A5101545466- Bariatric Surgery and Outcomes
- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Obesity and Health Practices
- Esophageal Cancer Research and Treatment
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Diverticular Disease and Complications
- Colorectal Cancer Surgical Treatments
- Healthcare cost, quality, practices
- Dysphagia Assessment and Management
- Organ and Tissue Transplantation Research
- Body Contouring and Surgery
- SARS-CoV-2 detection and testing
- melanin and skin pigmentation
- Hematopoietic Stem Cell Transplantation
- Tuberous Sclerosis Complex Research
- Diet and metabolism studies
- dental development and anomalies
- CNS Lymphoma Diagnosis and Treatment
- Hernia repair and management
- Eicosanoids and Hypertension Pharmacology
- Anorectal Disease Treatments and Outcomes
- Cardiovascular Disease and Adiposity
- Prenatal Screening and Diagnostics
Singapore General Hospital
2008-2025
SingHealth Duke-NUS Academic Medical Centre
2023
Nanyang Technological University
2023
Sengkang General Hospital
2021-2023
Lincoln Electric (United States)
2021
University of Minnesota Medical Center
2017
Universiti Teknologi MARA
2013
Hospital Universiti Sains Malaysia
2013
St. Vincent's University Hospital
2011
Yonsei University Health System
2009
Bariatric surgery is the most effective treatment for morbid obesity and reduces severity of nonalcoholic fatty liver disease (NAFLD) in long term. Less known about effects bariatric on fat, inflammation, fibrosis during early stages following surgery.This exploratory study utilises advanced imaging methods to investigate NAFLD changes metabolic transitional period surgery.Nine participants with underwent sleeve gastrectomy. Multiparametric MRI (mpMRI) magnetic resonance elastography (MRE)...
Objective. Bariatric surgery effectively treats non-alcoholic fatty liver disease (NAFLD). The glutamate-serine-glycine (GSG) index has emerged as a non-invasive diagnostic marker for NAFLD, but its ability to monitor treatment response remains unclear. This study investigates the GSG index's NAFLD's bariatric surgery. Methodology. Ten NAFLD participants were studied at baseline and 6 months post-bariatric Blood samples collected serum biomarkers metabolomic profiling. Hepatic steatosis...
Bleeding from renal angiomyolipoma in pregnancy can be catastrophic to both mother and fetus. Selective arterial embolisation is considered more superior than conventional surgery these patients. Our case report exemplifies how a bleeding was halted with our pregnant patient.
Hertwig’s epithelial root sheath (HERS) cells play a pivotal role during formation of the tooth and are able to form cementum-like tissue. The aim present study was establish HERS cell line for molecular biochemical studies using selective digestion method. Selective performed by application trypsin-EDTA 2 min, which led detachment fibroblast-like-cells, with rounded attached culture plate. displayed typical cuboidal/squamous-shaped appearance. Characterization immunofluorescence staining...
Abstract The challenge arises among researchers when hair follicle stem cells (HFSCs) derived from a human remain poorly expanded in defined culture medium. In this study, we isolated the HFSCs and they became confluent after 10 days of cultivation. Comparing viability cultured keratinocytes serum free medium (KSFM) coated plate CnT07 an uncoated plate, number was significantly higher at 2, 4, 6 8 (P=0.004). population doubling time 21.48±0.44 hours non-coated plates with 30.73±0.75 KSFM....
Traditionally, catheter-based percutaneous cecostomy has been utilized in the setting of closed-looped colonic obstruction and selected patients with fecal incontinence whom conservative management failed. Although procedure is associated high rates technical success, complications including catheter migration or dislodgement are common occur up to a third patients. Catheter occlusion leakage from site also common, often occurring on skin (20 %) within peritoneum (12 [1] [2] [3] [4] [5]....
