A5103239137- Malaria Research and Control
- Mosquito-borne diseases and control
- Parasites and Host Interactions
- Transplantation: Methods and Outcomes
- Trypanosoma species research and implications
- Mechanical Circulatory Support Devices
- Pneumonia and Respiratory Infections
- Vector-borne infectious diseases
- Renal Transplantation Outcomes and Treatments
- Technology and Human Factors in Education and Health
- Travel-related health issues
- Vibrio bacteria research studies
- Respiratory viral infections research
- Hepatitis C virus research
- Toxoplasma gondii Research Studies
- Parasitic infections in humans and animals
- Research on Leishmaniasis Studies
- Hepatitis Viruses Studies and Epidemiology
- Immune Cell Function and Interaction
- Pneumocystis jirovecii pneumonia detection and treatment
- Impulse Buying and Technology Impacts
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and Mental Health
- Drug Transport and Resistance Mechanisms
- Artificial Intelligence in Healthcare and Education
Universidad de Extremadura
2025
Centro de Implantología Cirugía Oral y Maxilofacial
2025
United States Naval Medical Research Unit SOUTH
2012-2024
Universidad Científica del Sur
2023
Baylor Scott & White Health
2013-2022
Complejo Hospitalario de Cáceres
2021
Universidad Peruana Cayetano Heredia
2018
Peruvian University of Applied Sciences
2018
Central Texas Veterans Health Care System
2010
Texas A&M Health Science Center
2010
It is unclear whether extracorporeal CO
Abstract Purpose of Review Following Paraguay and Argentina, several countries from the Amazon region aim to eliminate malaria. To achieve this, all key affected vulnerable populations by malaria, including people working on gold mining sites, must be considered. What is situation malaria in these particular settings what are challenges? This literature review aims compile knowledge answer questions. Recent Findings The contexts which miners operate very heterogeneous: size localization...
During 2010-2012, an outbreak of 210 cases malaria occurred in Tumbes, the northern coast Peru, where no Plasmodium falciparum case had been reported since 2006. To identify source parasite causing this outbreak, we conducted a molecular epidemiology investigation. Microsatellite typing showed identical genotype all 54 available isolates. This was also to that parasites isolated 2010 Loreto region Peruvian Amazon and closely related clonet B, lineage previously during 1998-2000. These...
Abstract Interferon lambda 4 (IFNλ4) has shown antiviral activity against RNA viruses, including some coronaviruses. Besides, genetic variants of IFNL4 can be predictive the clearance viruses. However, little is known about effect these on SARS-CoV-2 infection. In this study, we investigated whether there was a relationship rs12979860 polymorphism with COVID-19. We found that T allele overexpressed in COVID-19 patients regard to general population without disease (36.16% vs. 26.40%, p = 6.4...
Understanding the mechanisms of drug resistance in Plasmodium vivax, parasite that causes most widespread form human malaria, is complicated by lack a suitable long-term cell culture system for this parasite. In contrast to P. falciparum, which can be more readily manipulated laboratory, insights about biology need inferred from studies. Here we analyze genomes parasites within 10 vivax infections Peruvian Amazon. Using next-generation sequencing show some analyzed region are likely...
Introduction: the recognition of emotions allows humans to adapt their social environment, allowing for communicative exchange, inclusion, and integral well-being people. Especially those older adults who are institutionalized. In fact, following containment measures since COVID-19, mandatory use masks in health centers nursing homes has been established, which implies a change ability understand react facial emotions. Objective: assess impact on emotional expressions institutionalized (old...
Abstract Malaria is a major health problem in Peru despite substantial progress achieved by the ongoing malaria elimination program. This study explored population genetics of 63 Plasmodium falciparum and 170 P. vivax cases collected Peruvian Amazon Basin between 2015 2019. Microscopy PCR were used for detection positive samples genotyped at neutral drug resistance-associated regions. The exhibited low nucleotide diversity (π = 0.02) whereas presented higher genetic 0.34). All (n 63) carried...
