A5013982476- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Aging and Gerontology Research
- Mental Health Research Topics
- Stress Responses and Cortisol
- Cardiac Health and Mental Health
- Frailty in Older Adults
- Bipolar Disorder and Treatment
- Electroconvulsive Therapy Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Treatment of Major Depression
- Mental Health Treatment and Access
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Tryptophan and brain disorders
- Health Systems, Economic Evaluations, Quality of Life
- Psychological Well-being and Life Satisfaction
- Nutrition and Health in Aging
- Child and Adolescent Psychosocial and Emotional Development
- Attention Deficit Hyperactivity Disorder
- Intergenerational Family Dynamics and Caregiving
- Eating Disorders and Behaviors
- Hormonal Regulation and Hypertension
- Intensive Care Unit Cognitive Disorders
- Elder Abuse and Neglect
GGZ inGeest
2013-2022
Amsterdam UMC Location Vrije Universiteit Amsterdam
2012-2022
Amsterdam Public Health
2010-2021
Amsterdam University Medical Centers
2018-2021
Vrije Universiteit Amsterdam
2007-2021
University Medical Center
2006-2020
Amsterdam Neuroscience
2017
GGD Amsterdam
2005-2015
Radboud University Medical Center
2014
University Medical Center Groningen
2014
Comorbidity of depressive and anxiety disorders is common has been shown to be a consistent predictor chronicity. patterns among specific have not extensively reported. This study examines comorbidity temporal sequencing separate using data from large psychiatric cohort.Baseline (N = 1,783) the Netherlands Study Depression Anxiety, collected between September 2004 February 2007, were used. Current lifetime rates for (DSM-IV-TR criteria) calculated. Associations with sociodemographic,...
Purpose.: We assessed the prevalence of subthreshold depression and anxiety, major depressive, dysthymic, anxiety disorders (panic disorder, agoraphobia, social phobia, general disorder) in visually impaired older adults compared these estimates with those normally sighted peers. Methods.: Cross-sectional data were analyzed based on telephone interviews aged ≥ 60 years (n = 615) a visual acuity 0.30 logMAR (20/40 Snellen) best eye from outpatient low vision rehabilitation centers,...
The Longitudinal Aging Study Amsterdam (LASA) is an ongoing longitudinal study of older adults in the Netherlands, which started 1992. LASA focused on determinants, trajectories and consequences physical, cognitive, emotional social functioning. based a nationally representative sample aged 55 years over. findings have been reported over 450 publications so far (see www.lasa-vu.nl ). In this article we describe background design study, provide update methods. addition, summary major from...
<b>Objective: </b> To assess whether serum levels of the inflammatory proteins α<sub>1</sub>-antichymotrypsin (ACT), C-reactive protein (CRP), interleukin-6 (IL-6), and albumin are associated with cognitive decline in older persons. <b>Methods: The study sample consisted 1,284 participants Longitudinal Aging Study Amsterdam, aged 62 to 85 years. Cognition was assessed on general cognition (Mini-Mental State Examination [MMSE]), memory (Auditory Verbal Learning Test), fluid intelligence...
Recent evidence suggests that the metabolic syndrome and inflammation affect cognitive decline in old age they reinforce each other. However, it is not known what roles of individual components on cognition are.The sample consisted 1,183 participants Longitudinal Aging Study Amsterdam who were aged 65-88 years. Metabolic (U.S. National Cholesterol Education Program definition) its inflammatory markers C-reactive protein (CRP) alpha1-antichymotrypsin (ACT) assessed. Cognitive assessments...
<b><i>Objective: </i></b> To investigate to what extent subjective memory complaints and <i>APOE</i>-ε4 allele carriage predict future cognitive decline in cognitively intact elderly persons, by evaluating both their separate combined effects. <b><i>Methods: We selected 1,168 subjects from the population-based Longitudinal Aging Study Amsterdam who were 62 85 years of age had no obvious impairment at baseline (Mini-Mental State Examination [MMSE] score, ≥27). Memory <i>APOE</i> phenotypes...
