- Periodontal Regeneration and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Dental Implant Techniques and Outcomes
- Bone and Dental Protein Studies
- Bone Tissue Engineering Materials
- Bone Metabolism and Diseases
- Fluoride Effects and Removal
- Anatomy and Medical Technology
- Microbial Metabolism and Applications
- Sesquiterpenes and Asteraceae Studies
- Oral and Maxillofacial Pathology
- dental development and anomalies
- Natural Compounds in Disease Treatment
- Cholinesterase and Neurodegenerative Diseases
- Cancer Research and Treatments
- Head and Neck Surgical Oncology
- Monoclonal and Polyclonal Antibodies Research
- Alkaloids: synthesis and pharmacology
- Tissue Engineering and Regenerative Medicine
- Dental Radiography and Imaging
- Cancer-related molecular mechanisms research
- Reconstructive Facial Surgery Techniques
- Chemical synthesis and alkaloids
- Plant biochemistry and biosynthesis
- Plant Gene Expression Analysis
Xi'an Jiaotong University
2015-2024
Chongqing Medical University
2021
ORCID
2021
Hubei University of Science and Technology
2018
Stomatology Hospital
2015
Maxillary defects are usually rehabilitated by a prosthetic obturator. This study aimed to evaluate the functioning of obturators prosthesis in patients with unilateral after maxillectomy. Of 49 patients, 28 underwent maxillectomy as result tumor ablative surgery, and acquired maxillary defects. Evaluation function was performed applying Obturator Functional Scale (OFS). From total were treated follows: 9 conventional retained obturator (COP), 11 (39%) an enhanced retentive stud attachment...
Lycorine has been revealed to inhibit the development of many kinds malignant tumors, including glioblastoma multiforme (GBM). Although compelling evidences demonstrated Lycorine's inhibition on cancers through some peripheral mechanism, in-depth mechanism studies Lycotine's anti-GBM effects still call for further exploration. Epidermal Growth Factor Receptor (EGFR) gene amplification and mutations are most common oncogenic events in GBM. Targeting EGFR by small molecular inhibitors is a...
Objective There is a need for cancer imaging in the clinic and operating room. We have shown that fluorescently labeled antibodies can detect microscopic islands of head neck cells using modified intraoperative microscopes preclinical animal studies. Here we evaluated optimal targeting molecule clinical translation. Method assessed vitro binding EGFR (cetuximab/Erbitux panitumumab/Vectibix) an antibody mimetic (anti‐EGFR affibody) multiple cell lines (SCC5, OSC19, FADU). To compare vivo...
Aim : To assess the effects of bone morphogenetic protein (BMP)-2, BMP-4, and BMP-7 on human periodontal ligament stem cells (PDLSC) proliferation osteogenic differentiation. Methods PDLSCs were isolated by an immunomagnetic method. Cell surface antigen (CD146, CD44, CD34) expression pluripotency (osteogenic adipogenic) determined. In doseresponse time-course experiments, cultured treated with individual BMPs, a combination BMPs in 1:1 ratios, mixture all three (1:1:1 ratio). dose-response...
Abstract Aim To investigate the effects of bone morphogenetic proteins (BMPs) 2, 4, and 7 on proliferation osteogenic differentiation in human periodontal ligament stem cells (PDLSCs). Methods PDLSCs were isolated by an immunomagnetic method. Expression cell surface antigens CD146, CD44, CD34, pluripotency (osteogenic adipogenic) measured. Cultured treated, dose- time-dependent experiments, with single BMPs, 1:1 combinations, a mix all three BMPs (1:3 each). For dose-dependent incubated for...
Abstract Background/Aim: Long noncoding RNA TARID (lncRNA ) can activate the tumor suppressor TCF21 in tumorigenesis by inducing promoter demethylation. However, impact on lncRNA and its variants of coronary artery disease (CAD) are poorly understood. Methods We performed a case-control study enrolling 949 case patients 892 controls to assess genotype. Five were genotyped TaqMan assay. 20 used evaluate expression TARID. The qRT-PCR cell cycle analysis applied examined proliferation...