A5011110486- Advancements in Transdermal Drug Delivery
- Immune Cell Function and Interaction
- RNA Interference and Gene Delivery
- Immunotherapy and Immune Responses
- Biochemical Analysis and Sensing Techniques
- Regulation of Appetite and Obesity
- Advanced Glycation End Products research
- Tissue Engineering and Regenerative Medicine
- Biochemical effects in animals
- Cardiac Ischemia and Reperfusion
- Diet, Metabolism, and Disease
- Essential Oils and Antimicrobial Activity
- CAR-T cell therapy research
- Nanoplatforms for cancer theranostics
- Monoclonal and Polyclonal Antibodies Research
- Helicobacter pylori-related gastroenterology studies
- Cancer, Hypoxia, and Metabolism
- Bacteriophages and microbial interactions
- Nutritional Studies and Diet
- Advanced biosensing and bioanalysis techniques
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Cancer, Lipids, and Metabolism
- Bacterial biofilms and quorum sensing
- T-cell and B-cell Immunology
Islamic Azad University Medical Branch of Tehran
2017-2024
Zanjan University of Medical Sciences
2017-2024
Tehran University of Medical Sciences
2016-2023
University of Zanjan
2022
Tabriz University of Medical Sciences
2015-2016
Iran University of Medical Sciences
2016
Novindiet Clinic
2015
Harvard University
2015
Shiraz University of Medical Sciences
2009-2013
The aim of this study was to assess whether baseline echocardiographic measures left ventricular (LV) size and function predict the development symptomatic heart failure or cardiac death (major adverse events, MACE) in patients treated with anthracyclines who have a pre-chemotherapy ejection fraction (LVEF) between 50 59%.Patients an LVEF 59% before were selected. In these patients, LV volumes, LVEF, peak longitudinal strain (GLS) measured. Individuals followed for MACE all-cause mortality...
Combination therapy has been considered one of the most promising approaches for improving therapeutic effects anticancer drugs. This is first study that uses two different antioxidants in full-characterized niosomal formulation and thoroughly evaluates their synergistic on breast cancer cells. In this study, in-silico studies hydrophilic hydrophobic drugs (ascorbic acid: Asc curcumin: Cur) interactions release were investigated validated by a set vitro experiments to reveal significant...
This in vitro study evaluated the shear bond strength (SBS) between ceramic brackets (CBs) and resin composite restorations (RCRs) prepared using different surface treatments. The findings were also compared with a similar that used stainless steel (SSBs). Forty-five premolars restored nano-hybrid (Tetric EvoCeram) randomly assigned to three treatment groups: group 1, 5 per cent hydrofluoric acid (HF); 2, air abrasion (50 μm alumina particles); 3, diamond bur. Specimens bonded CBs...
Dendritic cells are important in initiating immune responses; therefore, a range of dendritic cell–based approaches have been established to induce response against cancer cells. However, the presence immunosuppressive mediators such as adenosine tumor microenvironment reduces efficacy immunotherapy. In this study, we investigated whether blockade A2A receptor with selective antagonist and CD73 inhibitor may increase vaccine. According findings, therapeutic combination reduced growth,...
Abstract A number of molecular biofactors have been documented in pathogenesis and poor prognosis colorectal cancer (CRC). Among them, the Hypoxia-Inducible Factor (HIF-1a) is frequently reported to become over-expressed, its targeting could restrict control a variety essential hallmarks CRC. Niosomes are innovative drug delivery vehicles with encapsulating capacity for co-loading both hydrophilic hydrophobic drugs at same time. Also, they can enhance local accumulation while minimizing dose...
Introduction: Designing and developing drug delivery systems has received tremendous attention during the last decade. The treatment of cancer cells is a complicated process due to existence different biological pathways. Therefore, co-delivery drugs could have synergic effect on process.Materials Methods: In this study, types span (20, 60, 80) cholesterol were utilized formulate tamoxifen/curcumin co-loaded niosomes as carrier system for breast chemotherapy. Niosome characterization was...
Introduction: The critical role of regulatory T (Treg) cells in dampening immune responses against tumor is apparent. Therefore, several methods have been introduced for eliminating Treg. Among them, inducing Treg expressing Foxp3 transcription factor a hopeful approach to decrease the frequency Tregs. In current study, we used chimeric FoxP3-Fc(IgG) fusion construct/protein effectively stimulate cells. Materials and Methods: Previously constructed DNA vaccine its protein counterpart were...
Background: The prevalence rate of type 2 diabetes (T2DM) is increasing worldwide, and the role diet in its etiology has been established. Dietary inflammatory index (DII) attracted significant attention evaluating associations between diseases due to chronic inflammation as an underlying cause numerous disease processes. Therefore, relationship DII score risk T2DM evaluated Iranian population for first time. Methods: 113 newly diagnosed patients 226 apparently disease-free control cases...
Oral squamous cell carcinoma (OSCC) is the most common cancers arising from head and neck region. There growing evidence that lncRNAs play an important role in OSCC progression. The study aims to investigate correlations between expression levels of LncRNAs PARROT, MYCNUT, DANCR, KTN1-AS1 with clinicopathological characteristics finding suitable biomarkers for OSCC.Total related HNSC trascriptomics data were downloaded lncRNADisease v2.0 database xenabrowser, respectively. Then, ACO was...