A5088596510- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- 3D Printing in Biomedical Research
- Neonatal Respiratory Health Research
- COVID-19 Impact on Reproduction
- Electrospun Nanofibers in Biomedical Applications
- Plasma Applications and Diagnostics
- Curcumin's Biomedical Applications
- Osteoarthritis Treatment and Mechanisms
- Organ Transplantation Techniques and Outcomes
- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- Burn Injury Management and Outcomes
- Hydrogen's biological and therapeutic effects
- Bone Tissue Engineering Materials
- Nanoplatforms for cancer theranostics
- Antimicrobial Peptides and Activities
- Lipid Membrane Structure and Behavior
- Liver physiology and pathology
- Polydiacetylene-based materials and applications
- Metal-Organic Frameworks: Synthesis and Applications
- Silk-based biomaterials and applications
- Cancer Cells and Metastasis
Shahid Beheshti University of Medical Sciences
2021-2025
San Francisco VA Medical Center
2023
University of California, San Francisco
2023
Royan Institute
2023
Academic Center for Education, Culture and Research
2023
Abstract Background Intra-articular injection of mesenchymal stromal cells (MSCs) with immunomodulatory features and their paracrine secretion regenerative factors proposed a noninvasive therapeutic modality for cartilage regeneration in knee osteoarthritis (KOA). Methods Total number 40 patients KOA enrolled two groups. Twenty received intra-articular 100 × 10 6 allogeneic adipose-derived (AD-MSCs), 20 as control group placebo (normal saline). Questionnaire-based measurements, certain serum...
Despite many efforts, breast cancer remains one of the deadliest cancers and its treatment faces challenges related to drug side effects metastasis. Combining 3D printing nanocarriers has created new opportunities in treatment. In this work, 3D-printed gelatin-alginate nanocomposites containing doxorubicin-loaded niosomes (Nio-DOX@GT-AL) were recruited as an advanced potential pH-sensitive delivery system. Morphology, degradation, release, flow cytometry, cell cytotoxicity, migration,...
Combination therapy has been considered one of the most promising approaches for improving therapeutic effects anticancer drugs. This is first study that uses two different antioxidants in full-characterized niosomal formulation and thoroughly evaluates their synergistic on breast cancer cells. In this study, in-silico studies hydrophilic hydrophobic drugs (ascorbic acid: Asc curcumin: Cur) interactions release were investigated validated by a set vitro experiments to reveal significant...
There is an unmet need to develop potent therapeutics against cancer with minimal side effects and systemic toxicity. Thymol (TH) herbal medicine anti-cancer properties that has been investigated scientifically. This study shows TH induces apoptosis in cancerous cell lines such as MCF-7, AGS, HepG2. Furthermore, this reveals can be encapsulated a Polyvinyl alcohol (PVA)-coated niosome (Nio-TH/PVA) enhance its stability enable controlled release model drug the region.TH-loaded (Nio-TH) was...
Inflammatory and autoimmune diseases are among the most challenging disorders for health care professionals that require systemic immune suppression which associates with various side effects. Mesenchymal stromal cells (MSCs) capable of regulating responses, mainly through paracrine effects cell-cell contact. Since MSCs advanced therapy medicinal products (ATMPs), they must follow Good Manufacturing Practice (GMP) regulations to ensure their safety efficacy. In this study, we evaluated...