To compare all-cause and cause-specific mortality among 3 distinct groups: within-country, rural-to-urban migrants, rural urban dwellers in a longitudinal cohort Peru.
Abstract Peru was the first country where pfhrp2 and pfhrp3 gene deletions were detected despite fact that rapid diagnostics tests are not commonly used for confirmatory malaria diagnosis. This context provides a unique scenario to study dynamics of without apparent RDTs selection pressure. In this we characterized presence genes on 325 P. falciparum samples collected in Iquitos surrounding communities between 2011 2018 order understand deletion prevalence, potential associations with...
Plasmodium vivax transmission occurs throughout the tropics and is an emerging threat in areas of falciparum decline, causing relapse infections that complicate treatment control. Targeted sequencing for P. has been widely deployed to detect population structure geographic spread antimalarial diagnostic resistance. However, there are fewer such tools vivax. Leveraging global variation data, we designed four molecular inversion probe (MIP) genotyping panels targeting geographically...
Cutaneous leishmaniasis is endemic to South America where diagnosis most commonly conducted via microscopy. Patients with suspected were referred for enrollment by the Ministry of Health (MoH) in Lima, Iquitos, Puerto Maldonado, and several rural areas Peru. A 43-question survey requesting age, gender, occupation, characterization lesion(s), history leishmaniasis, insect-deterrent behaviors was administered. Polymerase chain reaction (PCR) on lesion materials at Naval Medical Research Unit...
As demonstrated with the novel coronavirus pandemic, rapid and accurate diagnosis is key to determine clinical characteristic of a disease improve vaccine development. Once infected person identified, hematological findings may be used predict outcome offer correct treatment. Rapid parameters are pivotal track infections during trials set protection status. This also applicable for re-emerging diseases like dengue fever, which causes outbreaks in Asia Latin America every 4 5 years. Some...
Malaria elimination efforts in Peru have dramatically reduced the incidence of cases Amazon Basin. To achieve elimination, detection asymptomatic and submicroscopic carriers becomes a priority. Therefore, should focus on tests sensitive enough to detect low-density parasitemia, deployable resource-limited areas affordable for large screening purposes. In this study, we assessed performance Malachite–Green LAMP (MG-LAMP) using heat-treated DNA extraction (Boil & Spin; B&S MG-LAMP) 283...
The ability to remember faces is essential for everyday life, with deficits indicative of some neurological conditions. Face recognition tasks vary considerably in their design (i.e., use the same or a different picture learning and recall inclusion exclusion nonface characteristics), which known impact performance levels. However, it unknown whether these features cause additional cognitive abilities be assessed. We preregistered three hypotheses, namely on face can best explained by:...
Two Plasmodium vivax recurrences in a Peruvian sailor with weight above the 60 kg (cap for primaquine dosage) highlight importance of adequate radical cure dosage patient treatment and control efforts, particularly within military.
ObjectivesAccuracy of malaria rapid diagnostic tests is threatened by Plasmodium falciparum with pfhrp2/3 deletions. This study compares gene deletion prevalence determined multiplex qPCR and conventional PCR (cPCR) using existing samples clonality previously microsatellite genotyping.MethodsMultiplex was used to estimate deletions in three sets collected patient from Eritrea Peru. The validated digital PCR. Sample classification compared cPCR, ROC analysis determine the optimal ΔCq...
transmission occurs throughout the tropics and is an emerging threat in areas of
Plasmodium falciparum infection threatens military populations deployed to highly malaria-endemic regions, such as Peruvian Army peacekeepers Central African Republic. During deployment, malaria cases were identified by microscopy and rapid diagnostic tests. After we performed diagnosis malachite green loop-mediated isothermal amplification photo-induced electron transfer PCR assays. We used ELISA test for P. C-terminal 19-kDa region merozoite surface protein 1-specific IgG from 97...