A5032227732- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Sleep and related disorders
- Treatment of Major Depression
- Mental Health Treatment and Access
- Psychosomatic Disorders and Their Treatments
- Tryptophan and brain disorders
- Functional Brain Connectivity Studies
- Hormonal Regulation and Hypertension
- Cardiac Health and Mental Health
- Optimism, Hope, and Well-being
- Diet and metabolism studies
- Mental Health and Psychiatry
- Dementia and Cognitive Impairment Research
- Health Systems, Economic Evaluations, Quality of Life
- Attention Deficit Hyperactivity Disorder
- Bipolar Disorder and Treatment
- Health, psychology, and well-being
- Health disparities and outcomes
- Complementary and Alternative Medicine Studies
- Neurotransmitter Receptor Influence on Behavior
- Pain Management and Placebo Effect
IQ Samhällsbyggnad
2024
Leiden University Medical Center
2011-2023
Leiden University
2007-2016
Maastricht University Medical Centre
2016
Alrijne Ziekenhuis
1993-2016
GGZ Rivierduinen
2006-2014
J.P. Morgan
2012
Loyola University Medical Center
2011-2012
University Medical Center Groningen
2009-2010
Erasmus University Rotterdam
2010
Abstract The Netherlands Study of Depression and Anxiety (NESDA) is a multi‐site naturalistic cohort study to: (1) describe the long‐term course consequences depressive anxiety disorders, (2) to integrate biological psychosocial research paradigms within an epidemiological approach in order examine (interaction between) predictors consequences. Its design eight‐year longitudinal among 2981 participants aged 18 through 65 years. sample consists 1701 persons with current (six‐month recency)...
Comorbidity of depressive and anxiety disorders is common has been shown to be a consistent predictor chronicity. patterns among specific have not extensively reported. This study examines comorbidity temporal sequencing separate using data from large psychiatric cohort.Baseline (N = 1,783) the Netherlands Study Depression Anxiety, collected between September 2004 February 2007, were used. Current lifetime rates for (DSM-IV-TR criteria) calculated. Associations with sociodemographic,...
<h3>Context</h3> There is a central belief that depression associated with hyperactivity of the hypothalamic-pituitary-adrenal axis, resulting in higher cortisol levels. However, results are inconsistent. <h3>Objective</h3> To examine whether there an association between and various indicators large cohort study. <h3>Design, Setting, Participants</h3> Data from 1588 participants Netherlands Study Depression Anxiety who were recruited community, general practice care, specialized mental...
Hovens JGFM, Wiersma JE, Giltay EJ, van Oppen P, Spinhoven Penninx BWJH, Zitman FG. Childhood life events and childhood trauma in adult patients with depressive, anxiety comorbid disorders vs. controls. Objective: To investigate the association between events, presence of anxiety, depressive or adulthood. Method: Data are from 1931 participants Netherlands Study Depression Anxiety (NESDA). included divorce parents, early parental loss ‘placed care’, whereas was assessed as experienced...
Background: Major depression is known to be related higher cardiovascular mortality.However, epidemiological data regarding dispositional optimism in relation mortality are scanty.Objective: To test whether subjects who optimistic live longer than those pessimistic.Design: Our analysis formed part of a prospective population-based cohort study the Netherlands (Arnhem Elderly Study).Setting: General community.Participants: aged 65 85 years (999 men and women) completed 30-item validated Dutch...
<h3>Context</h3> It has been hypothesized that depression is associated with lower heart rate variability and decreased cardiac vagal control. This may play an important role in the risk of cardiovascular disease among depressed individuals. <h3>Objective</h3> To determine whether was individuals than healthy controls a large adult sample. <h3>Design</h3> Cross-sectional analyses from cohort study. <h3>Setting</h3> The Netherlands Study Depression Anxiety. <h3>Participants</h3> Two thousand...
