A5101983314- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Transplantation: Methods and Outcomes
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Heart Failure Treatment and Management
- Sepsis Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Organ Transplantation Techniques and Outcomes
- Vitamin D Research Studies
- Vitamin C and Antioxidants Research
- Disaster Response and Management
- Emergency and Acute Care Studies
- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Renal Transplantation Outcomes and Treatments
- Parathyroid Disorders and Treatments
- Acute Kidney Injury Research
- Disaster Management and Resilience
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Trauma and Emergency Care Studies
- Electrolyte and hormonal disorders
- Hip and Femur Fractures
- Blood transfusion and management
- Long-Term Effects of COVID-19
St Vincent's Hospital
2009-2025
St Vincent's Hospital Sydney
2016-2025
UNSW Sydney
2015-2025
The George Institute for Global Health
2015-2024
Saint Vincent's Catholic Medical Center
2009-2023
George Institute for Global Health
2012-2023
St. Vincent's Hospital
2009-2023
Arizona State University
2022
University at Albany, State University of New York
2022
Albany Medical Center Hospital
2022
Increased bone resorption predicts mortality and heightens during critical illness. Bisphosphonates are potent inhibitors of resorption. Whether bisphosphonate impacts clinical outcome intensive care unit (ICU) admission is unknown.We investigated the relationship between preadmission use in critically ill patients.This was a retrospective hospital-based analysis.The study conducted at tertiary referral hospital ICU.A total 7830 patients 2003 2014 participated study.The intervention included...
Patients with obesity are at increased risk for developing acute respiratory distress syndrome (ARDS). Some centers consider a relative contraindication to receiving extracorporeal membrane oxygenation (ECMO) support, despite growing implementation of ECMO ARDS in the general population.
Sedation practice in extracorporeal membrane oxygenation (ECMO) is challenging, and some studies suggest that pharmacokinetics of sedative drugs are altered by the circuitry components. We conducted an international survey sedation centers offering veno-venous ECMO for adult patients collaboration with Extracorporeal Life Support Organization. A total 102 respondents participated representing various experienced from around world. Fifty-eight percent responded on have a higher or much...
To determine the effect of two doses intramuscular cholecalciferol on serial serum 25-hydroxy-vitamin-D levels and pharmacodynamics endpoints: calcium, phosphate, parathyroid hormone, C-reactive protein, interleukin-6, cathelicidin in critically ill adults.Prospective randomized interventional study.Tertiary, academic adult ICU.Fifty adults with systemic inflammatory response syndrome.Patients were randomly allocated to receive a single dose either 150,000 IU (0.15 mU) or 300,000 (0.3...
Patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently develop arterial hyperoxaemia, which may be harmful. However, lower oxygen saturation targets also lead to harmful episodes of hypoxaemia. In this registry-embedded, multicentre trial, we randomly assigned adult patients VA-ECMO in an intensive care unit (ICU) either a conservative (target SaO2 92–96%) or liberal strategy 97–100%) through controlled administration via the ventilator and ECMO gas blender....
Background. Acute kidney injury (AKI) is a common complication postheart transplantation and associated with significant morbidity increased mortality. Methods. We conducted single-center, retrospective, observational cohort study of 109 consecutive patients undergoing heart between September 2019 2021 to determine major risk factors for, the incidence of, severe postoperative AKI as defined by Kidney Disease Improving Global Outcomes criteria in first 48-h posttransplantation impact that...
We present a 16-year-old male with severe acute respiratory and renal failure as result of Goodpasture syndrome, requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) for pulmonary haemorrhage. The patient received no systemic anticoagulation 25 26 ECMO days (20 consecutively) suffered coagulation-related adverse events. had subtherapeutic profile according to recommended guidelines during most this time. made full recovery without compromise, circuit failure, thrombotic events...
Abstract Background There is limited evidence regarding the effect of invasive mechanical ventilation practice post‐bilateral lung transplantation. Invasive may be associated with prolonged ventilation, particularly when referenced to donor anthropometrics. Methods This was a single‐centre retrospective cohort study that included consecutive adult bilateral transplant recipients between 2015 and 2021 who were ventilated for minimum 24 h post‐surgery. Lower higher tidal volume sub‐groups...
Rationale: Randomised clinical trials in intensive care often prioritize disease-focused outcomes rather than patient-centred outcomes. Objective: To report and evaluate the 'Daily Organ Support for patients on extracorporeal membrane oxygenation (ECMO)', DOSE outcome. This is a new longitudinal ordinal outcome receiving ECMO. Methods: Prospective, multicentre study 28 hospitals Australia New Zealand. Adult admitted to participating ICU between February 2019 September 2023 who underwent any...
BACKGROUND: Long-term outcomes and quality of life have been identified as core patient-centered for venoarterial extracorporeal membrane oxygenation (VA-ECMO) research. The aim this study is to investigate the incidence death or new disability at 12 months after initiation VA-ECMO. METHODS: Prospective, multicenter, registry-embedded cohort in 26 hospitals Australia New Zealand from February 2019 through April 2023. Adult patients admitted a participating ICU who underwent VA-ECMO were...