Richard Totaro

ORCID: 0000-0002-1606-5197
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About
Contact & Profiles
Research Areas
  • Mechanical Circulatory Support Devices
  • Cardiac Arrest and Resuscitation
  • Respiratory Support and Mechanisms
  • Intensive Care Unit Cognitive Disorders
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Sepsis Diagnosis and Treatment
  • Atrial Fibrillation Management and Outcomes
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • SARS-CoV-2 and COVID-19 Research
  • Trauma Management and Diagnosis
  • Influenza Virus Research Studies
  • Cardiac Structural Anomalies and Repair
  • Acute Kidney Injury Research
  • Family and Patient Care in Intensive Care Units
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Health Systems, Economic Evaluations, Quality of Life
  • Simulation-Based Education in Healthcare
  • Travel-related health issues
  • Diabetes Management and Research
  • Academic Publishing and Open Access
  • Cardiac pacing and defibrillation studies
  • Meta-analysis and systematic reviews
  • Heart Failure Treatment and Management
  • Diabetes and associated disorders

The University of Sydney
2016-2025

Royal Prince Alfred Hospital
2004-2025

Prince Charles Hospital
2021

Society of Critical Care Medicine
2004

American College of Financial Services
2004

Intensive Care Society
2004

Royal North Shore Hospital
1997

The outcomes of survivors critical illness due to coronavirus disease (COVID-19) compared with non-COVID-19 are yet be established.

10.1164/rccm.202110-2335oc article EN cc-by-nc-nd American Journal of Respiratory and Critical Care Medicine 2022-03-08

Abstract Extracorporeal membrane oxygenation (ECMO) support has a high incidence of both bleeding and thrombotic complications. Despite clear differences in patient characteristics pathologies between veno-venous (VV) veno-arterial (VA) ECMO support, anticoagulation practices are often the same across modalities. Moreover, there is very little data on their respective coagulation profiles comparisons thrombin generation these patients. This study compares profile patients supported with...

10.1038/s41598-021-87026-z article EN cc-by Scientific Reports 2021-04-12

Objective To determine if lactic acidosis occurring after cardiopulmonary bypass could be attributed to the metabolic or other effects of epinephrine administration. Design Prospective, randomized study. Setting Postsurgical cardiothoracic intensive therapy unit. Patients Thirty-six adult patients, without acidosis, requiring vasoconstrictors for management hypotension bypass. Interventions Randomized administration either norepinephrine by infusion. Measurements and Main Results Hemodynamic...

10.1097/00003246-199710000-00019 article EN Critical Care Medicine 1997-10-01

Patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently develop arterial hyperoxaemia, which may be harmful. However, lower oxygen saturation targets also lead to harmful episodes of hypoxaemia. In this registry-embedded, multicentre trial, we randomly assigned adult patients VA-ECMO in an intensive care unit (ICU) either a conservative (target SaO2 92–96%) or liberal strategy 97–100%) through controlled administration via the ventilator and ECMO gas blender....

10.1007/s00134-024-07564-8 article EN cc-by-nc Intensive Care Medicine 2024-08-20

Superior vena cava drainage during venoarterial extracorporeal membrane oxygenation (ECMO) may reduce access insufficiency and differential is typically achieved via the femoral approach. Direct multistage jugular cannulation be optimal. Despite its use at select centers, this approach not well discussed in literature. We present five percutaneous jugulo-femoral ECMO initiations from our high-volume, intensivist-led service. Each case offers unique indication for direct SVC lieu of...

10.1097/mat.0000000000002466 article EN ASAIO Journal 2025-05-19

Use of extracorporeal membrane oxygenation (ECMO) for cardiorespiratory failure remains complicated by blood clot formation (thrombosis), triggered biomaterial surfaces and flow conditions. Thrombosis may result in ECMO circuit changes, cause red cell hemolysis, thromboembolic events. Medical device thrombosis is potentiated the interplay between properties, hemodynamic conditions patient pathology, however, contribution importance these factors are poorly understood because many vitro...

10.1002/advs.202401524 article EN cc-by Advanced Science 2024-05-17

Whilst myocarditis or myocardial injury due to severe acute respiratory syndrome coronavirus 2 infection is commonly reported, profound primary cardiac dysfunction requiring mechanical circulatory support, with the development of fulminant prior failure, rarely described. The endomyocardial biopsy (EMB) findings in these patients seldom are varied, and effective treatment unknown.

10.1093/ehjcr/ytac142 article EN cc-by-nc European Heart Journal - Case Reports 2022-04-01

10.1016/j.aucc.2022.05.002 article EN Australian Critical Care 2022-05-23

To describe the training and accreditation process behind an intensivist-led extracorporeal membrane oxygenation (ECMO) cannulation program, identify rate of complications associated with ECMO procedure.

10.1016/j.ccrj.2023.11.006 article EN cc-by-nc-nd Critical Care and Resuscitation 2023-12-14

Background: There is evidence that intensive glycaemic control decreases morbidity and mortality in surgical care unit patients. In traumatic brain injury, hyperglycaemia a prognostic indicator. Objective study design: This retrospective cohort describes the blood glucose level outcomes before after introduction of an insulin protocol to neurosurgical ICU. Methods: We analysed data on all patients admitted ICU during year before, after, July 2003 targeting patient (BGL) 4.4– 6.1mmol/L....

10.1016/s1441-2772(23)01020-7 article EN cc-by-nc-nd Critical Care and Resuscitation 2008-09-01

Crit Care Resusc ISSN: 1441-2772 1 June 2010 12 2 121-130 © C r i t a re Re sus c 20 10 www.jficm.anzca.edu.au/aaccm/journal/publications.htm Reviews hemisphere, including Australia and New Zeala The provision of intensive care in these countries other developed countries. experience help clinici ns elsewhere to tr illness associated with H1N1 2009. At the onset 2009 influenza p A virus undergoes periodic antigen shifts, resulting new strains. emergence strains provides necessary conditions...

10.1016/s1441-2772(23)01515-6 article EN cc-by-nc-nd Critical Care and Resuscitation 2010-06-01

Critically ill patients supported with venoarterial extracorporeal membrane oxygenation (VA ECMO) are at risk of developing severe arterial hyperoxia, which has been associated increased mortality. Lower saturation targets in this population may lead to deleterious episodes hypoxia. This manuscript describes the protocol and statistical analysis plan for Blend Limit OxygEN ECMO: A RanDomised ControllEd Registry (BLENDER) Trial.

10.1016/j.ccrj.2023.06.001 article EN cc-by-nc-nd Critical Care and Resuscitation 2023-08-04

Veno-venous extracorporeal membrane oxygenation is increasingly used for severe but potentially reversible acute respiratory failure in adults; however, there are limited data regarding long-term morbidity. At our institution, most patients requiring veno-venous have been followed up by a single physician. Our primary aim was to describe the serial morbidity respiratory, musculoskeletal and psychological functioning.A retrospective audit of inpatient outpatient medical records conducted. A...

10.1177/0310057x211042386 article EN Anaesthesia and Intensive Care 2021-11-01
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