Introduction: Laparoscopic sleeve gastrectomy (LSG) is associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE). The role of crural repair during LSG still controversial. preoperative laxity the junction (GEJ), graded by Hill’s classification, more predictive for GERD EE after than presence a hiatal hernia seen on endoscopy. Thus, authors hypothesize that concomitant in specific subgroup patients lax GEJ (Hill’s III) may reduce incidence EE. Methods:...
<title>Abstract</title> <underline>Introduction</underline> The benefits of metabolic bariatric surgery (MBS) in people with body mass index (BMI) ≥50kg/m<sup>2</sup> are not well-established, concerns increased risk and poorer weight loss. Optimal surgical type (gastric bypass [GB] versus sleeve gastrectomy [SG]) is unclear, studies comparing complication rates, loss, glycemic outcomes reporting mixed results. <underline>Methods</underline> Participants BMI≥50kg/m<sup>2</sup> undergoing MBS...
Abstract Introduction Oesophageal leaks following minimal invasive oesophagectomy (MIE) present significant challenges to upper GI surgeons, with reported rates ranging from 11% 21%. Management strategies include: conservative, endoscopic, and surgical interventions. These vary based on patient clinical status institution. Here, we propose a hybrid approach involving thoracoscopic washout coupled antegrade T-tube insertion via gastroscopy for managing these complex leaks. Methods We describe...
Abstract Background: Laparoscopic sleeve gastrectomy (LSG) is one of the commonest bariatric procedures. However, it associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE). This study aims to assess impact various preoperative clinical endoscopic characteristics on development GERD EE. Methods: A single institution retrospective cohort involving all patients who underwent LSG. univariate multivariate analysis was performed identify parameters that...
Abstract Aim: Weight-based stigmatization is prevalent. They have been reported in schools, work and healthcare settings. However, almost all the literature on such weight-based stereotypes were from Western countries. The study aims to evaluate prevalence of an Asian population. Methods: An anonymized questionnaire-based cross-sectional was conducted. Respondents asked about their socioeconomic status, followed by questions perceived across 4 domains (self, social, healthcare, education). A...
Dear Editor,People with obesity contend obesity-related stigmas, in addition to health complications. 1 In contrast the West, literature documenting prevalence of such stigmas Asia is sparse.We report perceived weight-based stigmatisation Singapore.An anonymised questionnaire was administered 101 consecutive patients presenting a multidisciplinary weight management clinic single centre Singapore (Table 1).It based on by UK All-Party Parliamentary Group Obesity 2018. 2 The comprised...
Kee, T.; Joshi, V.; Erf, K. V.D.; Chow, W. L.; Swah, T. S.; Goh, P.; Tan, G.; Yeo, R.; Lim, C.; J.; Chan, C. M. Author Information
To determine the performance of screening for preeclampsia by combining second trimester maternal serum and uterine artery Doppler ultrasound. A total 876 women underwent both (using α-fetoprotein (AFP), uE3, human chorionic gonadotropin (hCG)), measurement uric acid, The sensitivity, specificity predictive value different combinations tests were compared. Of pregnancies originally participating, 38 (4.3%) developed preeclampsia. mean values hCG AFP significantly higher in with subsequent (P...
Abstract Background Postoperative outcomes vary considerably across bariatric patients and may be related to psychosocial factors. In this study, we examined whether a patient’s family support predicts weight loss the remission of type 2 diabetes (T2DM) up 5 years following surgery. Methods Between 2008 2018, 359 completed pre-surgical questionnaire before undergoing gastric bypass or sleeve gastrectomy. As part questionnaire, described their in terms structure (marital status, number...
Abstract This is a video submission of laparoscopic resection an epiphrenic oesophageal pulsion diverticulum secondary to achalasia. A Heller’s cardiomyotomy also performed together with Toupet fundoplication. Methods The patient 40 year old woman 12 month history worsening dysphagia, reflux symptoms, as well occasional regurgitation food, worse at night. Barium swallow showed distal and manometry confirmed type 1 Upper GI endoscopy no other intra-luminal findings. Results underwent the...