A5101873495- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Bioactive Compounds
- Ethnobotanical and Medicinal Plants Studies
- Plant biochemistry and biosynthesis
- Plant chemical constituents analysis
- Drug Solubulity and Delivery Systems
- Analytical Methods in Pharmaceuticals
- Synthesis and bioactivity of alkaloids
- Phytochemicals and Antioxidant Activities
- Pharmacological Effects of Natural Compounds
- Sesquiterpenes and Asteraceae Studies
- Phytochemical Studies and Bioactivities
- Microbial Metabolism and Applications
- Natural Antidiabetic Agents Studies
- Allelopathy and phytotoxic interactions
- Curcumin's Biomedical Applications
- Biological Activity of Diterpenoids and Biflavonoids
- Advancements in Transdermal Drug Delivery
- Phytochemistry and biological activity of medicinal plants
- Advanced Drug Delivery Systems
- Enzyme Production and Characterization
- Berberine and alkaloids research
- Phytochemicals and Medicinal Plants
Jazan University
2016-2025
University of Sfax
2025
Islamia University of Bahawalpur
2025
King Saud University
2013-2025
Maulana Azad National Urdu University
2024
University of Okara
2024
Guru Nanak Dev University
2022-2024
Bacha Khan University
2024
Jamia Hamdard
2011-2023
Mewar University
2023
Human PRL receptor cDNA clones from hepatoma (Hep G2) and breast cancer (T-47D) libraries were isolated by using a rat probe. The nucleotide sequence predicts mature protein of 598 amino acids with much longer cytoplasmic domain than the liver receptor. Although this extended region has additional segments localized identity human GH receptor, there is no any consensus sequences known to be involved in hormonal signal transduction. This will valuable tool better understand role development...
The screening of a size-selected cDNA library from the ovary revealed existence second form PRL receptor in rat. polypeptide sequence deduced cDNAs has much longer cytoplasmic domain (357 amino acids) than previously identified liver (57 acids). Nucleotide analysis and comparison with rabbit, mouse, human suggests that two forms rat result alternative splicing primary transcript. Complementary DNAs encoding long were also found prepared estradiol-treated liver, although they represent minor...
There are many different infections and factors that can lead to skin illnesses, but bacteria fungi the most frequent. The goal of this study was develop a hexatriacontane-loaded transethosome (HTC-TES) for treating conditions caused by microbes. HTC-TES developed utilizing rotary evaporator technique, Box-Behnken design (BBD) utilized improve it. responses chosen were particle size (nm) (Y1), polydispersity index (PDI) (Y2), entrapment efficiency (Y3), while independent variables lipoid...
The current perspective for the search of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitor has been shifted towards a natural agent also having antioxidant property. Thus, this study was intended to isolate and identify bioactive compounds from methanolic extract Ficus virens bark (FVBM) evaluate their antioxidant, HMG-CoA inhibitory hypolipidemic activity. Bioactivity guided fractionation isolation compound FVBM done characterize potent (HMGR) with activity by using...
A novel combination of antibiotic, ciprofloxacin (CIP) with herbal counterpart naringin (NAR) was encapsulated by an oleic acid lipid core and carboxymethyl chitosan (CM–CS)/Alginate (AG) nanoparticle composite (CIP + NAR–CM–CS/AG–NPs) for improved antimicrobial efficacy antibiotic. Herein, this study explored the design preparation a system that enables to deliver both CIP NAR from CM–CS/AG nanoparticles using nonsolvent ionic gelation technique. The (NPs) were fabricated long-acting...
The novel human coronavirus disease (COVID-19) is the major pandemic throughout globe and its occurrence due to presence of severe acute respiratory syndrome (SARS-CoV2). That began from Wuhan, Hubei province China in late 2019 afterward drastically spread worldwide. It effects around 213 countries territories have reported a total 8,128,490 confirmed cases COVID-19. As an unprecedented global it sweeps planet affects each every being either physically, mentally or economically. most common...
