associations between reproductive factors and risk of breast cancer differ by subtype defined joint estrogen receptor (ER), progesterone (PR), HER2 expression status. Racial ethnic differences in the incidence subtypes suggest etiologic heterogeneity, yet data are limited because most studies have included non-Hispanic White women only. Methods We analyzed harmonized for 2,794 cases 4,579 controls, whom 90% self-identified as African American, Asian American or Hispanic....
Large body size has been associated with a reduced risk of premenopausal breast cancer in non-Hispanic white women. Data on other racial/ethnic populations are limited. The authors examined the association between and adult 672 cases 808 controls aged ≥35 years from population-based case-control study conducted 1995–2004 San Francisco Bay Area (Hispanics: 375 cases, 483 controls; African Americans: 154 160 whites: 143 165 controls). Multivariate adjusted odds ratios 95% confidence intervals...
Abstract High dietary fiber intake has been associated with reduced breast cancer risk, but few studies considered tumor subtypes defined by estrogen receptor ( ER ) and progesterone PR status or included racial/ethnic minority populations who vary in their intake. We analyzed food frequency data from a population‐based case–control study, including 2135 cases (1070 Hispanics, 493 African Americans, 572 non‐Hispanic Whites NHW s)) 2571 controls (1391 557 623 s). Odds ratios OR 95% confidence...
Abstract Background: The role of moderate physical activity and life patterns in reducing endometrial cancer risk remains uncertain. Methods: We assessed lifetime histories from recreation, transportation, chores, occupation other factors a population-based case-control study conducted the San Francisco Bay area. analysis was based on 472 newly diagnosed cases ascertained by regional registry 443 controls identified random-digit dialing who completed an in-person interview. Results: Reduced...
Cooking fish at high temperature can produce potent carcinogens such as heterocyclic amines and polycyclic aromatic hydrocarbons. The effects of these may undergo modification by the enzymes responsible for their detoxification and/or activation. In this study, we investigated genetic polymorphisms in nine carcinogen metabolism modifying on association between white or dark consumption prostate cancer (PCA) risk. We genotyped 497 localized 936 advanced PCA cases 760 controls from California...
Little is known about neighborhood attributes that may influence opportunities for healthy eating and physical activity in relation to breast cancer mortality. We used data from the California Breast Cancer Survivorship Consortium Neighborhoods Data System (CNDS) examine environment, body mass index, mortality after cancer. studied 8,995 African American, Asian Latina, non-Latina white women with Residential addresses were linked CNDS characterize neighborhoods. multinomial logistic...