A5039858794- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Frailty in Older Adults
- Palliative Care and End-of-Life Issues
- Family and Patient Care in Intensive Care Units
- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tuberculosis Research and Epidemiology
- Nutrition and Health in Aging
- COVID-19 and Mental Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Organ Transplantation Techniques and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Emergency and Acute Care Studies
- Renal Transplantation Outcomes and Treatments
- Thermal Regulation in Medicine
- Heart Failure Treatment and Management
- Pneumonia and Respiratory Infections
- Neonatal Respiratory Health Research
- Pneumocystis jirovecii pneumonia detection and treatment
Columbia University
2016-2025
Columbia University Irving Medical Center
2013-2025
Immunogenics (United States)
2022
Pulmonary and Allergy Associates
2021
Texas Health Dallas
2021
New York Hospital Queens
2018-2020
NewYork–Presbyterian Hospital
2018-2020
Presbyterian Hospital
2020
Universidad Peruana Cayetano Heredia
2017-2019
Prisma
2017-2019
Over 40 000 patients with COVID-19 have been hospitalised in New York City (NY, USA) as of April 28, 2020. Data on the epidemiology, clinical course, and outcomes critically ill this setting are needed.
Hydroxychloroquine has been widely administered to patients with Covid-19 without robust evidence supporting its use. We examined the association between hydroxychloroquine use and intubation or death at a large medical center in New York City. Data were obtained regarding consecutive hospitalized Covid-19, excluding those who intubated, died, discharged within 24 hours after presentation emergency department (study baseline). The primary end point was composite of time-to-event analysis....
To characterize patients with coronavirus disease 2019 (covid-19) in a large New York City medical center and describe their clinical course across the emergency department, hospital wards, intensive care units.Retrospective manual record review.NewYork-Presbyterian/Columbia University Irving Medical Center, quaternary academic City.The first 1000 consecutive positive result on reverse transcriptase polymerase chain reaction assay for severe acute respiratory syndrome 2 (SARS-CoV-2) who...
Obesity is a risk factor for pneumonia and acute respiratory distress syndrome.
Rationale: Two distinct subphenotypes have been identified in acute respiratory distress syndrome (ARDS), but the presence of subgroups ARDS associated with coronavirus disease (COVID-19) is unknown. Objectives: To identify clinically relevant, novel COVID-19-related and compare them previously described subphenotypes. Methods: Eligible participants were adults COVID-19 at Columbia University Irving Medical Center. Latent class analysis was used to baseline clinical, respiratory, laboratory...
The risk factors for development of fibrotic-like radiographic abnormalities after severe COVID-19 are incompletely described and the extent to which CT findings correlate with symptoms physical function hospitalisation remains unclear. At 4 months hospitalisation, patterns were more common in those who underwent mechanical ventilation (72%) than did not (20%). We demonstrate that severity initial illness, duration ventilation, lactate dehydrogenase on admission leucocyte telomere length...
Abstract Background Nearly 30,000 patients with coronavirus disease-2019 (COVID-19) have been hospitalized in New York City as of April 14 th , 2020. Data on the epidemiology, clinical course, and outcomes critically ill COVID-19 this setting are needed. Methods We prospectively collected clinical, biomarker, treatment data adults laboratory-confirmed-COVID-19 admitted to two hospitals northern Manhattan between March 2 nd 1 st The primary outcome was in-hospital mortality. Secondary...
Vitamin A is important in regulating early lung development and alveolar formation. Maternal vitamin status may be an determinant of embryonic formation, deficiency a mother during pregnancy could have lasting adverse effects on the health her offspring. We tested this hypothesis by examining long-term supplementation with or beta carotene women before, during, after function their offspring, population chronic deficiency.
Contacts of tuberculosis index cases are at increased risk developing tuberculosis. Screening, preventive therapy, and surveillance for underused interventions in contacts, particularly adults. We developed a score to predict adult contacts cases.In 2002-06, we recruited aged 15 years or older with pulmonary who lived desert shanty towns Ventanilla, Peru. followed up until February, 2016. used Cox proportional hazards model identify case, contact, household factors from which derive classify...
Abstract Objective To characterize patients with coronavirus disease 2019 (COVID-19) in a large New York City (NYC) medical center and describe their clinical course across the emergency department (ED), inpatient wards, intensive care units (ICUs). Design Retrospective manual record review. Setting NewYork-Presbyterian/Columbia University Irving Medical Center (NYP/CUIMC), quaternary academic NYC. Participants The first 1000 consecutive laboratory-confirmed COVID-19. Methods We identified...
The psychological symptoms associated with having a family member admitted to the intensive care unit (ICU) during COVID-19 pandemic are not well defined.To examine prevalence of stress-related disorders, primarily posttraumatic stress disorder (PTSD), in members patients ICU approximately 90 days after admission.This prospective, multisite, mixed-methods observational cohort study assessed 330 (except New York City, which had random sample 25% all per month) between February 1 and July 31,...
Introduction: Cell-free DNA (CFDNA) is a reflection of both normal and tumor-derived released into the circulation through cellular necrosis apoptosis. We sought to determine whether tumor-specific plasma could be used as biomarker for tumor burden response therapy in an orthotopic ovarian cancer model. Methods: Female nude mice injected intraperitoneally with HeyA8 cells were treated either docetaxel alone or combination anti-angiogenic agents (AEE788 -- dual VEGFR EGFR antagonist EA5 –...
ABSTRACT Clinical manifestations of COVID-19 caused by the novel coronavirus SARS-CoV-2 are associated with age. While children largely spared from severe respiratory disease, they can present a SARS-CoV-2-associated multisystem inflammatory syndrome (MIS-C) similar to Kawasaki’s disease. Here, we show distinct antibody (Ab) responses in MIS-C compared adults causing acute distress (ARDS), and those who recovered mild There was reduced breadth specificity anti-SARS-CoV-2-specific antibodies...
BackgroundActive case-finding among contacts of patients with tuberculosis is a global health priority, but the effects active versus passive are poorly characterised. We assessed contribution to detection and compared sex disease characteristics between diagnosed through these strategies.MethodsIn shanty towns in Callao, Peru, we identified index followed up aged 15 years or older for tuberculosis. All were offered free programmatic entailing sputum smear microscopy clinical assessment....
Patients with obesity are at increased risk for developing acute respiratory distress syndrome (ARDS). Some centers consider a relative contraindication to receiving extracorporeal membrane oxygenation (ECMO) support, despite growing implementation of ECMO ARDS in the general population.
Lungs from older adult organ donors are often unused because of concerns for increased mortality. We examined associations between donor age and transplant outcomes among 8860 lung recipients using Organ Procurement Transplantation Network Lung Transplant Outcomes Group data. used stratified Cox proportional hazard models generalized linear mixed to examine both 1-year graft failure primary dysfunction (PGD). The rate was similar lungs 18–64 years, but severely ill (Lung Allocation Score...