Hongjun Li

ORCID: 0000-0001-5553-6062
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About
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Research Areas
  • HIV Research and Treatment
  • Liver Disease Diagnosis and Treatment
  • HIV-related health complications and treatments
  • Infectious Diseases and Tuberculosis
  • COVID-19 Pandemic Impacts
  • Bone fractures and treatments
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Hematological disorders and diagnostics
  • Hepatitis C virus research
  • Diagnosis and treatment of tuberculosis
  • Liver Disease and Transplantation
  • HIV/AIDS drug development and treatment
  • Peripheral Neuropathies and Disorders
  • Liver physiology and pathology
  • Photoacoustic and Ultrasonic Imaging
  • Hepatitis B Virus Studies
  • COVID-19 epidemiological studies
  • Respiratory viral infections research
  • Myasthenia Gravis and Thymoma
  • Liver Diseases and Immunity
  • Fetal and Pediatric Neurological Disorders
  • Cerebrovascular and Carotid Artery Diseases
  • Viral Infections and Vectors
  • Pelvic and Acetabular Injuries
  • Adrenal and Paraganglionic Tumors

Tsinghua University
2021-2025

Capital Medical University
2013-2023

Beijing YouAn Hospital
2013-2023

Tianjin Medical University
2023

Second Hospital of Tianjin Medical University
2023

Weatherford College
2022

Beihang University
2022

Capital University
2018

Wuhan Sixth Hospital
2012

Background Metagenomic next-generation sequencing (mNGS) is a promising technology that allows unbiased pathogen detection and increasingly being used for clinical diagnoses. However, its application in urinary tract infection (UTI) still scarce. Methods The medical records of 33 patients with suspected UTI who were admitted to the Second Hospital Tianjin Medical University from March 2021 July 2022 received urine mNGS retrospectively analyzed. performance conventional culture diagnosing...

10.3389/fcimb.2023.1119020 article EN cc-by Frontiers in Cellular and Infection Microbiology 2023-03-03

<title>Abstract</title> Following the end of zero-COVID policy, China’s economic recovery elicited high hopes but turned out to be disappointing in 2023. This paper provides a novel explanation for slow based on city network disruption and restructuring after major shocks. The supply-demand connections, once disrupted by lockdowns, could not revert their pre-lockdown state reopening. Instead, they underwent further restructuring, incurring considerable transaction costs. Using unique dataset...

10.21203/rs.3.rs-4702066/v1 preprint EN cc-by Research Square (Research Square) 2025-01-20

Cryptococcus neoformans is the most common opportunistic CNS fungal pathogen in HIV-positive patients. About 7%–8% of patients will have cryptococcal meningoencephalitis. Imaging plays an important role evaluation infection brain. Abnormal findings correlated with higher risk death. The paper review pathogenesis, pathology, imaging characterization and complication combined

10.1016/j.jrid.2016.05.003 article EN Radiology of Infectious Diseases 2016-06-11

Endovascular surgery is advantageous in experimentally induced ischemic stroke because it causes fewer cranial traumatic lesions than invasive and can closely mimic the pathophysiology patients. However, outcomes are highly variable, which limits accuracy of evaluations studies. In this study, eight healthy adult rhesus monkeys were randomized into two groups with four each group: middle cerebral artery occlusion at origin segment (M1) M2 segment. The blood flow was blocked completely for 2...

10.4103/1673-5374.147936 article EN cc-by-nc-sa Neural Regeneration Research 2014-01-01

Objective: The brain relies on the glymphatic system to clear metabolic wastes and maintain homeostasis fulfill its functions better. Yet, complexity of flow clearance changes in HIV infection role neurocognitive dysfunction remain poorly understood. This study aims explore impact combination antiretroviral therapy (cART) establish a potential biomarker HIV-associated disorders (HAND). Methods Here, we examined profiles middle-aged virosuppressed patients with ( n = 27) receiving cART over...

10.3389/fneur.2022.819594 article EN cc-by Frontiers in Neurology 2022-03-11

Hepatic fibrosis (HF), as the only reversible process of chronic liver disease, remains a big diagnostic challenge. Development noninvasive and effective methods to assess quantitatively early-stage HF is great clinical importance. Compared with conventional methods, near-infrared fluorescence imaging (NIR) magnetic resonance (MRI) could offer highly sensitive spatial resolution signals for detection. However, precise detection using contrast agents not possible. Superparamagnetic iron oxide...

