A5001655944- Mosquito-borne diseases and control
- Malaria Research and Control
- Parasitic Diseases Research and Treatment
- Parasite Biology and Host Interactions
- Freshwater macroinvertebrate diversity and ecology
- COVID-19 epidemiological studies
- Zoonotic diseases and public health
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Child Nutrition and Water Access
- Parasites and Host Interactions
- COVID-19 Clinical Research Studies
- Vaccine Coverage and Hesitancy
- Insects and Parasite Interactions
- Invertebrate Taxonomy and Ecology
- Vector-borne infectious diseases
- Public Health and Social Inequalities
- Trypanosoma species research and implications
- Fish Ecology and Management Studies
- Fish biology, ecology, and behavior
- Aquatic Invertebrate Ecology and Behavior
- Venezuelan Migration and Society
- Species Distribution and Climate Change
- Venomous Animal Envenomation and Studies
- Global Public Health Policies and Epidemiology
Central University of Venezuela
2016-2025
Hospital Clínico Universitario de Caracas
2023-2024
Academia Nacional de Medicina Venezuela
2021
University of Groningen
2019
University of Carabobo
2019
Bolivarian University of Venezuela
2013
University of Toronto
2009
United States Department of Agriculture
2007
Centers for Disease Control and Prevention
2007
International Institute of Tropical Forestry
2007
Venezuela's tumbling economy and authoritarian rule have precipitated an unprecedented humanitarian crisis. Hyperinflation rates now exceed 45,000%, health system is in free fall. The country experiencing a massive exodus of biomedical scientists qualified healthcare professionals. Reemergence arthropod-borne vaccine-preventable diseases has sparked serious epidemics that also affect neighboring countries. In this article, we discuss the ongoing measles diphtheria Venezuela their...
Differential distributions of Aedes aegypti and Ae. mediovittatus (potential inter-epidemic dengue vector) other mosquitoes colonizing bamboo pots in San Juan, Puerto Rico were studied along an urban-rural gradient. City regions (urban, suburban, rural) landscape elements within (forest [F], low-density housing [LDH], high-density [HDH]) identified using satellite imagery. species extensively overlapped LDH urban, rural areas. Mosquito showed their high specificity for (96.6% correct...
Abstract Dengue is a mosquito-borne viral disease of global impact. In Venezuela, dengue has emerged as one the most important public health problems urban areas with frequent epidemics since 2001. The long-term pattern this involved not only general upward trend in cases but also dramatic increase size and frequency epidemic outbreaks. By assuming that climate variability relevant influence on these changes time, we quantified periodicity incidence time-series data from two northern regions...
Malaria elimination in Latin America is becoming an elusive goal. cases reached a historical ~1 million 2017 and 2018, with Venezuela contributing 53% 51% of those cases, respectively. Historically, malaria incidence southern has accounted for most the country's total number cases. The efficient deployment disease prevention measures prediction spread to new regions requires in-depth understanding spatial heterogeneity on transmission dynamics. Herein, we characterized epidemiology from 2007...
The Guiana Shield, a small region of South America, is currently one the main hotspots malaria transmission on continent. This Amazonian area characterised by remarkable socioeconomic, cultural, health, and political heterogeneity high degree regional cross-border population mobility, which has contributed to increase in past few years. In this context, cooperation control represents both challenge an indispensable initiative. Viewpoint advocates for creation cooperative mechanism...
Dengue virus (DENV) transmission is spatially heterogeneous. Hence, to stratify dengue prevalence in space may be an efficacious strategy target surveillance and control efforts a cost-effective manner particularly Venezuela where hyperendemic public health resources are scarce. Here, we determine hot spots of seroprevalence the risk factors associated with these clusters using local spatial statistics regression modeling approach.From August 2010 January 2011, community-based...
As a continuation of series papers to improve the knowledge Ephemeroptera fauna Venezuelan Guayana's Uplands, an update families Leptophlebiidae, Euthyplociidae and Oligoneuriidae in region is presented. result, Paramaka incognita sp. nov. described, female Askola emmerichi described for first time, genera Askola, Hydrosmilodon Leentvaaria, subgenus Miroculis (Atroari) species (M.) marauiae are recorded time Venezuela.
Abstract Background Malaria incidence has reached staggering numbers in Venezuela. Commonly, Bolívar State accounted for approximately 70% of the country cases every year. Most cluster Sifontes municipality, a region characterized by an extractive economy, including gold mining. An increase migration to Sifontes, driven mining, fueled malaria spillover rest and region. Here samples collected 2018 were compared with previous study 2003/2004 describe changes parasites population structures...
