A5053261792- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Congenital Heart Disease Studies
- Child and Adolescent Health
- Congenital Diaphragmatic Hernia Studies
- Retinopathy of Prematurity Studies
- Neuroscience of respiration and sleep
- Ear Surgery and Otitis Media
- Assisted Reproductive Technology and Twin Pregnancy
- Emergency and Acute Care Studies
- Preterm Birth and Chorioamnionitis
- Global Maternal and Child Health
- Congenital heart defects research
- Tracheal and airway disorders
- Infant Nutrition and Health
- Maternal and Perinatal Health Interventions
- Birth, Development, and Health
- Cardiovascular Conditions and Treatments
- Cancer-related Molecular Pathways
- Infant Health and Development
- Mechanical Circulatory Support Devices
- Sinusitis and nasal conditions
- Hedgehog Signaling Pathway Studies
- Respiratory Support and Mechanisms
Turku University Hospital
2015-2025
University of Turku
2015-2025
Universidad de Salamanca
2021
Research Network (United States)
2020
Imperial College London
2019-2020
Academic Pediatric Association
2020
Royal Hospital for Women
2018
University of Toronto
2018
University of Otago
2018
University of Zurich
2018
OBJECTIVES: To compare survival rates and age at death among very preterm infants in 10 national regional neonatal networks. METHODS: A cohort study of infants, born between 24 29 weeks’ gestation weighing <1500 g, admitted to participating units 2007 2013 the International Network for Evaluating Outcomes Neonates. Survival was compared by using standardized ratios (SRs) comparing each network estimate whole population. RESULTS: populations differed with respect cesarean birth,...
Abstract Objective To determine if postnatal transfer or birth in a non-tertiary hospital is associated with adverse outcomes. Design Observational cohort study propensity score matching. Setting National health service neonatal care England; population data held the Neonatal Research Database. Participants Extremely preterm infants born at less than 28 gestational weeks between 2008 and 2015 (n=17 577) grouped based on within 48 hours of birth: upward (non-tertiary to tertiary hospital,...
<b><i>Background:</i></b> There are significant international variations in chronic lung disease rates among very preterm infants yet there is little data on respiratory strategies. <b><i>Objective:</i></b> To evaluate practice the management of extremely born at &#x3c; 29 weeks’ gestational age (GA) 10 neonatal networks participating International Network for Evaluating Outcomes (iNeo) Neonates collaboration....
<h3>Objective</h3> To compare the rates of retinopathy prematurity (ROP) and treatment ROP by laser or intravitreal anti-vascular endothelial growth factor among preterm neonates from high-income countries participating in International Network for Evaluating Outcomes (iNeo) neonates. <h3>Methods</h3> A retrospective cohort study was conducted on extremely infants weighing <1500 g at 24<sup>0</sup> to 27<sup>6</sup> weeks9 gestation who were admitted neonatal units Australia/New Zealand,...
Organisation of care, perinatal and neonatal management very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim this observational study was test hypothesis.Information on 21 greater healthcare Denmark, Finland, Iceland, Norway Sweden gathered from national registers 2021. Preterm birth rates, case-mix, interventions, morbidity survival hospital discharge (<32 weeks) extremely (<28 weeks gestational age) compared.Out 287 642 born alive, 16 567 (5.8%)...
<b><i>Introduction:</i></b> This study aimed to evaluate how Close Collaboration with Parents (CC), a neonatal intensive care unit (NICU)-wide educational model for healthcare staff improve their family-centred practices, affects the length of stay (LOS), growth, and later hospital visits rehospitalizations preterm infants. <b><i>Methods:</i></b> register-based included all infants born below 35 weeks gestation in Finland from 2006 2020....
Objective Size at birth is a key indicator of in utero growth. Our objective was to generate sex-specific percentiles for weight and head circumference neonates born between 22 29 weeks gestation from pregnancies without hypertension or diabetes assess differences vaginal caesarean births singletons twins. Methods We used data 12 countries participating the International Network Evaluating Outcomes Neonates database 2007 2021. excluded that were influenced by truncation with 1500g cut-offs...
