A5009180047- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
- Diabetes and associated disorders
- Adrenal Hormones and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Thyroid Disorders and Treatments
- Hormonal Regulation and Hypertension
- Metabolism, Diabetes, and Cancer
- Neurological and metabolic disorders
- Pancreatic and Hepatic Oncology Research
- melanin and skin pigmentation
- Lymphoma Diagnosis and Treatment
- Folate and B Vitamins Research
- Electrolyte and hormonal disorders
- Migraine and Headache Studies
- Ion channel regulation and function
- Diabetes Management and Research
- Platelet Disorders and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Thyroid Cancer Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Hormonal and reproductive studies
- Lipoproteins and Cardiovascular Health
Hospital da Luz
2022-2024
Hospital de Egas Moniz
2016-2024
St. George's University
2024
Universidade Nova de Lisboa
2024
Centro Hospitalar de Lisboa Ocidental
2017-2024
Florida International University
2024
Nova Medical (United States)
2023
Hospital of St. Francis Xavier
2023
Central University of Venezuela
2023
University of Lisbon
2023
Abstract A case of acquired von Willebrand disease (AvWD) associated with an IgA lambda multiple myeloma is reported. No form inhibitor could be detected. SDS‐agarose gel electrophoresis patterns factor (vWF) both in plasma and platelet lysates were normal but a decrease all‐sized multimers type IA pattern was seen. After 1‐deamino‐8‐D arginine vasopressin (DDAVP) infusion, vWF larger than those seen the resting state appeared patient plasma, which progressively cleared. Indirect...
The burden of COVID-19 infections has been extensively studied in some parts the world. However, emerging economies and particularly Latin America Colombia, research is still incomplete, especially paediatric population. This study aims to investigate children adolescents Colombia understand outcomes COVID-19. a retrospective database analysis 0-17-year-old persons diagnosed with given inpatient or outpatient care at large health maintenance organisation covering 10% entire population from...
The authors describe a case of life-threatening diabetic emergency 25 days after initiation nivolumab (3 mg/kg) for stage 4 lung adenocarcinoma. She was admitted to the department, with hyperglycaemia-related signs and symptoms, such as polyuria, polydipsia, weight loss, confusion, asthenia, dehydration, hypotension Kussmaul respiratory pattern. Her body mass index 21.9 kg/m2 she did not show acanthosis nigricans. Arterial blood gas determination revealed high anion gap metabolic acidaemia...
Portugal is a country with high prevalence of type 2 diabetes (T2D) and cardiovascular disease (CVD). The CVD (CV) risk factors among T2D patients followed in hospitals not known. primary objective this study was to assess the CV hospital setting Portugal. clinical management also assessed. We performed non-interventional, multicenter, cross-sectional retrospective phase. were consecutively invited participate. Data collected retrospectively. A total 715 included study. Mean age duration...
Down syndrome is a frequent clinical entity, being considered one of the most chromosomal aberrations. It characterised by typical phenotype and associated with heterogeneous group organ system-specific abnormalities. The cardiovascular system commonly affected if so, it may be an increased morbidity mortality. Cerebrovascular events in patients are multifactorial, possibly related to congenital heart disease, vascular malformations traditional risk factors. Moyamoya disease rare chronic...
Thyroid lymphomas are rare clinical entities that may result from either the primary intrathyroid de novo or secondary thyroid gland involvement of a lymphoma. Among these, Hodgkin’s subtype is quite uncommon, accounting for 0.6–5% all malignancies. The authors report on 76-year-old female presenting with nodule that, upon surgical excision, was found to be nodular lymphocyte predominant Hodgkin lymphoma thyroid. So far, by this variant has never been reported. Upon reporting case, emphasize...
Parathyroid Carcinoma is a rare malignant neoplasm, accounting for less than 1% of primary hyperparathyroidism cases. carcinomas are characterized by markedly elevated levels PTH, severe hypercalcemia and established target organ damage. The authors report the experience single centre regarding management outcome patients with parathyroid revise relevant literature.Retrospective review all carcinoma evaluated at tertiary oncologic from 1991 until 2021.Seventeen were identified (10 males),...
Introdução: A diabetes mellitus tipo 2 é uma entidade comum, afetando até 13,1% da população portuguesa. Para além das conhecidas complicações micro e macrovasculares, as iatrogenias medicamentosas tornaram-se crescente preocupação contribuindo para observadas alterações recomendações terapêuticas, que cada vez mais privilegiam a segurança em detrimento eficácia. metformina o agente farmacológico de primeira linha na maioria dos doentes com 2, contudo, está descrita associação défice...
