A5016526464- Pregnancy and Medication Impact
- COVID-19 Impact on Reproduction
- Pharmacovigilance and Adverse Drug Reactions
- Maternal Mental Health During Pregnancy and Postpartum
- Pharmaceutical industry and healthcare
- Pharmaceutical studies and practices
- Reproductive Health and Contraception
- Drug-Induced Adverse Reactions
- Academic integrity and plagiarism
- Clinical practice guidelines implementation
- Pharmaceutical Economics and Policy
- Vasculitis and related conditions
- Pregnancy and preeclampsia studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Vaccine Coverage and Hesitancy
- Attachment and Relationship Dynamics
- Venomous Animal Envenomation and Studies
- Acne and Rosacea Treatments and Effects
- Psoriasis: Treatment and Pathogenesis
- Chronic Disease Management Strategies
- Inflammatory Bowel Disease
- Sleep and Work-Related Fatigue
- Anesthesia and Sedative Agents
- Nail Diseases and Treatments
- Prenatal Screening and Diagnostics
Netherlands Pharmacovigilance Centre Lareb
2011-2023
University of Otago
2003
Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities study design and methodology. This aimed examine patterns factors associated with medications from a multinational perspective, emphasis type of utilised indication for use.Cross-sectional, web-based performed within the period 1 October 2011 29 February 2012. Uniform collection drug utilisation data was via an anonymous online questionnaire.Multinational Europe (Western, Northern...
Evidence on perinatal mental health during the coronavirus disease 2019 (COVID-19) pandemic and its potential determinants is limited. Therefore, this multinational study aimed to assess status of pregnant breastfeeding women pandemic, explore associations between depressive symptoms, anxiety, stress women's sociodemographic, health, reproductive characteristics.A cross-sectional, web-based was performed in Ireland, Norway, Switzerland, Netherlands, UK 16 June 14 July 2020. Pregnant up 3...
The COVID-19 pandemic may be of particular concern for pregnant and breastfeeding women. We aimed to explore their beliefs about the coronavirus vaccine willingness assess impact on perinatal experiences practices. A multinational, cross-sectional, web-based study was performed in six European countries between April July 2020. anonymous survey promoted via social media. In total, 16,063 women participated (including 6661 9402 women). Most responses were collected from Belgium (44%), Norway...
To describe the mental health of perinatal women in five European countries during third pandemic wave and identify risk factors related to depressive anxiety symptoms.A cross-sectional, online survey-based study.Belgium, Norway, Switzerland, Netherlands UK, 10 June 2021-22 August 2021.Pregnant up 3 months postpartum women, older than 18 years age.The Edinburgh Depression Scale (EDS) Generalised Anxiety Disorder scale (GAD-7) were used assess status. Univariate multivariate generalised...
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • More and more countries accept patient reporting in their spontaneous systems. Media exposure about drugs can influence patients health professionals. Evaluation of adverse drug reactions is needed to provide further evidence its benefits. STUDY ADDS Patient compared with by professionals after media attention statins. reports additional insight into impact on daily life, the patient–health professional relationship general worries next...
The aim of this study was to quantify the reasons and opinions patients who reported adverse drug reactions (ADRs) in Netherlands a pharmacovigilance centre.A web-based questionnaire sent 1370 had previously an ADR centre. data were analysed using descriptive statistics, χ(2) tests Spearman's correlation coefficients.The response rate 76.5% after one reminder. main for report ADRs share their experiences (89% agreed or strongly agreed), severity reaction (86% statement), worries about own...
Background No previous studies have explored how closely women follow their psychotropic drug regimens during pregnancy. This study aimed to explore patterns of and factors associated with low adherence medication Methods Multinational web-based was performed in 18 countries Europe, North America, Australia. Uniform data collection ensured via an electronic questionnaire. Pregnant were eligible participate. Adherence measured the 8-item Morisky Medication Scale (MMAS-8). The Beliefs about...
