Chong Shen

ORCID: 0000-0002-7984-2846
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About
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Research Areas
  • COVID-19 epidemiological studies
  • Wind and Air Flow Studies
  • Building Energy and Comfort Optimization
  • Infection Control and Ventilation
  • Statistical Methods and Bayesian Inference
  • Viral Infections and Outbreaks Research
  • Probiotics and Fermented Foods
  • Bayesian Methods and Mixture Models
  • Retinal and Optic Conditions
  • Circular RNAs in diseases
  • Gut microbiota and health
  • MicroRNA in disease regulation
  • Urinary Tract Infections Management
  • Cancer-related molecular mechanisms research
  • Cancer Immunotherapy and Biomarkers
  • Bacterial Identification and Susceptibility Testing
  • Fungal Infections and Studies
  • Ophthalmology and Visual Health Research
  • Disaster Management and Resilience
  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • Vaccine Coverage and Hesitancy
  • Influenza Virus Research Studies
  • COVID-19 Pandemic Impacts
  • Zoonotic diseases and public health

He Eye Hospital
2024

Tsinghua University
2018-2023

Tianjin Medical University
2023

Second Hospital of Tianjin Medical University
2023

Hebei University of Engineering
2023

Technical University of Denmark
2018

Tongji University
2013

Background Metagenomic next-generation sequencing (mNGS) is a promising technology that allows unbiased pathogen detection and increasingly being used for clinical diagnoses. However, its application in urinary tract infection (UTI) still scarce. Methods The medical records of 33 patients with suspected UTI who were admitted to the Second Hospital Tianjin Medical University from March 2021 July 2022 received urine mNGS retrospectively analyzed. performance conventional culture diagnosing...

10.3389/fcimb.2023.1119020 article EN cc-by Frontiers in Cellular and Infection Microbiology 2023-03-03

Emerging evidence suggests a resurgence of COVID-19 in the coming years. It is thus critical to optimize emergency response planning from broad, integrated perspective. We developed mathematical model incorporating climate-driven variation community transmissions and movement-modulated spatial diffusions into various intervention scenarios. find that an intensive 8-wk targeting reduction local transmissibility international travel efficient effective. Practically, we suggest tiered...

10.1073/pnas.2012002117 article EN cc-by Proceedings of the National Academy of Sciences 2020-09-28

Candida albicans remains the most common species causing invasive candidiasis. In this study, we present population structure of 551 global C. strains. Of these, antifungal susceptibilities 370 strains were tested. Specifically, 66.6% azole-nonsusceptible (NS)/non-wild-type (NWT) that tested belonged to Clade 1. A phylogenetic analysis, a principal components structure, and loss heterozygosity events revealed two nested subclades in 1, namely, 1-R 1-R-α, exhibited higher azole-NS/NWT rates...

10.1128/spectrum.03807-22 article EN cc-by Microbiology Spectrum 2023-01-26

PurposeTo assess the impact of COVID-19 pandemic on a worldwide private ophthalmic practice.DesignIn this retrospective study, we reviewed 2020 monthly outpatient and surgical volume refractive, cataract, retinal disease in Aier Eye clinics/hospitals different regions, including United States, Germany, Spain, Italy, six major cities China (Wuhan, Beijing, Shanghai, Shenyang, Urumqi Yili). All these data were compared to those same period 2019.ResultsOverall, during early stage (2020 January...

10.1016/j.heliyon.2024.e25841 article EN cc-by-nc-nd Heliyon 2024-02-01

Mobility restrictions have been a heated topic during the global pandemic of coronavirus disease 2019 (COVID-19). However, multiple recent findings verified its importance in blocking virus spread. Evidence on association between mobility, cases imported from abroad and local medical resource supplies is limited. To reveal association, this study quantified inter- intra-country mobility containing spread avoiding hospitalizations early stages COVID-19 outbreaks India, Japan, China. We...

10.3390/ijerph18062826 article EN International Journal of Environmental Research and Public Health 2021-03-10

Abstract Modeling the global dynamics of emerging infectious diseases (EIDs) like COVID-19 can provide important guidance in preparation and mitigation pandemic threats. While age-structured transmission models are widely used to simulate evolution EIDs, most these studies focus on analysis specific countries fail characterize spatial spread EIDs across world. Here, we developed a simulator that integrates disease 3,157 cities explored its usage under several scenarios. We found without...

10.1093/pnasnexus/pgad127 article EN cc-by PNAS Nexus 2023-04-25

Clear cell renal carcinoma (ccRCC) is identified as a malignant tumor in the urinary tract. The research was an attempt to probe biological function and molecular mechanism of lncRNA LINC00667 ccRCC development.qRT-PCR monitored LINC00667, miR-143-3p, ZEB1 levels. models overexpression or knockdown were constructed cells. Cell proliferation, apoptosis, migration, invasion cells detected. levels apoptosis-associated proteins epithelial-mesenchymal transition (EMT)-related proteins, detected...

10.18632/aging.205029 article EN cc-by Aging 2023-10-11

Aim: Missing data appeared in dementia's cross-sectional studies. Non-responders were related to diagnosis and would lead biased estimation of prevalence if not properly handled. We aimed introduce a robust approach estimate the under framework propensity score stratification, which could significantly reduce negative impact non-responders on estimation.Methods: The probability each participant Chinese Veteran Clinical Research being non-responder (i.e., score) was estimated via logistic...

10.2139/ssrn.4173049 article EN SSRN Electronic Journal 2022-01-01
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