A5002196485- Research Data Management Practices
- Biomedical Text Mining and Ontologies
- Scientific Computing and Data Management
- Patient-Provider Communication in Healthcare
- Electronic Health Records Systems
- Health Systems, Economic Evaluations, Quality of Life
- Clinical practice guidelines implementation
- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Chronic Disease Management Strategies
- Healthcare Systems and Technology
- Renal cell carcinoma treatment
- Healthcare Technology and Patient Monitoring
- Health Literacy and Information Accessibility
- Patient Safety and Medication Errors
- Dementia and Cognitive Impairment Research
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Medication Adherence and Compliance
- Mental Health Research Topics
- Treatment of Major Depression
- Sepsis Diagnosis and Treatment
- Artificial Intelligence in Healthcare
- Health disparities and outcomes
- Ethics in Clinical Research
World Health Organization
2022
University of Amsterdam
2014-2020
Amsterdam University Medical Centers
2019-2020
Public Health Service of Amsterdam
2020
Amsterdam UMC Location University of Amsterdam
2013-2018
GGZ inGeest
2012
The Internet is viewed as an important source for health information and a medium patient empowerment. However, little known about how seniors use the in relation to other sources information.The aim was determine which resources who trust information, are preferred, used by different needs.Questions from published surveys were selected based on their relevance study objectives. Autonomy Preference Index assess needs preferences involvement decisions. Invitation participate this online...
Objective: Emerging evidence has shown the potential risks of arterial hyperoxia, but lack a clinical definition and methodologic limitations hamper interpretation relevance previous studies. Our purpose was to evaluate previously used newly constructed metrics hyperoxia systematically assess their association with outcomes in different subgroups ICU. Design: Observational cohort study. Setting: Three large tertiary care ICUs Netherlands. Patients: A total 14,441 eligible ICU patients....
Background Adherence to guidelines pertaining stroke prevention in patients with atrial fibrillation is poor. Decision support systems have shown promise increasing guideline adherence. Aims To improve adherence a non-obtrusive clinical decision system integrated the workflow. Secondly, we seek capture reasons for non-adherence. Design and setting A cluster randomized controlled trial Dutch general practices. Method was developed that implemented properties positively associated...
Recent reports have suggested declining age-specific incidence rates of dementia in high-income countries over time. Improved education and cardiovascular health early age been to be bringing about this effect. The aim study was estimate the trend primary care records from a large population Netherlands.A dynamic cohort representative Dutch composed using general practice registration networks (GPRNs) across country. Data regarding were obtained general-practitioner-recorded diagnosis within...
<h3>Objectives</h3> Recent guidelines advocate accelerated provider-initiated HIV testing by general practitioners (GPs). We aimed to identify the number of patient consultations in six practices South-East Amsterdam, and incidence indicator conditions reported their medical files prior diagnosis. <h3>Methods</h3> A cross-sectional search an electronic practice database. used a case–control design those most associated with HIV-positive status. <h3>Results</h3> included 102 cases diagnosed...
Background Many studies have investigated the use of clinical decision support systems as a means to improve care, but thus far failed show significant effects on patient-related outcomes. We developed system that attempted address issues were identified in these studies. The was implemented Dutch general practice and designed be both unobtrusive respond real time. Despite our efforts, usage low. In current study we perform mixed methods evaluation identify remediable barriers which led...
Existing methods to make data Findable, Accessible, Interoperable, and Reusable (FAIR) are usually carried out in a post hoc manner: after the research project is conducted collected. De-novo FAIRification, on other hand, incorporates FAIRification steps process of project. In medical research, often collected stored via electronic Case Report Forms (eCRFs) Electronic Data Capture (EDC) systems. By implementing de novo such system, reusability and, thus, scalability across projects can be...
The industry sector is a very large producer and consumer of data, many companies traditionally focused on production or manufacturing are now relying the analysis amounts data to develop new products services. As sources needed distributed outside company, FAIR will have major impact, both by reducing existing internal silos enabling efficient integration with external (public commercial) data. Many still in early phases “FAIRification”, providing opportunities for SMEs academics apply...