10.1039/c7ra10847h article EN cc-by RSC Advances 2018-01-01

Inactivated SARS-CoV-2 vaccines have been deployed in a significant portion of the world population, who widely varied responses to vaccination. Understanding this differential response would help development new for non-responders. Here, we conducted surveillance anti-Spike receptor-binding domain (RBD) antibody levels large cohort 534 healthy Chinese subjects vaccinated with two doses inactivated vaccines. We show that positive rate antibodies among rapidly wanes as interval between...

10.1128/spectrum.02783-22 article EN cc-by Microbiology Spectrum 2023-03-14

In patients with hepatitis B-related cirrhosis, it is important to predict those at high-risk of oesophagogastric variceal haemorrhage (OVH) decide upon prophylactic treatment. Our published model developed right liver lobe volume and diameters portal vein system did not incorporate maximum size as a factor. This study thus aimed develop an improved based on volume, varices (OV) obtained magnetic resonance imaging (MRI) OVH.Two hundred thirty consecutive individuals cirrhosis undergoing...

10.21037/qims-23-353 article EN Quantitative Imaging in Medicine and Surgery 2023-11-24

In China, there are 789617 patients infected by HIV/AIDS until March 2018. DTI is sensitive to the integrity of tissue microstructure. The changes in SIV-mac239 rhesus monkey's structure and brain function very similar humans. This study designed relationship parameters(FA, AD) values peripheral blood examination results at time before infection, 12 weeks after infection 24 infection. Four healthy adult male monkeys(aged 3–5 years, weighted 5.0–7.0 kg) were involved. Linear regression...

10.1016/j.jrid.2019.01.001 article EN Radiology of Infectious Diseases 2019-01-09

Abstract Objective To investigate the variance of metablites, including N-Acetyl aspartate (NAA), Choline (Cho) and Creatine (Cr), in brain regions HIV infected patients with non-cognitive disorder healthy volunteers by a 3.0 T magnetic resonance spectroscopy. Methods Single voxel spectroscopy was applied to measure basal ganglia region, frontal lobe parietal 69 33 volunteers. According CD4 T cell count, were divided into 2 groups, group A (≥200 cells/μL, 40 patients) B ( Results The groups...

10.1016/j.jrid.2015.06.004 article EN Radiology of Infectious Diseases 2015-07-04

To study the radiological research tendency and indicate direction of virus hepatitis, a statistic analysis based on available literatures was carried out. The quantity literatures, secondary subjects, literature type, geographic distributions journal hepatitis image were all summarized. Such prompting would definitely facilitate to reveal findings corresponding theoretical connotation can be enriched fully developed guide clinical practice improve diagnostic level hepatitis.

10.1016/j.jrid.2015.10.001 article EN Radiology of Infectious Diseases 2015-09-01

To evaluate whether combinations of liver lobe and spleen volumes obtained on magnetic resonance imaging (MRI) could predict esophagogastric variceal bleeding (EVB) in hepatitis B-related cirrhotic patients. Ninety-six consecutive patients with cirrhosis underwent upper abdominal contrast-enhanced MRI within 1 week after initial hospitalization, grouped based outcomes EVB during the 2 years' follow-up being discharged. Total volume (TLV), (SV) 4 including right (RV), left medial (LMV),...

10.1097/md.0000000000030616 article EN cc-by-nc Medicine 2022-09-23

HIV infection targets at the human in body and targeting damage to immune system compromise result hypoimmunity. associated damages tissues organs as well AIDS related infections caused by various pathogens neoplasms are clinically common. diseases main cause of death patients with AIDS. Therefore, early prevention appropriate immediate treatment against play key role prolonging survival period improving quality life In recent years, medical radiology has gained rapid development, which...

10.1016/j.jrid.2015.05.003 article EN Radiology of Infectious Diseases 2015-06-01

Objective To evaluate the clinical efficacy of percutaneous piercing cortical bone at fracture ends and local injection autologous concentrated marrow aspirate (cBMA) platelet rich plasma (PRP) in treatment delayed union. Methods A retrospective study was performed on data 34 patients with union who had been treated Department Orthopaedics, Luoyang Zhenggu Hospital Henan Province from April 2014 to February 2017. They were 26 males 8 females, aged 18 63 years (average, 36.7 years)....

10.3760/cma.j.issn.1671-7600.2018.11.014 article EN Zhonghua chuangshang guke zazhi 2018-11-15
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