The aging society will bring an increase in the number of people with dementia living community. This mean a greater demand on care and welfare services to deliver efficient customized care, which requires thorough understanding subjective objective needs. study aims assess needs community-dwelling as reported by themselves their informal carers. also give insight into service use gaps between availability services.236 322 carers were interviewed separately. (Un)met assessed using Camberwell...
OBJECTIVES: (1) To assess the prevalence and consequences of chronic verbal aggression, physical financial mistreatment, neglect in a community‐based sample; (2) to investigate circumstances that led abuse ways which victims handled problem. DESIGN: Prevalence was assessed population‐based sample 1797 older people living independently Amsterdam, Netherlands. In follow‐up study 1 year later, were questioned again about background abuse. RESULTS: The 1‐year elder 5.6%. various types was:...
Obsessive-compulsive disorder (OCD) and social anxiety (SAD) frequently co-occur in persons with autism spectrum (ASD). We studied which features distinguish 'pure' disordered patients from those co-morbid ASD.In a case-controlled design groups were matched for age, sex educational level, OCD or SAD ASD compared (i.e. without ASD) OCD, control group, using the Autism Questionnaire (AQ), Yale-Brown Obsessive-Compulsive Scales, Liebowitz Social Anxiety Scale, Beck Inventory questions on...
Little is known about the prevalence of attention-deficit hyperactivity disorder (ADHD) among older adults.To estimate syndromatic and symptomatic DSM-IV ADHD diagnosis in adults The Netherlands.Data were used from Longitudinal Aging Study Amsterdam (LASA). At baseline, 1494 participants screened with an questionnaire 231 respondents a structured diagnostic interview was administered. weighted calculated.The estimated rate 2.8%; for 4.2%. Younger elderly (60-70 years) reported significantly...
To study late-life depression and its unfavourable course co morbidities in The Netherlands.We designed the Netherlands Study of Depression Older Persons (NESDO), a multi-site naturalistic prospective cohort which makes it possible to examine determinants, consequences depressive disorders older persons over period six years, compare these with those earlier adulthood.From 2007 until 2010, NESDO consortium has recruited 510 depressed non (≥ 60 years) at 5 locations throughout Netherlands....
To what extent endogenous subclinical thyroid disorders contribute to impaired physical and cognitive function, depression, mortality in older individuals remains a matter of debate.A population-based, prospective cohort the Longitudinal Aging Study Amsterdam.TSH and, if necessary, thyroxine triiodothyronine levels were measured aged 65 years or older. Participants classified according clinical categories function. with overt disease use medication excluded, leaving 1219 participants for...
Background: Recently, the LIfestyle for BRAin health (LIBRA) index was developed to assess an individual’s prevention potential dementia. Objective: We investigated predictive validity of LIBRA incident dementia in midlife, late life, and oldest-old. Methods: 9,387 non-demented individuals were recruited from European population-based DESCRIPA study. An calculated solely based on modifiable risk factors: depression, diabetes, physical activity, hypertension, obesity, smoking,...
We aimed to examine the course of depression during 2-year follow-up in a group clinically depressed older persons. Subsequently, we studied which socio-demographic and clinical characteristics predict diagnoses at follow-up.Data were used from Netherlands Study Depression Older persons (NESDO; N = 510). Diagnoses DSM-IV-TR criteria available 285 patients baseline follow-up. Severity depressive symptoms, as assessed with Inventory Depressive Symptoms (IDS), was obtained 6-monthly postal...
Risk factors for cognitive decline might depend on chronological age. The aim of the study was to explore age dependency risk in cognitively healthy subjects aged 55–85 years at baseline. We included 2527 from Longitudinal Aging Study Amsterdam (LASA). Median follow-up 9.1 (IQR: 3.2–19.0) years. association genetic and cardiovascular factors, depressive symptoms, inflammation markers lifestyle with MMSE memory function tested using spline regression analyses. Subjects were average 70.1 (SD...