Abstract Background Patient data registries that are FAIR—Findable, Accessible, Interoperable, and Reusable for humans computers—facilitate research across multiple resources. This is particularly relevant to rare diseases, where often scarce scattered. Specific questions can be asked FAIR disease other resources without physically combining the data. Further, implies well-defined, transparent access conditions, which supports making sensitive as open possible closed necessary. Results We...
To determine adequacy of antithrombotic treatment in patients with non-valvular atrial fibrillation. risk factors for under- and over-treatment.Retrospective, cross-sectional study electronic health records from 36 general practitioners 2008.General practice the Netherlands.Primary care physicians (n = 36) 981) aged 65 years over.Rates adequate, under over-treatment, over-treatment.Of 981 included a mean age 78, 18% received no (under-treatment), 13% antiplatelet drugs 69% oral...
We developed a web-based question prompt sheet (QPS) to support information provision of health-related quality life (HRQL) topics after oesophageal cancer surgery. The QPS was evaluated and updated in three consecutive studies. In Study 1, eight patients were guided using the QPS. Feasibility assessed by cognitive walkthrough, questionnaire interview. obtained 430 notes (217 negative, 213 positive) patients' actions or remarks, 91 suggestions. With minor support, most able use 2, forty...
The FAIR Data Principles are being rapidly adopted by many research institutes and funders worldwide. This study aimed to assess the awareness attitudes of clinical researchers support staff regarding data FAIRification. A questionnaire was distributed in six Dutch University Medical Centers Electronic Capture platform users. 164 21 members completed questionnaire. 62.8% 81.0% currently undertaking at least some effort achieve any aspect FAIR, 11.0% 23.8%, respectively, address all aspects....
Patients with atrial fibrillation (AF) are at increased risk for stroke. Antithrombotic treatment reduces this risk. consists of either administration oral anticoagulants (OAC) or the provision an antiplatelet drug. International guidelines provide advice on preferred treatment, thereby balancing risks and benefits OAC. However, adherence to these is reported be as low 50%. There paucity in research why rates low. Recent studies have shown decision support systems can improve guideline...
Information in Electronic Health Records is largely stored as unstructured free text. Natural language processing (NLP), or Medical Language Processing (MLP) medicine, aims at extracting structured information from text, and less expensive time-consuming than manual extraction. However, most algorithms MLP are institution-specific address only one clinical need, thus cannot be broadly applied. In addition, systems do not detect concepts misspelled text attribute relationships between...
Previous efforts such as Assessing Care of Vulnerable Elders (ACOVE) provide quality indicators for assessing the care elderly patients, but thus far little has been done to leverage this knowledge improve these patients. We describe a clinical decision support system general practitioner (GP) adherence ACOVE and protocol investigating impact on GPs’ rules. propose two randomized controlled trials among group Dutch GP teams indicators. In both provides un-intrusive feedback appearing...
Despite the promise of decision support for improving care, alerts are often overridden or ignored. We evaluated Dutch general practitioners' intention to accept in a proposed implementation based on clinical rules regarding care elderly patients, and their reasons wanting not support. developed survey literature structured interviews distributed it all doctors who would receive (n = 43), which 65 percent responded. The consisted six questions each 20 rules. concerns about interruption,...
Abstract Background Patient data registries that are FAIR - Findable, Accessible, Interoperable, and Reusable for humans computers facilitate research across multiple resources. This is particularly relevant to rare diseases, where often scarce scattered. Specific questions can be asked disease other resources without physically combining the data. Results We successfully developed implemented a process of making registry vascular anomalies from its conception de novo . Here, we describe...
Introduction Existing methods to make data Findable, Accessible, Interoperable, and Reusable (FAIR) are usually carried out in a post-hoc manner: after the research project is conducted collected. De-novo FAIRification, on other hand, incorporates FAIRification steps process of project. In medical research, often collected stored via electronic Case Report Forms (eCRFs) Electronic Data Capture (EDC) systems. By implementing de-novo such system, reusability and, thus, scalability across...