A5016131707- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Neonatal and Maternal Infections
- Estrogen and related hormone effects
- Hormonal and reproductive studies
- Birth, Development, and Health
- Neonatal and fetal brain pathology
- Maternal Mental Health During Pregnancy and Postpartum
- Neonatal Health and Biochemistry
- Pregnancy and Medication Impact
- Reproductive Health and Contraception
- Infant Nutrition and Health
- Neuroscience of respiration and sleep
- Pregnancy and preeclampsia studies
- Breastfeeding Practices and Influences
- Ovarian function and disorders
- Sexual Differentiation and Disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Streptococcal Infections and Treatments
- Reproductive System and Pregnancy
- Preterm Birth and Chorioamnionitis
- Pediatric Urology and Nephrology Studies
- Parvovirus B19 Infection Studies
- Prenatal Substance Exposure Effects
Schneider Children's Medical Center
2016-2025
Tel Aviv University
2016-2025
Rabin Medical Center
2009-2023
Maccabi Health Care Services
2018
Azienda Ospedaliero-Universitaria Careggi
2015
Columbia University Irving Medical Center
2009
Biotherapy of Genetic Diseases, Inflammatory Disorders and Cancers
2009
New York University
2009
Friedrich Schiller University Jena
2009
Fairfax Neonatal Associates
2006
To compare the prevalence and clinical characteristics of neonatal abstinence syndrome in neonates exposed not to selective serotonin reuptake inhibitors (SSRIs) utero.Cohort study.Tertiary care center. Patients One hundred twenty term infants, whom 60 had prolonged utero exposure SSRIs, including paroxetine hydrochloride, fluoxetine, citalopram hydrobromide, sertraline venlafaxine hydrochloride.Neonatal was assessed with Finnegan score as follows: 8 or above, severe; 4 7, mild; 0 3, normal....
Objective. High-grade intraventricular hemorrhage (IVH) is an important cause of severe cognitive and motor neurologic impairment in very low birth weight infants associated with a high mortality rate. The risk IVH inversely related to gestational age weight. Previous studies have proposed number factors for IVH; however, lack adequate matching may confounded the results. purpose this study was identify variables that affect high-grade IVH, using retrospective case-control clinical study....
BACKGROUND: Early-onset sepsis (EOS) is associated with significant morbidity and mortality among infants a very low birth weight (VLBW); however, there sparse amount of complete data on large cohorts. OBJECTIVE: To evaluate the major morbidities VLBW EOS. METHODS: This was population-based observational study. Data were prospectively collected by Israel Neonatal Network all born in from 1995 through 2005. Univariate multivariable analyses performed to assess independent association EOS...
Episodes of hyperoxaemia and hypocapnia, which may contribute to brain injury, occur unintentionally in severely asphyxiated neonates the first postnatal hours.To determine whether and/or hypocapnia during 2 hours life add risk injury after intrapartum asphyxia.Retrospective cohort study term infants with post-asphyxial hypoxic ischaemic encephalopathy (HIE) born between 1985 1995. Severe moderate were defined as Pao(2) >26.6 >13.3 kPa (200 100 mm Hg). Paco(2) <2.6 <3.3 (20 25 Adverse...
To estimate the effect of gestational age on short-term neonatal morbidity in cases spontaneous, low-risk singleton late preterm deliveries and to identify predictors adverse outcome.This was a retrospective study all (34 0/7 36 6/7 weeks gestation) during years 1997 2006 (n=2,478). Multiple gestations pregnancies complicated by premature rupture membranes (PROM) or maternal fetal complications were excluded. Short-term outcome compared with control group full-term 3:1 ratio (n=7,434)....
To build predictive models of severe adverse outcome at various times in the course neonatal bacterial meningitis.Retrospective cohort study with follow-up to a minimum age 1 year term and near-term infants, admitted between 1979 1998 regional tertiary care center. Predictors detectable (death or moderate neurosensory impairment) were identified by univariate analysis. Independent predictors multivariate Predictive tree constructed 12, 24, 48, 96 hours after admission discharge.Of 101...