<h3>Context</h3> Major depressive disorder (MDD), panic disorder, and social anxiety are among the most prevalent frequently co-occurring psychiatric disorders in adults may have, at least part, a common etiology. <h3>Objective</h3> To identify unique shared neuroanatomical profile of depression anxiety, controlling for illness severity, medication use, sex, age onset, recurrence. <h3>Design</h3> Cross-sectional study. <h3>Setting</h3> Netherlands Study Depression Anxiety....
Whether course trajectories of depressive and anxiety disorders are different, remains an important question for clinical practice informs future psychiatric nosology. This longitudinal study compares in terms diagnostic symptom trajectories, examines prognostic factors.Data from 1209 and/or patients residing primary specialized care settings, participating the Netherlands Study Depression Anxiety. Diagnostic Life Chart Interviews provided 2-year information.Course was more favorable pure...
The present study compared blood pressure levels between subjects with clinical anxiety and depressive disorders healthy controls. Cross-sectional data were obtained in a large cohort study, the Netherlands Study of Depression Anxiety (N=2981). Participants classified as controls (N=590) or currently remittedly depressed anxious (N=2028), which 1384 not 644 using antidepressants. Regression analyses calculated contributions antidepressant use to diastolic systolic pressures, after...
To examine the association between several subtypes of anxiety disorders and various cortisol indicators in a large cohort study. Anxiety have been suggested to be linked hypothalamic-pituitary-adrenal (HPA) axis activity, although results are scarce inconsistent. No earlier studies examined consistency HPA findings across whether associations state or trait dependent.Data derived from 1427 participants Netherlands Study Depression Anxiety. Three groups were compared: 342 control without...
Hovens JGFM, Giltay EJ, Wiersma JE, Spinhoven P, Penninx BWJH, Zitman FG. Impact of childhood life events and trauma on the course depressive anxiety disorders. Objective: Data impact clinical disorders are limited. Method: Longitudinal data were collected from 1209 adult participants in Netherlands Study Depression Anxiety (NESDA). Childhood at baseline assessed with a semi‐structured interview after 2 years DSM‐IV‐based diagnostic Life Chart Interview. Results: At baseline, 18.4% reported...
Article AbstractObjective: The heterogeneity of depression in the current classification system remains a point discussion psychiatric field, despite previous efforts to subclassify depressive disorders. Data-driven techniques may help come more empirically based classification. This study aimed identify subtypes within large cohort subjects with depression. Method: Baseline data from 818 persons DSM-IV diagnosis major disorder or minor who participated Netherlands Study Depression and...
Cutaneous allodynia is a common feature accompanying migraine attacks and considered clinical marker for central sensitization. In longitudinal study, we wanted to investigate if in patients predictor of increasing frequency days. We included 3029 well-defined, web-based (86% female, mean age 42.8 ± 11.4 years, 61% without aura). Questionnaires on characteristics (including allodynia), depression demographic factors were applied. The number days was measured twice. Multivariate regression...
Stress is suggested to lead metabolic dysregulations as clustered in the syndrome, but underlying biological mechanisms are not yet well understood.We examined relationship between two main str systems, autonomic nervous system and hypothalamic-pituitary-adrenal (HPA) axis, with syndrome its components.The design was baseline data (yr 2004-2007) of a prospective cohort: Netherlands Study Depression Anxiety (NESDA).The study comprised general community, primary care, specialized mental health...
Mineralocorticoid receptors (MR) mediate the action of aldosterone on sodium resorption in kidney tubular cells, but brain they respond to glucocorticoid cortisol stress regulation and cognitive processes.The objective study was investigate role MR gene variant I180V neuroendocrine response a psychosocial stressor electrolyte regulation.Associations between MRI180V outcome variables healthy cohort subjected challenge (Trier Social Stress Test) mild hypertensive exposed acute salt loading...
<h3>Background:</h3> Dispositional optimism, defined in terms of life engagement and generalized positive outcome expectancies for one's future, may be related to lower cardiovascular mortality. We aimed determine whether dispositional optimism is a stable trait over time it independently mortality elderly men. <h3>Methods:</h3> In cohort study with follow-up 15 years, we included 545 (61.4%) 887 men, aged 64 84 who were free preexisting disease cancer had complete data on risk factors...