- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Aortic Disease and Treatment Approaches
- Abdominal vascular conditions and treatments
- Vascular Procedures and Complications
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Renal and Vascular Pathologies
- Trauma and Emergency Care Studies
- Venous Thromboembolism Diagnosis and Management
- Patient Safety and Medication Errors
- Vascular anomalies and interventions
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Health and Disease Prevention
- Cardiac Ischemia and Reperfusion
- Health and Medical Research Impacts
- Cardiac Valve Diseases and Treatments
- Diversity and Career in Medicine
- Emergency and Acute Care Studies
- Cell Adhesion Molecules Research
- Innovations in Medical Education
- Healthcare Policy and Management
- Cardiac Arrest and Resuscitation
Sinai Health System
2010-2024
Cedars-Sinai Medical Center
2014-2023
American Association of Neurological Surgeons
2023
Committee on Publication Ethics
2021
The University of Texas Health Science Center at Houston
1980-2020
American Association for the Surgery of Trauma
2020
University of Maryland Medical System
2020
Harborview Medical Center
2020
University of Washington
2020
Cedars-Sinai Smidt Heart Institute
2020
Arterial fibrodysplasia affected 196 patients (172 females, 24 males) harboring a total of 316 diseased vessels. Renal artery lesions were documented in 152 adult and 25 pediatric patients. Superior mesenteric, celiac, common hepatic, external iliac arteries occasionally involved. Intimal fibroplasia medial hyperplasia are uncommon types arterial dysplasia. Medical represents continum disease, including pathologic processes heretofore categorized as subadventital or perimedial fibroplasia. A...
Seventy-two patients (39 females and 33 males), 9 to 84 years in age, exhibited a total of 94 renal artery macroaneurysms. Solitary aneurysms affected 53 patients, multiple occurred 19 patients. Arteriosclerotic changes, observed nearly 30% aneurysms, were considered secondary rather than primary processes most instances. Renal fibrodysplasia was an associated finding among 27 In 57 hypertensive evidence supportive contributing elevated blood pressure meager. Two experienced frank aneurysmal...
Prolonged hypoxia produces reversible changes in endothelial permeability, but the mechanisms involved are not fully known. Previous studies have implicated reactive oxygen species (ROS) and cytokines regulation of permeability. We tested whether prolonged alters permeability to increasing ROS generation, which amplifies cytokine production. Human umbilical vein cell (HUVEC) monolayers were exposed while secretion tumor necrosis factor-α (TNF-α), interleukin (IL)-1α, IL-6, IL-8 was measured....
Trauma patients are at high risk for developing venous thromboembolism (VTE). The VTE rate when enoxaparin sodium is dosed by anti-factor Xa (anti-Xa) trough level not well described.To determine whether targeting a prophylactic anti-Xa adjusting the dose would reduce in trauma patients.Single-institution, historic vs prospective cohort comparison study an urban, academic, I center. was enrolled from August 2014 to May 2015 and compared with admitted 2013 2014. who received adjusted...
Endothelial cells increase their secretion of the cytokine interleukin-6 (IL-6) during hypoxia, which then acts in an autocrine fashion to permeability cell monolayers. These responses are attenuated by antioxidants, suggesting that reactive oxygen species (ROS) participate signaling hypoxic endothelium. We tested whether mitochondria responsible for these ROS human umbilical vein endothelial exposed hypoxia. Oxidation probe 2′, 7′-dichlorodihydrofluorescein fluorescent dichlorofluorescein...
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Although recognition of chronic mesenteric ischemia has increased in recent years, this disorder continued to present diagnostic and therapeutic challenges.To examine the modern results surgical revascularization for ischemia.Retrospective review.University medical center.The management 24 consecutive patients (mean +/- SEM age, 58 3 years; 5 men, 19 women) who were undergoing treatment between 1986 1996 was reviewed.Surgical revascularization.Postoperative course, long-term graft patency...