Here we analyze patterns of human infection with Onchocerca volvulus (the cause river blindness) in different continents and ecologies. In contrast some geohelminths schistosome parasites whose worm burdens typically exhibit a humped pattern host age, O. vary markedly locality. To test the hypothesis that such differences are partly due to heterogeneity exposure vector bites, develop an age- sex-structured model for intensity infection, parasite regulation within humans vectors. The is...
Mosquito-borne pathogen transmission exhibits spatial-temporal variability caused by ecological interactions acting at different scales. We used local spatial statistics and geographically weighted regression (GWR) to determine the pattern of malaria incidence persistence in northeastern Venezuela. Seven 11 hot spots were detected using statistics, although disease was explained only for four those spots. The GWR models greatly improved predictions risk compared with ordinary least squares...
The World Health Organization (WHO) has set goals for onchocerciasis elimination in Latin America by 2015. Most of the six previously endemic countries are attaining this goal implementing twice a year (and some foci, quarterly) mass ivermectin (Mectizan®) distribution. Elimination transmission been verified Colombia, Ecuador and Mexico. Challenges remain Amazonian focus straddling Venezuela Brazil, where disease affects hard-to-reach Yanomami indigenous population. We provide evidence...
Environmental degradation facilitates the emergence of vector-borne diseases, such as malaria, through changes in ecological landscape that increase human-vector contacts and expand vector habitats. However, modifying effects environmental on climate-disease relationships have not been well explored. Here, we investigate rapid re-emergence malaria a transmission hotspot southern Venezuela explore synergistic degradation, specifically gold-mining activity, climate variation.In this...
Journal Article Factors Associated with Distribution of Anopheles aquasalis and oswaldoi (Diptera: Culicidae) in a Malarious Area, Northeastern Venezuela Get access Maria Eugenia Grillet 1 Vector Biology Laboratory, Instituto de Zoología Tropical. Facultad Ciencias, Universidad Central Venezuela, Apartado 47058, Caracas 1041-A, 1Current address: Département Sciences Biologiques, Faculté des Arts et Sciences, Université Montréal, C.P. 6128, succursale Centre-ville, Canada H3C 3J7. E-mail:...
ABSTRACT Malaria in South America remains a serious public health problem. Anopheles ( Nyssorhynchus ) darlingi is the most important malaria vector across tropical Latin America. Vector-targeted disease control efforts require thorough understanding of mosquito demographic and evolutionary patterns. We present analyze whole genomes 1094 A. (median depth 18x) from six American countries. observe deep geographic population structure, high genetic diversity including thirteen putative...
Since 2015, the Global Technical Strategy (GTS) for Malaria 2016-2030 has been adopted by World Health Organization (WHO) as a comprehensive framework to accelerate progress malaria elimination in endemic countries. This strategy sets target of reducing global incidence and mortality rates 90% 2030. Here it is sought evaluate Brazil's achievements towards reaching WHO GTS milestone Considering total number new cases main research question is: will Brazil reach goal 2030? Analytical...
Chagas Disease (CD), a chronic infection caused by the Trypanosoma cruzi parasite, is Neglected Tropical endemic to Latin America. With re-emergence in Venezuela during past two decades, spread of CD has proved susceptible to, and inhibitable digital, real-time surveillance system effectuated Citizen Scientists communities throughout country. The #TraeTuChipo (#BringYourKissingBug) campaign implemented January 2020, served as such strategy counting on community engagement define current...
Dengue viruses are a significant global health concern, causing millions of infections annually and putting approximately half the world's population at risk, as reported by World Health Organization (WHO). Understanding spatial temporal patterns dengue virus spread is crucial for effective prevention future outbreaks. By investigating these patterns, targeted surveillance control measures can be improved, aiding in management outbreaks dengue-affected regions. Curaçao, where endemic, has...
Abstract Background Onchocerciasis is caused by Onchocerca volvulus and transmitted Simulium species (black flies). In the Americas, infection has been previously described in 13 discrete regional foci distributed among six countries (Brazil, Colombia, Ecuador, Guatemala, Mexico Venezuela) where more than 370,000 people are currently considered at risk. Since 2001, disease control Venezuela relied on mass drug administration to at-risk communities. This report provides empirical evidence of...