Our objective was to evaluate the temporal trend of systemic postnatal steroid (PNS) receipt in infants 24-28 weeks' gestational age, identify characteristics associated with PNS receipt, and correlate incidence bronchopulmonary dysplasia (BPD) BPD/death from an international cohort included iNeo network.We conducted a retrospective study using data 2010 2018 seven networks participating (Canada, Finland, Israel, Japan, Spain, Sweden, Switzerland). Neonates 24 28 age who survived 7 days...
Background: Tympanometry can indicate middle ear effusion in children referred for tympanostomy tube placement. In outpatient setting, objective adjunctive tools are needed to diagnose the otitis media spectrum. Methods: We enrolled and followed 515 aged 6–35 months at primary care level. compared tympanometry with pneumatic otoscopy evaluated proportions of type A, C1, C2, Cs B tympanograms relation specific otoscopic diagnoses 2206 1006 examinations symptomatic asymptomatic visits,...
<b><i>Background:</i></b> Rates of retinopathy prematurity (ROP) and ROP treatment vary between neonatal intensive care units (NICUs). Neonatal practices, including oxygen saturation (SpO<sub>2</sub>) targets criteria for the screening ROP, are potential contributing factors to variations. <b><i>Objectives:</i></b><i></i> To survey variations in SpO<sub>2</sub> 2015 (and whether there had been recent changes)...
Studies concerning spectral gradient acoustic reflectometry (SG-AR) have analyzed middle ear effusion only as 1 entity. The usefulness of SG-AR to detect specific otoscopic diagnoses otitis media in young children is unknown.Among 515 aged 6-35 months, we compared with pneumatic otoscopy and evaluated the proportions 5 manufacturer-recommended levels relation 2802 1240 examinations at symptomatic asymptomatic visits, respectively.At when angle value was >95° (level 1), healthy diagnosed 76%...
Objectives To compare necrotising enterocolitis (NEC) prevention practices and NEC associated factors between units from eight countries of the International Network for Evaluation Outcomes Neonates, to assess their association with surgical rates. Design Prospective unit-level survey combined retrospective cohort study. Setting Neonatal intensive care in Australia/New Zealand, Canada, Finland, Israel, Spain, Sweden, Switzerland Tuscany (Italy). Patients Extremely preterm infants born 24 0...
To compare the neonatal outcomes of very preterm triplets with those matched singletons using a large international cohort.A retrospective matched-cohort study and born between 2007 2013 in International Network for Evaluation Outcomes neonates database countries by gestational age, sex, country birth was conducted. The primary outcome composite mortality or severe morbidity (severe neurologic injury, treated retinopathy prematurity, bronchopulmonary dysplasia). Unadjusted adjusted odds...
Pathogenic variants in the transcription factor TP63 gene cause a variety of clinical phenotypes, such as ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome and ankyloblepharon-ectodermal (AEC) syndrome. Historically, TP63-related phenotypes have been divided into several syndromes based on both presentation location pathogenic variant gene. This division is complicated by significant overlap between syndromes. Here we describe patient with characteristics different TP63-associated...
<b><i>Introduction:</i></b> The availability of and variability in healthcare professionals neonatal units different countries has not been well characterized. Our objective was to identify variations the for preterm neonates 10 national or regional networks participating International Network Evaluating Outcomes (iNeo) neonates. <b><i>Method:</i></b> Online, pre-piloted questionnaires about were sent directors 390 tertiary international...
Abstract Aim We surveyed care practices for critically ill very preterm infants admitted to neonatal intensive units (NICUs) in the International Network Evaluating Outcomes Neonates (iNeo) identify differences relevant outcome comparisons. Methods conducted an online survey on and with severe intracranial haemorrhage (ICH). The was distributed 2015 representatives of 390 NICUs 11 countries. Survey replies were compared network incidence death ICH born between 23 0/7 28 6/7 weeks gestation...
To assess associations between 5 min Apgar score and mortality severe neurological injury (SNI) to report test characteristics in preterm neonates.Retrospective cohort study of neonates 240 286 weeks' gestation born 2007 2016 admitted neonatal units 11 high-income countries.5 score.In-hospital SNI defined as grade 3 or 4 periventricular/intraventricular haemorrhage periventricular leukomalacia. Outcome rates were calculated for each compared after adjustment. The diagnostic ORs value from 0...