A5101501112- Neurological Disease Mechanisms and Treatments
- Traditional Chinese Medicine Studies
- Acute Ischemic Stroke Management
- Clinical practice guidelines implementation
- Neurological Disorders and Treatments
- Medical Research and Treatments
- Traditional Chinese Medicine Analysis
- Plant-based Medicinal Research
- Ginkgo biloba and Cashew Applications
- Stroke Rehabilitation and Recovery
- Alzheimer's disease research and treatments
- RNA modifications and cancer
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer, Hypoxia, and Metabolism
- Biochemical and biochemical processes
- Biochemical effects in animals
- Health Policy Implementation Science
- Dementia and Cognitive Impairment Research
- Neuroblastoma Research and Treatments
- Plant biochemistry and biosynthesis
- Parkinson's Disease Mechanisms and Treatments
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- Calcium signaling and nucleotide metabolism
- Mitochondrial Function and Pathology
Xiyuan Hospital
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Hubei 672 Orthopedics Hospital of Traditional Chinese Medicine and Western Medicine
2014
Background Tension-type headache (TTH) is the most common type of and second health-related complaint among children adults. Traditional Chinese medicine (TCM) offers unique therapeutic benefits in treating TTH. However, lack standardized evidence—such as inconsistencies outcome selection reporting clinical studies, a consensus on outcomes measures, high risks selective bias, missing data—has limited development robust evidence supporting efficacy TCM Therefore, establishing core set (COS)...
Introduction The integration of traditional Chinese medicine (TCM) and Western has demonstrated effectiveness in the primary prevention stroke. Therefore, our study aims to utilize TCM syndromes alongside conventional risk factors as predictive variables construct a machine learning model for assessing new-onset Methods We conducted ten-year follow-up encompassing 4,511 participants from multiple community hospitals. dependent variable was occurrence stroke, while independent included age,...
Background: Parkinson’s disease (PD) is the second most common neurodegenerative worldwide, yet as of currently, there no disease-modifying therapy that could delay its progression. Paeonia lactiflora Pall. frequently used herb in formulas for PD Traditional Chinese Medicine and also a potential neuroprotective agent diseases, while mechanisms remain poorly understood. In this study, we aim to explore underlying mechanism P. treating utilizing network pharmacology approach. Methods: The...
Abstract Objective The purpose of this study was to evaluate the effect astaxanthin (AST) on cognition function, inflammatory response and oxidative stress in vascular dementia (VD) mice. Method VD mice model established by left unilateral common carotid arteries occlusion (LUCCAO). Following LUCCAO, AST intragastrically administered for 30 days. Object recognition test morris water maze were used cognitive function. Hematoxylin eosin staining performed observe hippocampal neuron structure....
As important immune cells, macrophages are a key factor involved in maintaining the homeostasis of pulmonary microenvironment. Under different conditions, with high plasticity can be polarized into classically activated(M1) and selectively activated(M2) macrophages, which have pro-inflammatory anti-inflammatory effects, respectively. M1/M2 phenotype is associated occurrence development diseases. A variety information molecules cytokines polarization play role regulating phenotypes diseases,...
The present clinical practice guideline was written by experts organized the special group of key projects in 13 th five-year plan period China Academy Chinese Medical Sciences based on standards and procedures World Health Orga-nization Handbook for Guideline Development, with evidence-based, consensus-based, experience-based principle as a guide. On basis traditional medicine(TCM) research migraine, following idea method evidence-based medicine, well expert experience, current best...
The objective cognitive trajectory in patients with post-stroke subjective complaints (SCC) over time remained unknown. We investigated outcomes SCC within 1 year after stroke, and determined factors associated recovery.This study included 599 a clinical diagnosis of evidence deficits including Clinical Dementia Rating Scale (CDR) = 0.5, Montreal Cognitive Assessment (MoCA) score <26, Mini-Mental State Examination >17 (illiterate) or >20 (primary school) >24 (junior school above)....
In this study, common prescriptions were retrieved from existing data in multiple ways to determine the selection principle of formulas traditional Chinese medicine(TCM) clinical practice guidelines. Taking guidelines TCM for migraine as an example, we searched migraines National Essential Medicine List, Drug Catalog Basic Medical Insurance, Work-related Injury and Maternity Pharmacopoeia, three teaching materials two guidelines, also electronically CNKI, VIP, WanFang about famous experience...
To investigate the role of RNA m6A methylation in mediating cerebellar dysplasia through analyzing phenotypes mouse cerebella and expression several key regulators upon hypobaric hypoxia treatment.
To analyze the use of outcome indicators randomized controlled trial(RCT) acupuncture in treatment acute ischemic stroke recent three years, so as to provide a basis for building study on core with acupuncture. The RCTs years were collec-ted through computer retrieval eight Chinese and English databases two clinical trial registries at home abroad. Literature was screened out, data extracted. Risk assessment bias tool Cochrane 6.1 used risk assessment, summarized analyzed. A total 47...