- Mental Health Treatment and Access
- Health disparities and outcomes
- Mental Health Research Topics
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Aging and Gerontology Research
- Dementia and Cognitive Impairment Research
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Cardiac Health and Mental Health
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Tryptophan and brain disorders
- Health, psychology, and well-being
- Mental Health and Psychiatry
- Suicide and Self-Harm Studies
- Attention Deficit Hyperactivity Disorder
- Psychiatric care and mental health services
- Digital Mental Health Interventions
- Stress Responses and Cortisol
- Employment and Welfare Studies
- Personality Disorders and Psychopathology
- Functional Brain Connectivity Studies
- Electroconvulsive Therapy Studies
- Health and Wellbeing Research
- Psychosomatic Disorders and Their Treatments
Vrije Universiteit Amsterdam
2016-2025
Amsterdam University Medical Centers
2011-2025
Amsterdam Neuroscience
2014-2025
Amsterdam UMC Location Vrije Universiteit Amsterdam
2014-2024
GGZ inGeest
2015-2024
University of Amsterdam
1997-2024
Public Health Service of Amsterdam
2012-2024
University Medical Center
2007-2022
Cal Humanities
2022
Menlo School
2021
The Center for Epidemiologic Studies Depression scale (CES-D) has been widely used in studies of late-life depression. Psychometric properties are generally favourable, but data on the criterion validity CES-D elderly community-based samples lacking. In a sample older (55-85 years) inhabitants Netherlands, 487 subjects were selected to study CES-D. Using 1-month prevalence major depression derived from Diagnostic Interview Schedule (DIS) as criterion, weighted sensitivity was 100%;...
Abstract Background Depression and cardiovascular diseases are both common among elderly. is suspected to be an independent risk factor for the onset of coronary heart disease, yet it not clear what extent if depression also associated with other circulatory system. Aims To estimate as various (CVD) explore effects heterogeneity methodological quality. Method Meta‐analyses meta‐regression analyses longitudinal cohort case‐control studies reporting at baseline CVD outcomes follow‐up. Data...
Depression may be a potential risk factor for subsequent cardiac death. The impact of depression on mortality has been suggested to depend disease status, and stronger among patients. This study examined compared the effect in community-dwelling persons with without disease.A cohort 2847 men women aged 55 85 years was evaluated 4 years. Major defined according psychiatric DSM-III criteria. Minor by Center Epidemiologic Studies-Depression Scale scores 16 or higher. Effects minor major were...
Abstract The Netherlands Study of Depression and Anxiety (NESDA) is a multi‐site naturalistic cohort study to: (1) describe the long‐term course consequences depressive anxiety disorders, (2) to integrate biological psychosocial research paradigms within an epidemiological approach in order examine (interaction between) predictors consequences. Its design eight‐year longitudinal among 2981 participants aged 18 through 65 years. sample consists 1701 persons with current (six‐month recency)...
Comorbidity of depressive and anxiety disorders is common has been shown to be a consistent predictor chronicity. patterns among specific have not extensively reported. This study examines comorbidity temporal sequencing separate using data from large psychiatric cohort.Baseline (N = 1,783) the Netherlands Study Depression Anxiety, collected between September 2004 February 2007, were used. Current lifetime rates for (DSM-IV-TR criteria) calculated. Associations with sociodemographic,...
Background In an 11-country European collaboration, 14 population-based surveys included 21 724 subjects aged ⩾65 years. Most participating centres used the Geriatric Mental State (GMS), but other measures were also used. Aims To derive from these instruments a common depression symptoms scale, EURO–D, to allow comparison of risk factor profiles between centres. Method Common items identified instruments. Algorithms for fitting GMS derived by observation item correspondence or expert...
OBJECTIVE: The purpose of this study was to examine the comorbidity and communality risk factors associated with major depressive disorder anxiety disorders in later life. METHOD: A random age- sex-stratified community-based sample (N=3,056) elderly (age 55–85 years) Netherlands studied. two-stage screening design used, Center for Epidemiologic Studies Depression Scale as a instrument National Institute Mental Health Diagnostic Interview Schedule criterion instrument. Risk were measured...
<h3>Background</h3> Known risk factors for Alzheimer9s disease and other dementias include medical conditions, genetic vulnerability, depression, demographic mild cognitive impairment. The role of feelings loneliness social isolation in dementia is less well understood, prospective studies including these are scarce. <h3>Methods</h3> We tested the association between (living alone, unmarried, without support), incident a cohort study among 2173 non-demented community-living older persons....
The association between depression and mortality in older community-dwelling populations is still unresolved. This study determined the effect of both minor major on examined role confounding explanatory variables this relationship.A cohort 3056 men women from Netherlands aged 55 to 85 years were followed up for 4 years. Major was defined according DSM-III criteria by means Diagnostic Interview Schedule. Minor as clinically relevant (defined a Center Epidemiologic Studies Depression score >...
Objective. To study the prevalence and risk factors of anxiety disorders in older (55–85) population The Netherlands. Method. Longitudinal Aging Study Amsterdam (LASA) is based on a random sample 3107 adults, stratified for age sex, which was drawn from community registries 11 municipalities three regions Anxiety were diagnosed using Diagnostic Interview Schedule two-stage screening design. under comprise vulnerability, stress network-related variables. Both bivariate multivariate...
Background Data on the duration of major depressive episodes (MDE) in general population are sparse. Aims To assess MDE and its clinical socio-demographic determinants a study group drawn from with newly originated depression. Method The Netherlands Mental Health Survey Incidence Study is prospective epidemiological survey adult ( n=7076 ), using Composite International Diagnostic Interview. Duration over 2 years was assessed Life Chart Results median 3.0 months; 50% participants recovered...
Although psychotherapy and antidepressant medication are efficacious in the treatment of depressive anxiety disorders, it is not known whether they equally for all types antidepressants each disorder. We conducted a meta-analysis studies which were directly compared disorders. Systematic searches bibliographical databases resulted 67 randomized trials, including 5,993 patients that met inclusion criteria, 40 focusing on disorders 27 The overall effect size indicating difference between...
Depression has incidentally been related to altered levels of 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH), but this relation never studied systematically.To determine in a large population-based cohort whether there is an association between depression 25(OH)D PTH levels.Population-based study (Longitudinal Aging Study Amsterdam).One thousand two hundred eighty-two community residents aged 65 95 years.The Netherlands.Depression was measured using self-reports (Center for...
<h3>Background</h3> Accurate assessment of the natural history late-life depression requires frequent observation over time. In later life, depressive disorders fulfilling rigorous diagnostic criteria are relatively rare, while subthreshold common. The primary aim was to study depression, systematically comparing those who did with not fulfill criteria. <h3>Methods</h3> Within Longitudinal Aging Study Amsterdam, a large cohort depressed elderly persons (n = 277) identified and followed up...
The Longitudinal Aging Study Amsterdam (LASA) was initiated by the Dutch Ministry of Welfare, Health and Culture (currently Health, Welfare Sports). By end 1980s, ministry officials recognized that ageing would be a major demographic driving force, shaping need for health care in population near future. Therefore, they became increasingly interested process ageing-related determinants health-care use, wanted to develop policies older people Netherlands who were extra support. Maintaining...