Insight into the epidemiology of perinatal medication use during COVID-19 pandemic is scarce. Therefore, a cross-sectional study using an anonymous web survey was performed in Ireland, Norway, Switzerland, The Netherlands, and United Kingdom (UK) to investigate prevalence type medications used by pregnant breast-feeding women first wave. Factors associated with were estimated logistic regression. In total, 8378 participated (i.e., 3666 4712 breastfeeding women). Most responses collected...
Introduction Implementation of breastfeeding recommendations is hampered by–among others–lacking information regarding medicine safety during breastfeeding. This article describes the clinical and pharmacokinetic data mothers using clopidogrel (CLP) as secondary prevention following (suspicion of) a cerebrovascular accident. Methods A 29-year-old 42-year-old woman were chronically treated with 75 mg CLP once daily. Human milk samples collected at 7 9 months (patient 1), 14 postpartum 2)....
Aims Metformin is used to treat type 2 diabetes, polycystic ovary syndrome associated infertility, and gestational diabetes. This study aims evaluate the safety of metformin in early pregnancy. Method We evaluated risk major birth defects pregnancy losses a cohort pregnant women exposed during first trimester for different indications relative matched unexposed reference group. Results The was 5.1% (20/392) pregnancies 2.1% (9/431) group [adjusted odds ratio (OR) 1.70; 95% CI 0.70–4.38]....
Information on medication utilization among pregnant and postpartum women during the pandemic is lacking. We described prevalence patterns of self-reported use third wave (June–August 2021). An online questionnaire was distributed in five European countries between June–August 2021. Pregnant or who had delivered three preceding months, ≥18 years old, could participate. The overall use, self-medication, changes chronic were determined. A total 2158 out 5210 participants (41.4%) used at least...
Objective To assess whether there is an association between statin use and the occurrence of polymyalgia rheumatic (PMR) in spontaneous reporting database World Health Organisation (WHO). Methods We conducted a case/non-case study based on individual case safety reports (ICSR) WHO global ICSR (VigiBase). Case containing adverse event term rheumatica (WHOART or MedDRA Preferred Term) were defined as cases. Non-cases all other terms. Each was matched to five non-cases by age, gender, time...
<h3>Objectives</h3> Envenoming resulting from snake bites is a serious public health problem in many regions of the world. The aim this study to describe difficulties management envenomation prefecture San Mali. <h3>Methods</h3> A retrospective cases, recorded Health Reference Center (Ségou region) 2001–2003, was conducted. <h3>Results</h3> During period study, 88 victims were received and treated at San. Of these, 42% farmers 6,8% shepherds. Adults 15 years over most commonly concerned...
Selective serotonin reuptake inhibitors (SSRIs) have been reported to inhibit uptake into platelets, resulting in decreased platelet function. We report a case of large intraventricular haemorrhage 6‐h‐old boy, whose mother used paroxetine during pregnancy.
With COVID-19 vaccination hesitancy at around 50% in the obstetric population, it is critical to identify which women should be addressed and how. Our study aimed assess willingness among pregnant postpartum Europe investigate associated determinants. This was a cross-sectional, web-based survey conducted Belgium, Norway, Switzerland, The Netherlands, United Kingdom (UK) June–August 2021. Among 3194 women, proportions of vaccinated or willing ranged from 80.5% Belgium 21.5% Norway....
Objective.—To demonstrate that sumatriptan may induce activation or aggravation of pain at sites inflammation caused by trauma disease. Methods.—Case reports from the national pharmacovigilance centers 2 countries, The Netherlands and New Zealand, are presented. These come programs use methodologies to monitor drugs for adverse reactions: spontaneous reporting a prospective observational cohort study. potential mechanisms production discussed in detail. Results.—Thirteen case following...
The objective of this study was to describe pregnancy- and birth-related experiences postpartum women during the third wave COVID-19 pandemic their association with mental health outcomes. An online questionnaire distributed in five European countries (Belgium, Netherlands, Norway, Switzerland, UK) between June August 2021. Participants were recruited though social media platforms including motherhood-related websites, pregnancy fora, apps. Postpartum asked eleven specific questions about...