- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Cancer Studies
- Prostate Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Venous Thromboembolism Diagnosis and Management
- Pelvic and Acetabular Injuries
- Cervical Cancer and HPV Research
- Cancer-related Molecular Pathways
- Hemostasis and retained surgical items
- Cancer-related molecular mechanisms research
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
Riga East University Hospital
2021-2024
Riga Stradiņš University
2023
The role of HPV in the survival prognosis patients with head and neck squamous cell carcinoma, especially laryngeal carcinoma (LSCC) hypopharyngeal (HPSCC), is still somewhat ambiguous. present study aimed to explore significance tumor suppressor proteins HPV16 E6 E7 oncoproteins assessment oropharyngeal (OPSCC), LSCC, HPSCC associated high-risk (HR-) low-risk (LR-) infections. By utilizing molecular immunohistochemical investigations HNSCC samples patient data, univariate multivariate...
Human papillomavirus (HPV) was proven to play a significant role in cancer development the oropharynx. However, its of laryngeal (LSCC) and hypopharyngeal squamous cell carcinoma (HPSCC) remains be clarified. High-risk HPV (HR-HPV) viral proteins E6 E7 are considered pertinent HPV-related carcinogenesis. Hence, our aim estimate LSCC HPSCC for HR-HPV DNA, p16, E6/E7 oncoprotein status by using molecular virology immunohistochemistry methods. The prevalence HPV16 infection 22/41 (53.7%) 20/31...
Microvascular flap surgery is a widely acknowledged procedure for significant defect reconstruction. Multiple complication risk factors have been identified, yet there are limited data on laboratory biomarkers the prediction of loss. The controlling nutritional status (CONUT) score has demonstrated good postoperative outcome assessment ability in diverse surgical populations. We aim to assess predictive value CONUT complications microvascular surgery. This prospective cohort study includes...
: Microvascular flap surgery has become a routine option for defect correction. The role of von Willebrand factor antigen (VWF:Ag) in the pathophysiology complications is not fully understood. We aim to investigate predictive value VWF:Ag microvascular and explore relationship between chronic inflammation VWF:Ag.