The objective of this study is to determine the true incidence early neonatal hypoglycemia and confirm potential risk factors.The was conducted at tertiary Medical Center in Israel, between June September 2014. First blood glucose concentrations all infants admitted nursery were measured using a "point care" analyzer (Accu-Chek). We recorded factors for such as birth weight, gestational age, maternal diabetes demographics analyzed their association with two cutoffs: 40 47 mg/dl.Of 4000...
Selective serotonin reuptake inhibitors (SSRIs) have been suspected of cardiac teratogenicity, but reports inconsistent. Our aim was to investigate the rate nonsyndromic congenital heart defects in newborns exposed utero SSRIs compared with unexposed controls.This prospective study women who gave birth at our tertiary center from 2000 2007 yielded 235 reported first-trimester SSRI use during pregnancy. All born period and found a persistent murmur on day 2 or 3 life were referred for...
<h3>Objective</h3> To assess the association of anthropometric measurements with neonatal complications in macrosomic newborns non-diabetic mothers. <h3>Design</h3> Retrospective cohort study. <h3>Patients</h3> All liveborn, singleton, full term birth weight ≥4000 g born to mothers at a tertiary medical centre 1995–2005 (n=2766, study group) were matched next born, healthy, infant 3000–4000 (control group). Exclusion criteria multiple birth, congenital infection, major malformations and...
To determine the independent association of post-term pregnancy with neonatal outcome in low-risk newborns.Retrospective cohort.Tertiary university-affiliated medical centre.All newborns singleton pregnancies born at 39+0 to 44+0 weeks' gestation over a 5-year period.multiple gestation, maternal hypertensive disorder, diabetes or cholestasis, placental abruption intrapartum fever (>38°C), small for gestational age (<10th centile) and major congenital chromosomal anomalies.None.Admission...
Objective Size at birth is a key indicator of in utero growth. Our objective was to generate sex-specific percentiles for weight and head circumference neonates born between 22 29 weeks gestation from pregnancies without hypertension or diabetes assess differences vaginal caesarean births singletons twins. Methods We used data 12 countries participating the International Network Evaluating Outcomes Neonates database 2007 2021. excluded that were influenced by truncation with 1500g cut-offs...
This study evaluated the outcome of infants exposed to tranexamic acid during lactation.A prospective, controlled observational design was used. Mothers who contacted Beilinson Teratology Information Service (BELTIS) regarding use while breastfeeding were followed up by phone interview. Data on lactation, neonatal symptoms, and outcomes at age 1-3 years obtained. Mothers' taking their compared with those a matched control group mothers using drug known be safe lactation (amoxicillin)...
Aims Metformin is used to treat type 2 diabetes, polycystic ovary syndrome associated infertility, and gestational diabetes. This study aims evaluate the safety of metformin in early pregnancy. Method We evaluated risk major birth defects pregnancy losses a cohort pregnant women exposed during first trimester for different indications relative matched unexposed reference group. Results The was 5.1% (20/392) pregnancies 2.1% (9/431) group [adjusted odds ratio (OR) 1.70; 95% CI 0.70–4.38]....
<h3>Importance</h3> Feeding intolerance is a common condition among preterm infants owing to immaturity of the gastrointestinal tract. Enteral insulin appears promote intestinal maturation. The concentration in human milk declines rapidly post partum and absent formula; therefore, recombinant (rh) for enteral administration as supplement formula may reduce feeding infants. <h3>Objective</h3> To assess efficacy safety 2 different dosages rh both formula. <h3>Design, Setting, Participants</h3>...
Late-onset sepsis is associated with significant morbidity and mortality among very low birth weight (VLBW) infants. Our objective was to determine risk factors late-onset present temporal trends in overall pathogen-specific rates.Population-based study by the Israel Neonatal Network on VLBW infants (≤1500 g) born between 1995 2019. required clinical symptoms microbiologic confirmation. Bivariate multivariable analyses were performed identify factors. The period divided into 4 epochs....
This multicenter, observational prospective cohort study addresses the risk associated with exposure to mirtazapine during pregnancy. Pregnancy outcomes after were compared 2 matched control groups: (1) any selective serotonin reuptake inhibitor (SSRI, subjects a psychiatric condition) and (2) no medication known be teratogenic or antidepressant (general subjects). Data collected by members of European Network Teratology Information Services between 1995 2011. Observations from 357 exposed...