Introduction Primary adrenal insufficiency (PAI) is a rare but severe and potentially life-threatening condition. No previous studies have characterized Portuguese patients with PAI. Aims To characterize the clinical presentation, diagnostic workup, treatment follow‐up of confirmed Methods This multicentre retrospective study examined PAI in 12 hospitals. Results We investigated 278 (55.8% were females), mean age 33.6 ± 19.3 years at diagnosis. The most frequent presenting features asthenia...
Summary Granular cell tumours (GCT) are rare, slow-growing, benign neoplasms that usually located in the head and neck. They more frequent female gender typically have an asymptomatic clinical course, being diagnosed only at autopsy. Symptomatic GCT of neurohypophysis exceedingly less than 70 cases described so far. The authors report on a case 28-year-old male presented to Endocrinology clinic with biochemical evidence hypogonadism. He also reported minor headaches without any major visual...
Cushing's syndrome (CS) is a rare clinical entity that results from prolonged exposure to supraphysiological levels of glucocorticoids. It may result adrenocorticotropic hormone (ACTH)-dependent or nondependent stimuli. In very cases, ACTH production does not derive the pituitary gland but an ectopic origin. We present case 51-year-old woman with cushingoid physical features, who was admitted emergency department hypertensive crisis, hyperglycemic state, and severe hypokalemia. During...
Pituitary apoplexy is a rare medico-surgical emergency that stems from an acute expansion of pituitary adenoma infarction or haemorrhage and where the treatment strategy still controversial. Clinical presentation highly variable high index suspicion needed to make diagnosis. Furthermore, in less than half cases, precipitating event identified. We report case 74-year-old female who, after introduction anticoagulation for pulmonary thromboembolism, presented with heralded by adrenal...
Primary adrenal lymphoma is a rare malignancy. It frequently presents bilaterally and with symptoms of insufficiency. Amiodarone may induce secondary organ dysfunction, thyrotoxicosis develops in 15% cases. The symptomatology both conditions nonspecific, especially the elderly, high suspicion index necessary for appropriate diagnosis. A 78-year-old female presented to emergency department confusion, nausea vomiting. She had recently been urinary tract infection, vomiting acute hypochloremic...
Summary Central diabetes insipidus (DI) is a rare clinical entity characterized by low circulating levels of antidiuretic hormone (ADH) presenting with polyuria and volume depletion. Pituitary surgery the most common cause central DI in adults. hypothalamic disease, particularly invasive neoplasms, rarely DI, being idiopathic cases responsible for majority non-surgical cases. HIV patients, especially those poor virulogical control, are prone to development CNS lymphomas. These neoplasms...
Cushing's syndrome is a rare disease that results from prolonged exposure to supraphysiological levels of glucocorticoids. Severe and rapidly progressive cases are often, but not exclusively, attributable ectopic ACTH secretion. Extreme hypercortisolism usually has florid metabolic consequences associated with an increased infectious thrombotic risk. The authors report on case 51-year-old male presented severe secondary ACTH-secreting pituitary macroadenoma, whose diagnostic workup was...
Graves' disease (GD) is associated with primary hyperthyroidism, leading to weight loss before treatment. During the treatment, gain frequently observed, often surpassing initial loss. This study aimed analyze fluctuations in GD patients, focusing on subset of overweight and obese (OAO) individuals, considering significant metabolic implications heightened cardiovascular risk these changes.
This case report describes a patient with large type IV hiatal hernia (HH), notable for exhibiting minimal symptoms, unlike typical cases of similar severity. The experienced only mild discomfort despite significant anatomical displacement, without severe symptoms often seen such hernias. Diagnostic tests confirmed the herniated stomach, but lack like dysphagia defies usual expectations. highlights variability in and clinical presentations HH, stressing need tailored assessment management...
Overweight and obesity are major public health issues with increasing incidence prevalence, affecting more than 50% of the population in developed countries. Due to its complex pathophysiology multifactorial etiology, disease understanding, diagnostic approach management remain suboptimal. Together a structured nutritional intervention physical activity plan, pharmacological treatment has potential magnify weight loss related benefits. Liraglutide is one most effective frequently prescribed...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Paragangliomas and pheochromocytomas are rare catecholamine secreting neoplasms that arise in the extra-adrenal autonomic paraganglia adrenal medulla, respectively. Although typically presenting with paroxysms of headaches, palpitations, diaphoresis hypertension, a broad spectrum clinical manifestations may occur. Diagnosis relies on biochemical studies followed by adequate imaging investigation. Cross sectional morphological functional modalities have improved diagnostic accuracy crucial...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)