A5011319800- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Treatment of Major Depression
- Eating Disorders and Behaviors
- Virtual Reality Applications and Impacts
- Advanced Neuroimaging Techniques and Applications
- EEG and Brain-Computer Interfaces
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Neural and Behavioral Psychology Studies
- Electroconvulsive Therapy Studies
- Mental Health Treatment and Access
- Attention Deficit Hyperactivity Disorder
- Heart Rate Variability and Autonomic Control
- Cannabis and Cannabinoid Research
- Health Systems, Economic Evaluations, Quality of Life
- Tryptophan and brain disorders
- Neuroscience and Neural Engineering
- Visual perception and processing mechanisms
- Stress Responses and Cortisol
- Aesthetic Perception and Analysis
- Pain Management and Placebo Effect
- Visual Attention and Saliency Detection
- Sleep and Wakefulness Research
- Color perception and design
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2020-2025
Technische Universität Ilmenau
2023
University of Southern California
2023
University of Milan
2015-2023
Ospedale Maggiore
2021-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2022
University of Milano-Bicocca
2017
Vita-Salute San Raffaele University
2014
Abstract Background Despite well-established guidelines for managing major depressive disorder, its extensive disability burden persists. This Value of Treatment mission from the European Brain Council aimed to elucidate nature and extent “gaps” between best-practice current-practice care, specifically to: 1. Identify current treatment gaps along care pathway determine these in comparison with stepped-care model 2. Recommend policies intending better meet patient needs (i.e., minimize gaps)....
Background It is still unclear which biological changes are needed to recover from a major depressive episode. Current perspectives focus on cortical synaptic neuroplasticity. Measures of responses evoked by transcranial magnetic stimulation (TMS) change with sleep homeostasic pressure in humans and approximate measures strength animal models. Using repeated total deprivation as model antidepressant treatment, we aimed correlate recovery depression these excitability. Methods We recorded...
Introduction Awe is a complex emotion unveiling positive and mixed nature, which resembles the Romantic feeling of Sublime. It has increasingly become object scientific investigation in last twenty years. However, its underlying brain mechanisms are still unclear. To fully capture nature lab, researchers have relied on virtual reality (VR) as an emotion-elicitation method, can resemble even phenomena limited space. In this work, multidisciplinary team proposed novel experimental protocol...
Abstract Introduction Awe is a complex emotion unveiling positive and mixed nature, which resembles the Romantic feeling of Sublime. It has increasingly become object scientific investigation in last twenty years. However, its underlying brain mechanisms are still unclear. To fully capture nature lab, researchers have relied on virtual reality (VR) as an emotion-elicitation method, can resemble even phenomena limited space. In this work, multidisciplinary team proposed novel experimental...
Neuromodulation of regions involved in food processing is increasingly used studies on eating behaviors, but results are controversial. We assessed the effects anodal transcranial direct current stimulation (a-tDCS) and body implicit preferences patients with disorders (EDs).Thirty-six ED 36 healthy females completed three sessions a-tDCS applied to medial-prefrontal cortex (mPFC), right extrastriate area (rEBA) or sham mode. Each participant then Implicit Association Tests (IATs)...
Background: Depressive episodes, especially when resistant to pharmacotherapy, are a hard challenge face for clinicians and leading cause of disability worldwide. Neuromodulation has emerged as potential therapeutic option treatment-resistant depression (TRD), in particular transcranial magnetic stimulation (TMS). In this article, we present case series six patients who received TMS with an accelerated intermittent theta-burst (iTBS) protocol public healthcare setting. Methods: We enrolled...
Abstract Background Major depressive disorder (MDD) is highly prevalent across Europe. While evidence-based treatments exist, many people with MDD have their condition undetected and/or untreated. This study aimed to assess the cost-effectiveness of reducing treatment gaps using a modeling approach. Methods A decision-tree model covering 27-month time horizon was used. followed care pathway where could be detected or not, and different forms provided. Expected costs pertaining Germany,...
Introduction: Binge eating disorder (BED) is the most common disorder, affecting a large population worldwide. It characterized by recurrent episodes of binge eating, with no compensatory behaviors. BED often associated psychiatric comorbidities, and still represents challenge in terms treatment strategies. In last years, neuromodulation has represented promising approach BED. We report cases two women, affected Bipolar Disorder Type II (BD-II) comorbid BED, whose symptoms improved after...
Although the interaction between brain and heart, through autonomic nervous system, is an established phenomenon, multimodal studies that have explored their bidirectional interplay are still limited. In this context, objective of present study was to investigate coupling sympathetic vagal dynamics functional connectivity during resting state, thanks simultaneously acquired electrocardiogram magnetic resonance imaging (fMRI) data. Twenty healthy controls (67.42 ± 10.81 years, 60% females)...
This scientific research represents a novel investigation into the neural underpinnings of complex awe emotion, made possible with an innovative experimental setup that integrates nature-based Virtual Reality scenarios (nVRs) concurrent recording electroencephalography (EEG) signals. The noninvasive EEG technique enables to capture brain electrical activity in real time and therefore holds great promise elucidating dynamics associated emotional experiences. A group 15 healthy volunteers...
Cannabis is the illicit drug most commonly used worldwide, and its consumption can both induce psychiatric symptoms in otherwise healthy subjects unmask a florid psychotic picture patients with prior risk. Previous studies suggest that chronic long-term cannabis exposure may exert significant negative effects brain areas enriched cannabinoid receptors. However, whether alterations determined by dependency will lead to clinically phenotype or outbreak at some point of an abuser's life remains...
Cannabis is the illicit drug most commonly used worldwide, and its consumption can both induce psychiatric symptoms in otherwise healthy subjects unmask a florid psychotic picture patients with prior risk. Previous studies suggest that chronic long-term cannabis exposure may exert significant negative effects brain areas enriched cannabinoid receptors. However, whether alterations determined by dependency will lead to clinically phenotype or outbreak at some point of an abuser's life remains...