Martin Dvorak

ORCID: 0000-0001-5614-7536
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About
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Research Areas
  • Environmental Toxicology and Ecotoxicology
  • Mercury impact and mitigation studies
  • Trace Elements in Health
  • Freshwater macroinvertebrate diversity and ecology
  • Mollusks and Parasites Studies
  • Heavy metals in environment
  • Fish Ecology and Management Studies
  • Aquatic Invertebrate Ecology and Behavior
  • Environmental DNA in Biodiversity Studies
  • Heavy Metal Exposure and Toxicity
  • Identification and Quantification in Food
  • Physiological and biochemical adaptations

Universität Innsbruck
2017-2024

Metal detoxification is crucial for animals to cope with environmental exposure. In snails, a pivotal role in protection against cadmium (Cd) attributed metallothioneins (MTs). Some gastropod species express, lineage-specific manner, Cd-selective MTs devoted exclusively the binding and of this single metal, whereas other snails possess non-selective MTs, but still show high tolerance Cd. An explanation may be that invertebrates particular also synthetize phytochelatins (PCs), originally...

10.3390/ijms21010007 article EN International Journal of Molecular Sciences 2019-12-18

Abstract The tiny contribution of cadmium (Cd) to the composition earth’s crust contrasts with its high biological significance, owing mainly competition Cd essential zinc (Zn) for suitable metal binding sites in proteins. In this context it was speculated that several animal lineages, protein family metallothioneins (MTs) has evolved specifically detoxify Cd. Although multi-functionality and heterometallic MTs most species does not support such an assumption, there are some exceptions role,...

10.1039/c9mt00259f article EN Metallomics 2020-03-10

Metallothioneins (MTs) are low-molecular-mass, cysteine-rich, metal binding proteins. In most animal species, they involved in homeostasis and detoxification, provide protection from oxidative stress. Gastropod MTs highly diversified, exhibiting unique features adaptations like specificity multiplications of their domains. Here, we show that the MT gene

10.3390/ijms18081747 article EN International Journal of Molecular Sciences 2017-08-11

Terrestrial snails (Gastropoda) possess Cd-selective metallothioneins (CdMTs) that inactivate Cd2+ with high affinity. Most of these MTs are small Cysteine-rich proteins bind 6 equivalents within two distinct metal-binding domains, a binding stoichiometry 3 ions per domain. Recently, unusually large, so-called multi-domain (md-MTs) were discovered in the terrestrial door snail Alinda biplicata (A.b.). The aim this study is to evaluate ability A.b. cope Cd stress and potential involvement...

10.3390/ijms21051631 article EN International Journal of Molecular Sciences 2020-02-27

Diamesa species (Diptera, Chironomidae) are widely distributed in freshwater ecosystems, and their life cycles closely linked to environmental variables such as temperature, water quality, sediment composition. Their sensitivity changes, particularly response pollution habitat alterations, makes them valuable indicators of ecosystem health. The challenges associated with the morphological identification larvae invoke use DNA barcoding for determination. mitochondrial cytochrome oxidase...

10.1371/journal.pone.0298367 article EN cc-by PLoS ONE 2024-02-15

Chironomids (non-biting midges) inhabit almost every wet or semi-wet continental environment on Earth with probably 10,000 different species. Species occurrence and composition are undoubtedly limited by environmental harshness food availability being reflected in their energy stores. Most animals store as glycogen lipid. They enable the to survive adverse situations continue growth, development, reproduction. This general statement is also true for insects particularly chironomid larvae....

10.1016/j.cbpa.2023.111477 article EN cc-by Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology 2023-07-05

In most organisms, the concentration of free Zn2+ is controlled by metallothioneins (MTs). contrast, no significant proportions are bound to MTs in slug, Arion vulgaris. Instead, this species possesses cytoplasmic low-molecular-weight (LMW Zn) binding compound that divert these metal ions into pathways uncoupled from MT metabolism. accumulated midgut gland calcium cells vulgaris, where they associate with a ligand an apparent molecular mass ~ 2,000 Da. Mass spectrometry semi-purified LMW Zn...

10.1038/s41598-019-56577-7 article EN cc-by Scientific Reports 2019-12-27

Chironomids of the genus Diamesa (Meigen, 1835, Diptera: Chironomidae) inhabit cold, oxygen-rich running waters. We have investigated presence and other freshwater macroinvertebrates at 22 stream sampling sites in 3 European high mountain regions (the Central Pyrenees, Ötztal Alps, Tatra Mountains) to establish suitable temperature conditions for dominance. It has been generally accepted that their abundance was linked glaciers; however, we shown Mountains, where there are no glaciers,...

10.1093/ee/nvae052 article EN Environmental Entomology 2024-06-13
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