Carbofuran pesticide is used to control insects in agriculture and acts as a contaminant that pollutes aquatic ecosystems, exerting harmful effects on fish health. The present study was conducted evaluate the ameliorative of moringa leaf powder after being exposed carbofuran hematobiochemical histological changes, oxidative antioxidative mechanisms soft tissues rohu Labeo rohita. Fish were divided into three groups (A, B, C). Group A treated while B C two sublethal doses (0.32 0.84 mg/L) for...
The phytochemical investigation of the stem bark Tinospora cordifolia Miers (Menispermaceae) has afforded four new compounds, named tinosporafuranol, tinosporafurandiol, tinosporaclerodanol, and tinosporaclerodanoid, along with beta-sitosterol, their stereostructures have been elucidated correspondingly as 4-seco-cleroda-19-ol-13-furanoid, 4-seco-cleroda-6-en-18,19-diol-13-furanoid, cleroda-1(10)-en-6beta-ol cleroda-1-one-2-en-11beta,15,16,18-tetraol-12,19-olide on basis spectral data...
The chemical composition of the solvent extracted fixed oil black cumin (Nigella sativa L.) seeds was determined by capillary GC and GC/MS. Thirty-two fatty acids (99.9%) have been identified in oil. major were linoleic acid (50.2%), oleic (19.9%), margaric (10.3%), cis-11,14-eicosadienoic (7.7%) stearic (2.5%). effect on vitro percutaneous absorption model lipophilic drug carvedilol investigated using excised rat abdominal skin. Transdermal flux, permeability coefficient enhancement factor...
Carotenoids are essential pigments for human and plant life, but only plants can produce them.Seven hundred fifty carotenoids improve the lives of different organisms.The tomato is used as a model to get complete information on biosynthesis carotenoids.Different horticultural crops learn about biochemical genetic pathways.Some genes enzymes play significant role in regulating carotenoids, like SIPSY1 DXS.Similarly, some pathways, MEP pathway, contribute lot tomatoes.This study presents...
Berberine (BER) is an alkaloid obtained from berberis plant having broad biological activities including anticancer. BER-encapsulated alginate (ALG)/chitosan (CHS) nanoparticles (BER-ALG/CHS-NPs) were developed for long-acting improved treatment in breast cancer. The surface of the NPs was activated by a conjugation reaction, and thereafter, BER-ALG/CHS-NP grafted with folic acid (BER-ALG/CHS-NPs-F) specific targeting BER-ALG/CHS-NPs-F optimized applying Box-Behnken design using Expert...
Abstract: Many methods, including solid dispersion, micellization, and inclusion complexes, have been employed to increase the solubility of potent drugs. Beta-cyclodextrin (βCD) is a cyclic oligosaccharide consisting seven glucopyranoside molecules, widely used polymer for formulating soluble complexes hydrophobic The enzymatic activity Glycosyltransferase or α-amylase converts starch its derivatives into mixture cyclodextrins. βCD units are characterized by α-(1-4) glucopyranose bonds....
Pseudomonas aeruginosa is an opportunistic pathogen causing severe infection in animals and humans. This study aimed to determine the ecological distribution prevalence of multidrug-resistant (MDR) P. isolated from dairy cattle, environment, workers’ hand swabs. Samples (n = 440) were collected farms households 3, each). Rectal swabs, udder skin milk, feed, water, water sources, beddings collected. subjected bacterial identification via 16S rRNA. Antimicrobial resistance (AMR) was detected...
The environmental toxicology of heavy metals poses significant challenges due to their persistence, bioaccumulation, and severe health ecological impacts. Heavy such as lead, mercury, cadmium, arsenic enter the environment through industrial activities, mining, agricultural runoff, contaminating water, soil, air. Their removal is difficult they do not degrade naturally, traditional remediation methods, including chemical precipitation adsorption, often suffer from inefficiency, high costs,...