A5007281939- Mosquito-borne diseases and control
- Malaria Research and Control
- Zoonotic diseases and public health
- Global Maternal and Child Health
- Fungal Infections and Studies
- Tuberculosis Research and Epidemiology
- Parasites and Host Interactions
- Antifungal resistance and susceptibility
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Viral Infections and Outbreaks Research
- HIV, Drug Use, Sexual Risk
- Diagnosis and treatment of tuberculosis
- Drug-Induced Hepatotoxicity and Protection
- COVID-19 Clinical Research Studies
- Infectious Diseases and Tuberculosis
- Hepatitis C virus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycobacterium research and diagnosis
- Long-Term Effects of COVID-19
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
- Heavy Metal Exposure and Toxicity
- Infectious Encephalopathies and Encephalitis
- Amoebic Infections and Treatments
Anton de Kom University of Suriname
2021-2025
Faculdades Oswaldo Cruz
2024
Multi Electrical System (Suriname)
2013-2024
Academic Hospital Paramaribo
2013-2023
Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão
2022
Leiden University
2000
Radboud University Nijmegen
1991-1996
Malaria is endemic in French Guiana, an overseas territory of France on the Guiana Shield. Since 2005, notified malaria cases are decreasing. However, new data show that affects many Brazilian gold miners working illegally majority whom not counted official data. In addition, one major concern usual practice improper self-treatment this mining population, raising fear development anti-malarial resistance. This prospective study, conducted 2015, aimed to estimate prevalence Plasmodium spp....
Abstract Purpose of Review Following Paraguay and Argentina, several countries from the Amazon region aim to eliminate malaria. To achieve this, all key affected vulnerable populations by malaria, including people working on gold mining sites, must be considered. What is situation malaria in these particular settings what are challenges? This literature review aims compile knowledge answer questions. Recent Findings The contexts which miners operate very heterogeneous: size localization...
Illegal gold miners in French Guiana, a overseas territory ('département') located Amazonia, often carry malaria parasites (up to 46.8%). While the Guiana Shield Region aims at elimination, high prevalence of Plasmodium this hard-to-reach population conjunction with frequent incorrect use artemisinin-based anti-malarials could favour emergence resistant parasites. Due geographical and regulatory issues usual control strategies cannot be implemented particular context. Therefore, new...
Illegal gold miners are currently key hosts for malaria in French Guiana (FG), with a risk of emergence resistance linked to improper use artemisinin-based combination therapy (ACT). The remoteness the mines and regulatory issues hinder their access health care. A quasi-experimental researched project (Malakit) implemented FG borders Brazil Suriname aimed at determining effectiveness distributed kits self-diagnosis self-treatment illegal miners, after training, strategic border staging...
An innovative and community-based intervention is implemented in the Guiana Shield to eliminate malaria among people involved artisanal small-scale gold mining. The consists of distribution self-management kits goldminers presumptive treatment for individuals at risk carrying
The Guiana Shield, a small region of South America, is currently one the main hotspots malaria transmission on continent. This Amazonian area characterised by remarkable socioeconomic, cultural, health, and political heterogeneity high degree regional cross-border population mobility, which has contributed to increase in past few years. In this context, cooperation control represents both challenge an indispensable initiative. Viewpoint advocates for creation cooperative mechanism...
A Dutch traveller returning from Suriname in early March 2017, presented with fever and severe acute liver injury. Yellow was diagnosed by (q)RT-PCR sequencing. During hospital stay, the patient's condition deteriorated she developed hepatic encephalopathy requiring transfer to intensive care. Although yellow has not been reported last four decades Suriname, vaccination is recommended World Health Organization for visitors this country.
The emerging resistance to artemisinin derivatives that has been reported in South-East Asia led us assess the efficacy of artemether-lumefantrine as first line therapy for uncomplicated Plasmodium falciparum infections Suriname. This drug assessment was performed according recommendations World Health Organization 2011. decreasing number malaria cases Suriname, which are currently limited migrating populations and gold miners, precludes any conclusions on artemether because adequate numbers...
Malaria is endemic in French Guiana (FG), South America. Despite the decrease cases local population, illegal gold miners are very affected by malaria (22.3% of them carried Plasmodium spp.). Self-medication seems to be common, but its modalities and associated factors have not been studied. The aim this study was evaluate parasite susceptibility drugs document behaviours that could contribute resistance selection miners.This multicentric cross-sectional conducted resting sites along...
Objectives Lead poisoning is a major public health problem worldwide. In French Guiana, overseas territory in South America, several studies have highlighted the massive lead impregnation of local population, but risk factors not yet been fully elucidated. People working informal gold mining share part their lifestyle with Guianese communities. The aim this was therefore to estimate level population and associated it. Methods This cross-sectional descriptive study based on data collected by...
"Phase I Clinical Trial of a Recombinant Malaria Vaccine Consisting the Circumsporozoite Repeat Region Plasmodium Falciparum Coupled to Hepatitis B Surface Antigen" published on Nov 1991 by The American Society Tropical Medicine and Hygiene.
Acute Zika virus infection usually presents with a self-limiting triad of fever, rash and arthritis. There is limited information on severe or lethal cases. We report three cases acute infection, confirmed polymerase chain reaction, in adult patients some co-morbidities. The showed rapid clinical deterioration hemorrhagic septic shock, exaggerated innate inflammatory responses pronounced coagulopathy, died soon after admission to the hospital. It remains unclear whether fatal outcomes were...
An interventional study named Malakit was implemented between April 2018 and March 2020 to address malaria in gold mining areas French Guiana, collaboration with Suriname Brazil. This innovative intervention relied on the distribution of kits for self-diagnosis self-treatment miners after training by health mediators, referred project as facilitators.
Most emerging pathogens are zoonoses and have a wildlife origin. Anthropization disruption of ecosystems favor the crossing inter-species barriers. We hypothesize that marginalized population undocumented goldminers in Amazon is at risk acquiring zoonoses.
Scaling-up an experimental intervention is always a challenge. On the border between French Guiana, Brazil and Suriname, interventional study demonstrated effectiveness of distributing self-diagnosis self-treatment kits (Malakits) to control malaria in mobile hard-to-reach populations. Its integration into Suriname's National Malaria Elimination Plan after 2-year experiment faced numerous challenges, including human resources cope with additional workload coordinators maintain motivation...
<title>Abstract</title> <bold>Background</bold>: In most countries engaged on the last mile towards malaria elimination, residual transmission mainly persists among vulnerable populations represented by isolated and mobile (often cross-border) communities. These are sometimes involved in informal or even illegal activities. regions with <italic>P. vivax</italic> specific biology of this parasite poses additional difficulties related to need for a radical treatment against hypnozoites prevent...