- Heterotopic Ossification and Related Conditions
- Viral Infections and Vectors
- Inflammasome and immune disorders
- Inflammatory Myopathies and Dermatomyositis
- Eosinophilic Disorders and Syndromes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Muscle and Compartmental Disorders
- Respiratory viral infections research
- Sarcoidosis and Beryllium Toxicity Research
University of Miami
2016-2019
Mount Sinai Hospital
2016
Interstitial lung disease (ILD) is a frequent complication of rheumatoid arthritis (RA), occurring in up to 40% patients during the course their disease. Early diagnosis critical, particularly given shared clinicoepidemiologic features between advanced arthritis-associated ILD (RA-ILD) and idiopathic pulmonary fibrosis (IPF). This study was undertaken define molecular basis this overlap through comparative profiling serum proteins RA-ILD IPF.Multiplex enzyme-linked immunosorbent assays...
Antisynthetase (AS) syndrome is a major subgroup of inflammatory myopathies seen in minority patients with dermatomyositis and polymyositis. Although it usually associated elevated creatine phosphokinase level, some may have amyopathic (ADM) like presentation predominant skin involvement. Interstitial lung disease (ILD) the main pulmonary manifestation be severe thereby determining prognosis. It rarely present very aggressive course resulting acute respiratory distress (ARDS). We report case...
Cryopyrin associated periodic syndrome (CAPS) is a dominantly-inherited autoinflammatory disease, which included in the group of fever syndromes. It caused by defect regulation inflammatory cytokines, particularly interleukin-1β. CAPS encompasses spectrum three phenotypes increasing severity: familial cold syndrome, Muckle-Wells (MWS) and neonatal onset multisystem disease. We report case 58-year-old male, who had migratory joint pains, daily urticaria, chills, episodic conjunctivitis since...